Salient structural elements based texture synthesis

Salient structural elements are ubiquitous in natural textures, and their distribution exhibits some stochastic distribution features. Current texture synthesis algorithms can neither preserve the integrity of the elements nor capture this distributive information. We present an algorithm to treat this high-level visual information. Here, we address the issue by taking specific care of the structural elements. Our texture synthesis process grows the target texture one structural element at a time. A Markov ...     

Racing to the precipice: a model of artificial intelligence development

This paper presents a simple model of an AI (artificial intelligence) arms race, where several development teams race to build the first AI. Under the assumption that the first AI will be very powerful and transformative, each team is incentivised to finish first—by skimping on safety precautions if need be. This paper presents the Nash equilibrium of this process, where each team takes the correct amount of safety precautions in the arms race. Having extra development teams and extra enmity between teams can increase the danger of an AI disaster, especially if risk-taking is more important than skill in developing the AI. Surprisingly, information also increases the risks: the more teams know about each others’ capabilities (and about their own), the more the danger increases. Should these results persist in more realistic models and analysis, it points the way to methods of increasing the chance of the safe development of AI.     

ADL: An Activity Description Language for Real-Time Networks

This paper introduces and motivates ADL, a new formal notation for the specification of the temporal and functional behaviour of concurrent processes. ADL is tailored to be directly compatible with the DORIS design method. It combines a graphical Activity State-Machine (ASM) notation and a model-based Activity Functional Behaviour (AFB) notation. The abstract syntax, and static and dynamic semantics for the ASM notation are given, the dynamic semantics being given proof-theoretically in many-sorted logic extended with the RTL ‘occurrence’ relation, Θ, and the ERTL ‘holding’ relation, Φ. ADL is used to specify a small network, and proofs are given of its timeliness and safety properties. Received November 1998 / Accepted in revised form May 2000     

Spinal neurilemmomas and neurofibromas: central dot sign in postgadolinium MRI

The MR studies of three histologically proven spinal neurilemmomas and neurofibromas were reviewed retrospectively. There were two benign neurilemmomas (schwannomas) and one neurofibroma. The common characteristic of these cases was a central low intensity focus ("dot") seen on postcontrast T1-weighted imaging. The low intensity foci corresponded histologically to a congeries of changes including edema, microcysts, foam cells, hyalinization of blood vessels, old hemorrhage, and dystrophic calcification.     

Laparoscopic vs. open wedge biopsy of the liver

The number of people smoking free-base cocaine, or "crack," has increased dramatically in recent years. Concomitantly, the literature describing complications of such use has grown as well. Adverse pulmonary effects are being increasingly noted, such as respiratory symptoms, pulmonary hemorrhage, pulmonary edema, asthma, and pulmonary barotrauma. These and other pulmonary effects are reviewed.     

Commentary on "Publishing opinions: A note on the usefulness of commentaries."

Comments on J. J. Christensen-Szalanski and L. R. Beach's (see record 1984-21471-001) conclusion that the attention given to commentaries and replies to articles did not justify the extra space. The author indicates that a 40% increase in space was associated with a 91% increase in citations; data do not argue against the use of commentaries. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

New Beta-lactamases in Candidate Phyla Radiation: Owning Pleiotropic Enzymes Is a Smart Paradigm for Microorganisms with a Reduced Genome

The increased exploitation of microbial sequencing methods has shed light on the high diversity of new microorganisms named Candidate Phyla Radiation (CPR). CPR are mainly detected via 16S rRNA/metabarcoding analyses or metagenomics and are found to be abundant in all environments and present in different human microbiomes. These microbes, characterized by their symbiotic/epiparasitic lifestyle with bacteria, are directly exposed to competition with other microorganisms sharing the same ecological niche. Recently, a rich repertoire of enzymes with antibiotic resistance activity has been found in CPR genomes by using an in silico adapted screening strategy. This reservoir has shown a high prevalence of putative beta-lactamase-encoding genes. We expressed and purified five putative beta-lactamase sequences having the essential domains and functional motifs from class A and class B beta-lactamase. Their enzymatic activities were tested against various beta-lactam substrates using liquid chromatography-mass spectrometry (LC-MS) and showed some beta-lactamase activity even in the presence of a beta-lactamase inhibitor. In addition, ribonuclease activity was demonstrated against RNA that was not inhibited by sulbactam and EDTA. None of these proteins could degrade single- and double-stranded-DNA. This study is the first to express and test putative CPR beta-lactamase protein sequences in vitro. Our findings highlight that the reduced genomes of CPR members harbor sequences encoding for beta-lactamases known to be multifunction hydrolase enzymes.     

Scene-based nonuniformity correction with video sequences and registration

We describe a new, to our knowledge, scene-based nonuniformity correction algorithm for array detectors. The algorithm relies on the ability to register a sequence of observed frames in the presence of the fixed-pattern noise caused by pixel-to-pixel nonuniformity. In low-to-moderate levels of nonuniformity, sufficiently accurate registration may be possible with standard scene-based registration techniques. If the registration is accurate, and motion exists between the frames, then groups of independent detectors can be identified that observe the same irradiance (or true scene value). These detector outputs are averaged to generate estimates of the true scene values. With these scene estimates, and the corresponding observed values through a given detector, a curve-fitting procedure is used to estimate the individual detector response parameters. These can then be used to correct for detector nonuniformity. The strength of the algorithm lies in its simplicity and low computational complexity. Experimental results, to illustrate the performance of the algorithm, include the use of visible-range imagery with simulated nonuniformity and infrared imagery with real nonuniformity.