Evidence for a dual-factor concept of psychopathological emotional deficit: anhedonia and sensation-seeking

Correlations between measures of anhedonia and sensation-seeking were calculated in two psychiatric samples. The correlations indicated that, despite their conceptual similarity, the two represent different motivational deficits. Ther correlates appeared to indicate that sensation-seeking represents neurotic inhibition, while anhedonia reflects a separate motivational deficit apparently characteristic of process schizophrenics.     

Rotating disc studies of the vitreous carbon—sodium polysulphide interphase

Steady-state current-potential measurements have been made at the vitreous carbon-sodium polysulphide (liquid) interphase at temperatures of 305 and 350°C. Molten Na₂S₃ and Na₂S₅ were employed; the results obtained were not very dependent on melt composition.Evidence was found for at least three electrode processes: (a) near the equilibrium potential a diffusion-controlled redox reaction occurs; (b) at cathodic potentials a diffusion-limited reaction proceeds at an electrode covered by a sodium polysulphide film; and (c) at anodic potentials globules of sulphur are produced on the electrode surface.     

The effect of electrode orientation upon the anodic behaviour of the carbon-sodium polysulphide interphase at 350°C :- A study using thin layer cell techniques

The results obtained from thin layer cell studies verify the conclusions drawn from earlier work^3–5. Passivation occurs more readily for an electrode positioned vertically downwards. The sulphur, formed as spheroidal globules in the liquid state, does not wet the electrode surface. For an electrode positioned vertically upwards, globules are able to rise from the anode as a direct consequence of the density difference between sulphur and the polysulphide melt. They subsequently move to the cathode with velocities depending on their size.     

Clostridium perfringens infection complicating chemotherapy for choriocarcinoma

A case of Clostridium perfringens sepsis and gas gangrene complicating chemotherapy for gestational choriocarcinoma is reported. The infection was eradicated using antibiotics, surgery, and hyperbaric oxygen therapy. The pathophysiology, diagnosis, and treatment of this unusual but often lethal complication are reviewed.     

Prevention of phagosome-lysosome fusion in cultured macrophages by sulfatides of Mycobacterium tuberculosis

Intracellular parasites (e.g., Mycobacterium tuberculosis, Toxoplasma gondii, and some Chlamydiae) may promote their survival within the host by acting from within phagosomes to prevent phagolysosome formation, thus avoiding exposure to the lysosomal hydrolases. The present studies demonstrate that when sulfatides of M. tuberculosis (anionic trehalose glycolipids largely responsible for the neutral red reactivity of virulent strains) are administered to cultured mouse peritoneal macrophages, they accumulate in the secondary lysosomes, which are rendered incompetent for fusion with phagosomes containing suitable target particles such as viable yeasts. This antifusion effect is also exhibited when small amounts of sulfatide are introduced directly into phagosomes by attachment to the target yeasts prior to their ingestion. The sulfatides evidently exert a selective inhibitory influence on membrane fusion, analogous to what occurs typically when macrophage cultures are infected with tubercle bacilli. This effect may be due to ionic interaction between the polyanionic micelles of bacterial sulfatide and organelle membranes, modifying the latter and inducing dysfunction.     

Symbol synchronization using baud-rate sampling anddata-sequence-dependent signal processing

An algorithm for symbol timing recovery using baud-rate sampling is presented. Using this algorithm, the decoded data sequence is scanned for particular data patterns that yield samples which need only to be added or subtracted to give an estimate of the required timing function. The statistics of occurrence of these data patterns are calculated for random binary data. The variance of the timing function estimates is calculated for pulses with raised-cosine spectra that have been degraded by quadratic delay distortion and is shown to be lower, in most cases, than for other synchronizers using baud-rate sampling