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121.
Current concepts to achieve product commonality follow static approaches. To achieve economies of scale, standards are defined across the product program. However, these standards typically need to be compromised at new product introductions due to unforeseen innovations and economies of scale decrease over time. Accordingly platform standards need to be re-defined.This paper presents an approach for adaptive product platforms. Degrees of freedom in product and process design are managed pro-actively based on functional and technological models. This way adaptivity towards product innovation can be ensured. The concept of adaptive modular platforms is explained based on a practical application. 相似文献
122.
Hans Schweighardt Maximilian Schuh Abdelhamid Mohamed Abdelhamid Josef Böhm und Josef Leibetseder 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1980,170(5):355-359
Zusammenfassung Eine schnelle, spezifische HPLC-Methode zum quantitativen Nachweis von Ochratoxin A sowohl in Lebens- und Futtermitteln als auch im Mischfutter wird vorgestellt.Ochratoxin A wird nach Vorreinigung im Schütteltrichter durch die mobile Phase Methanol/dest. Wasser (70+30)+1%. Essigsäure 100% von der Spherisorb S5 ODS-HPLC-Trennsäule eluiert und im Fluorescenzdetektor nachgewiesen.Im Bereich von 50 und 500 ppb weisen die mittleren Auffindungsraten rund 50%, bei nur geringer Schwankungsbreite (Variationskoeffizient 10,24% und 23,650 auf. 5 ppb können eindeutig erfaßt werden.
Method for quantitative determination of ochratoxin A in foods and feeds by means of High-pressure Liquid Chromatography (HPLC)
Summary A rapid, specific HPLC-method has been developed for quantitative determination of Ochratoxin A in food and feedstuffs as well as in mixed-feed.After preliminary clean-up of the McOH/Chloroform extract the ochratoxin is analyzed using HPLC with a Spherisorb S5 ODS column McOH/water/acetic acid as eluent and a fluorescence detector.The average recovery was about 50% in the range for 50–500 ppb with a small variation (coefficient of variation 10.24% and 23.650. The detection limit for Ochratoxin A is 5 ppb.相似文献
123.
124.
The European tooling industry is strongly as ever confronted with the turbulent global economic environment. As a sole focus
on price and technical feasibility does not lead to sustainable competitive advantages, toolmakers need to find new ways for
differentiation. A promising approach are industrial product service systems but the lack of local presence and the small
company sizes complicate the delivery of such services to global customers. Web-based collaboration platforms can link toolmakers
to build up a stable network of partners around the globe and help to maintain competitive advantages. These platforms include
toolmaker, tool user, tool owner and service provider for global service provision in the tooling industry. The concept of
this platform and their features are presented in this paper. 相似文献
125.
Grain boundary segregation has been established through both simulation and experiments as a successful approach to stabilize nanocrystalline materials against grain growth. However, relatively few alloy systems have been studied in this context; these vary in their efficacy, and in many cases the stabilization effect is compromised by second phase precipitation. Here we address the open-ended design problem of how to select alloy systems that may be stable in a nanocrystalline state. We continue the development of a general “regular nanocrystalline solution” model to identify the conditions under which binary nanocrystalline alloy systems with positive heats of mixing are stable with respect to both grain growth (segregation removes the grain boundary energy penalty) and phase separation (the free energy of the nanocrystalline system is lower than the common tangent defining the bulk miscibility gap). We calculate a “nanostructure stability map” in terms of alloy thermodynamic parameters. Three main regions are delineated in these maps: one where grain boundary segregation does not result in a stabilized nanocrystalline structure, one in which macroscopic phase separation would be preferential (despite the presence of a nanocrystalline state stable against grain growth) and one for which the nanocrystalline state is stable against both grain growth and phase separation. Additional details about the stabilized structures are also presented in the map, which can be regarded as a tool for the design of stable nanocrystalline alloys. 相似文献
126.
A mesoscale model, shear transformation zone dynamics (STZ dynamics), is employed to investigate the connections between the structure and deformation of metallic glasses. The present STZ dynamics model is adapted to incorporate a structure-related state variable, and evolves via two competing processes: STZ activation, which creates free volume, vs. diffusive rearrangement, which annihilates it. The dynamical competition between these two processes gives rise to an equilibrium excess free volume that can be connected to flow viscosity via the phenomenological Vogel–Fulcher–Tammann relation in relaxed structures near the glass transition temperature. On the other hand, the excess free volume allows glasses to deform at low temperatures via shear localization into shear bands, even in the presence of internal stress distributions that arise upon cooling after processing. 相似文献
127.
Compared the midterm grades of each of 86 business students to the grade the student gave the professor on his teaching effectiveness. A 1-way analysis of variance showed better than chance correspondence (h2 = .23). This tendency was entitled the animadversion error, and its importance in subordinate-supervisor ratings is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
128.
W. Hanle J. Fischer Ernst Witt D. Küchemann H. W. Hahnemann R. Schwarzenberger W. Kraus K. Lamberts H. Gebelein W. de Beauclair K. Wellinger H. Schuh I. M. Lorenz 《Forschung im Ingenieurwesen》1957,23(1-2):77-80
Ohne Zusammenfassung
VDI 相似文献
129.
Woo A.C. Wang H.T.G. Schuh M.J. Sanders M.L. 《Antennas and Propagation Magazine, IEEE》1992,34(6):52-56
In February, 1989, a Computational Electromagnetics (CEM) validation measurement program was initiated by the Electromagnetic Code Consortium (EMCC), to fabricate and test several small radar cross-section (RCS) range models, in order to generate RCS reference data for validating existing and future codes. As part of the validation effort, the EMCG defined various sets of three- and two-dimensional targets. Measured data are presented here for five of the 3D plate targets. They are a wedge-cylinder plate, a wedge-plate cylinder, a plate cylinder, a 2×3.5 λ flat plate, and a wedge-cylinder with a gap 相似文献
130.
We characterized the clinical dose-response curves for relief of parkinsonism and production of dyskinesias as a function of plasma levodopa and 3-O-methyldopa levels in six patients with advanced Parkinson's disease (PD) and fluctuating responses to oral levodopa/carbidopa. Dose response to ramped intravenous levodopa infusion was measured after overnight drug withdrawal on two occasions: first after chronic, intermittent oral levodopa/carbidopa, and second after 3 to 5 days of continuous intravenous levodopa. Continuous intravenous levodopa shifted the dyskinesia dose-response curve to the right, reduced maximum dyskinesia activity, but did not significantly alter dose response for relief of parkinsonism. Improvement in dyskinesia was apparent by the second day of continuous levodopa, during which ratios of plasma dopa/3-O-methyldopa remained constant. Our results support the hypothesis that relief of parkinsonism and production of dyskinesia by levodopa occur by separate mechanisms. 相似文献