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21.
The wavelet transform (WT) is used to represent all possible types of transients in vibration signals generated by faults in a gear box. It is shown that the transform provides a powerful tool for condition monitoring and fault diagnosis. The vibration signal of a spur bevel gear box in different conditions is used to demonstrate the application of various wavelets in feature extraction. In present work, a discrete wavelet, Daubechies wavelets (db1–db15) is used for feature extraction and their relative effectiveness in feature extraction is compared. The major steps in pattern classification are feature extraction and classification. This paper investigates the use of discrete wavelets for feature extraction and a Decision Tree for classification. J48 Decision Tree algorithm has been used for feature selection as well as for classification. This paper illustrates the powerfulness and flexibility of the discrete wavelet transform to decompose linear and non-linear processing of vibration signal. 相似文献
22.
Chen K Huzil JT Freedman H Ramachandran P Antoniou A Tuszynski JA Kurgan L 《Journal of molecular graphics & modelling》2008,27(4):497-505
Microtubules are involved in numerous cellular processes including chromosome segregation during mitosis and, as a result, their constituent protein, tubulin, has become a successful target of several chemotherapeutic drugs. In general, these drugs bind indiscriminately to tubulin within both cancerous and healthy cells, resulting in unwanted side effects. However, differences between beta-tubulin isotypes expressed in a wide range of cell types may aid in the development of anti-tubulin drugs having increased specificity for only certain types of cells. Here, we describe a digital signal processing (DSP) method that is capable of predicting hot spots for the tubulin family of proteins as well as determining relative differences in binding affinities to these hot spots based only on the primary sequence of 10 human tubulin isotypes. Due to the fact that several drug binding sites have already been characterized within beta-tubulin, we are able to correlate hot spots with the binding sites for known chemotherapy drugs. We have also verified the accuracy of this method using the correlation between the binding affinities of characterized drugs and the tubulin isotypes. Additionally, the DSP method enables the rapid estimation of relative differences in binding affinities within the binding sites of tubulin isotypes that are yet to be experimentally determined. 相似文献
23.
Cole JN Henningham A Gillen CM Ramachandran V Walker MJ 《Proteomics. Clinical applications》2008,2(3):387-410
Gram-positive streptococci are non-motile, chain-forming bacteria commonly found in the normal oral and bowel flora of warm-blooded animals. Over the past decade, a proteomic approach combining 2-DE and MS has been used to systematically map the cellular, surface-associated and secreted proteins of human pathogenic streptococcal species. The public availability of complete streptococcal genomic sequences and the amalgamation of proteomic, genomic and bioinformatic technologies have recently facilitated the identification of novel streptococcal vaccine candidate antigens and therapeutic agents. The objective of this review is to examine the constituents of the streptococcal cell wall and secreted proteome, the mechanisms of transport of surface and secreted proteins, and describe the current methodologies employed for the identification of novel surface-displayed proteins and potential vaccine antigens. 相似文献
24.
An experimental technique is presented to measure reflectance at high sample temperature with respect to room temperature in the infrared using Fourier transform infrared fitted with a reflectometer. Sample temperature artifacts are accounted for by sequential measurements taken with the lamp source on and with the lamp source off. The sequential measurements are shown mathematically to correct for the modulation of sample and detector thermal emissions. Further, the technique is applied to a polyimide (PMDA-ODA) film on a layer of gold deposited on a thermally oxidized Si wafer. It is shown that the optical properties (index of refraction and extinction coefficient) remain relatively constant with temperature (from room temperature to 380 degrees C) in the 4000-6000 cm(-1) spectral region. The significant changes that occur with temperature are the change in thickness of the film and also the spectral properties in the 2000-4000 cm(-1) region. Also, by using a Lorentz oscillator model, it is shown that this method is able to discern that spectral features corresponding to the OH stretching bands at 3630 and 3470 cm(-1) show significant variation with increasing temperature. 相似文献
25.
We review the literature on long memory ARFIMA and GARMA models andintroduce a new efficient estimator for GARMA models, which we show to berobust. Next we conduct a Monte Carlo study to demonstate the power of theDickie–Fuller test when the data are generated from a stationary GARMAprocess. We conclude with a brief discussion of cointegration in the contextof GARMA models with an application to international interest rates. 相似文献
26.
Probabilistic belief contraction has been a much neglected topic in the field of probabilistic reasoning. This is due to the difficulty in establishing a reasonable reversal of the effect of Bayesian conditionalization on a probabilistic distribution. We show that indifferent contraction, a solution proposed by Ramer to this problem through a judicious use of the principle of maximum entropy, is a probabilistic version of a full meet contraction. We then propose variations of indifferent contraction, using both the Shannon entropy measure as well as the Hartley entropy measure, with an aim to avoid excessive loss of beliefs that full meet contraction entails. 相似文献
27.
Using photo acoustic technique, the thermal properties of CdS thin films grown by spray pyrolysis are measured. Thermal diffusivity
and conductivity in these films decrease at least two orders compared with bulk. These results are compared with our study
on nano CdS and the other available literature. The comparison is good. The dependence of thermal diffusivity on the thickness
of the layer or the size of the particles on the glass substrate are analysed from the present measurement and discussed.
The dependence of thermal diffusivity on the thickness of the layer on the glass substrate is discussed. 相似文献
28.
Ligon W.B. III Ramachandran U. 《Parallel and Distributed Systems, IEEE Transactions on》1997,8(7):681-694
lnterconnection network design plays a central role in the design of parallel systems. Most of the previous research has evaluated the performance of interconnection networks in isolation. In this study, we investigate the relationship between application program characteristics and interconnection network performance using an execution driven simulation test bed: the Reconfigurable Architecture Workbench (RAW). We simulate five topological configurations of a k-ary n-cube interconnect and four different network link models for a 4,096 node SIMD machine, and quantify the impact of the network on two application programs. We provide experimental evidence that such “in-context” simulation provides a better view of the impact of network design variables on system performance. We show that recent results, indicating that low-dimensional designs provide better ICN performance, ignore application requirements that may favor high-dimensional designs. Furthermore, applications that would appear to favor low dimensional designs may not, in fact, be significantly impacted by the network's dimensionality. We experimentally test the results of published performance models comparing the use of a synthetic load to that of a load generated by a typical application program 相似文献
29.
M. Sivabarathy S. Natarajan S. K. Ramakrishnan K. Ramachandran 《Bulletin of Materials Science》2004,27(5):403-407
Phase transition in L-alaninium oxalate is studied by using TG, DTA and photoacoustic spectroscopy. A sharp transition at
378 K by photoacoustics is observed whereas at the same temperature the endothermic energy change observed by TG and DTA is
not very sharp. This is discussed in detail with reference to the other known data for the organic crystals. 相似文献
30.
The rapid growth of the robotic industry has made it imperative to consider more seriously the safety aspects of robotic installations. Some work has been initiated recently in this area; a standard proposed by the Robotic Industries Association is a step in the right direction. This paper is based on an investigation of the state of the art in robotic safety, and contains an analysis of the sources of accidents, and the accident-prone operational phases of robotic installations. It forms the groundwork (literature survey) of a research project at the University of Windsor to develop a hardware/software-based safety system. It is suggested that both the robot manufacturer and the user should regard robotic safety as an important consideration. 相似文献