负载氯喹的骨靶向纳米颗粒打破肿瘤细胞增殖与骨吸收之间的恶性循环

肿瘤细胞增殖与骨吸收之间的恶性循环加剧了骨肿瘤的进展和转移风险.为此,我们设计并制备了聚乙二醇-阿仑膦酸钠修饰的聚多巴胺(PPA)纳米粒子,并在其表面负载自噬抑制剂氯喹(CQ),期望利用该治疗载体(PPA/CQ)打破肿瘤细胞增殖与骨吸收之间的恶性循环,从而有效地治疗骨肿瘤.实验证明,PPA/CQ可以有效地富集到骨组织,...     

The characteristics of waves around an entrance of a lagoon in South China Sea

The characteristics of the waves around a lagoon entrance in South China Sea were observed during the past one and half years based on the wave measurements.The...     

洁具高压注浆成形坯料粘土成分研究的新进展

本文介绍了国外关于洁具高压注浆成形坯料粘土成分研究的新进展．为国内同行提供一定的参考作用。     

基于DSP的嵌入式系统的程序引导设计

作对以DSP为核心的嵌入式系统的程序引导功能进行了深入的研究及分析,并以TI公司的TMS320C33芯片为实例,归纳了其实现流程及设计方案,从硬件和软件两个方面阐述了实现该功能的关键点和值得注意的地方。该设计已被应用于一个配电网环网柜智能终端装置。运行实践表明,是一种简便、可靠的方案。     

可与氟树脂基板相匹敌的热可塑性树脂基板材料

概述了可以与氟树脂基板相匹敌的低介质特性的热可塑性树脂基板材料的开发和应用。     

回收草铵磷生产过程废溶剂的工艺设计及优化

针对草铵磷生产过程产生的废溶剂,设计了3种工艺流程用以回收其中的四氢呋喃、甲基亚磷酸二乙酯、亚磷酸三乙酯、混合三甲苯等有用组分. 分别对3种工艺路线进行实验计算,以产品的纯度、收率、能耗及设备造价为指标,考察分析确定最佳的工艺方案,为废溶剂的资源化再生利用提供可行方案.     

双极线性稳压器中子辐射位移效应研究

双极线性稳压器广泛应用于空间设备,中子辐射效应不容忽视。对国产双极线性稳压器在不同负载偏置下的中子辐射效应开展研究。试验过程中发现,负载越大,位移损伤效应越明显。试验后通过加载不同负载的详细在线测试发现,不同偏置下的输出电压差异是由于负载的不同引起的。辐照偏置对双极线性稳压器的位移损伤无显著影响,但中子位移效应导致了双极线性稳压器的带载能力严重降低,使其失去负载调整能力。因此,在工程评估时,应结合应用需求,选择合理的负载进行评估。     

RCS－Ⅰ反应堆堆芯模拟程序

本文介绍堆芯三维物理—热工水力耦台计算程序ＲＣＳ－Ｉ（ＲｅａｃｔｏｒＣｏｒｅＳｉｍｕｌａｔｏｒ）．其中子学模型采用先进的粗网格节块格林函数法，热工水力计算模型采用于通道分析方法．通过考虑多种反馈，该程序比较真实地描述堆芯的燃耗过程，具有临界、燃耗、中毒、跟踪和倒料等多种功能，可用于动力堆和研究堆的设计．     

40万吨／年加氢精制装置进料泵改造

为了满足加氢精制进料泵工作负荷增加５０％的需要,对该泵进行了技术改造,投入运转后各项指标均达到要求,经济效益显著。     

Formation of stable crystalline connecting bridges during the fabrication of polypropylene microporous membrane

The influence of hot stretching ratio and stretching temperature on the connecting bridge structure formed during the fabrication of polypropylene microporous membrane was studied. It was found that with the increase of stretching ratio to 200 % under temperature of 130 °C, bridge length was increased. Under the stretching ratio of 100 %, the main melting peak became wider, whereas similar phenomenon could not be seen under temperature of 110 °C. Under the ratio of 200 % and temperature of 130 °C, strong bridge structure lead to appearance of small shoulder on the right of main melting peak. Compared with that only through cold stretching, more connecting bridges were initiated during hot stretching. The unrestrained tie chains due to the chain disentanglement under high temperature, which were not involved in the annealing crystallization and cold stretching, could be stretched and crystallized into bridges. At the same time, some chains could also be pulled out from the initial lamellae. All these contributed to the increase of bridge number. During hot stretching, the broken bridges merged with other stable bridges and some bridges adhere to each other, resulting in the formation of stable bridges, which will be helpful to the stabilization of pore structure.