轮胎硫化机微机自动跟踪控制软件的设计调试

本文介绍了轮胎硫化机微机自动跟踪控制软件的设计调试,包括辅机（后充气）软件的模块化设计思路、梯形图设计及生产试车。经实际使用证明,该控制软件克服了辅机原来控制上的传统隐患,可缩短设计和调试周期、缩短用户对设备的熟悉时间和维护时间,还为今后软件的修改提供了兼容性     

蒸汽透平转速下降的原因分析与处理措施

分析了循环氢压缩机产生转速下降故障的原因,并提出了故障的处理措施。     

Temperature Dependence of Electric‐induced Light Scattering Performance for PLZT Ceramics

PLZT (7.45/71/29) ceramics with fully dense microstructure and high transmittance were fabricated by a hot‐press sintering method. The effects of temperature on the phase structure, ferroelectric property, and electric‐induced light scattering performance of the PLZT ceramics were examined and analyzed. XRD patterns indicated that the PLZT sample tended to transform from rhombohedral phase to tetragonal phase with the temperature increasing. And the temperature‐dependent ferroelectric hysteresis behavior of the PLZT sample revealed the conversion of a saturated square hysteresis loop to a double‐loop‐like hysteresis loop, accompanied with the significant reduction in coercive field and remnant polarization. Depending on the temperature, the PLZT sample exhibited three different kinds of electric‐induced light scattering performance.     

3D QSAR Studies,Pharmacophore Modeling and Virtual Screening on a Series of Steroidal Aromatase Inhibitors

Aromatase inhibitors are the most important targets in treatment of estrogen-dependent cancers. In order to search for potent steroidal aromatase inhibitors (SAIs) with lower side effects and overcome cellular resistance, comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were performed on a series of SAIs to build 3D QSAR models. The reliable and predictive CoMFA and CoMSIA models were obtained with statistical results (CoMFA: q² = 0.636, r²_ncv = 0.988, r²_pred = 0.658; CoMSIA: q² = 0.843, r²_ncv = 0.989, r²_pred = 0.601). This 3D QSAR approach provides significant insights that can be used to develop novel and potent SAIs. In addition, Genetic algorithm with linear assignment of hypermolecular alignment of database (GALAHAD) was used to derive 3D pharmacophore models. The selected pharmacophore model contains two acceptor atoms and four hydrophobic centers, which was used as a 3D query for virtual screening against NCI2000 database. Six hit compounds were obtained and their biological activities were further predicted by the CoMFA and CoMSIA models, which are expected to design potent and novel SAIs.     

中国古代火腿及火腿肴馔概述

中国的火腿历史悠久,其制作方法也随着时代的前进而发展,用火腿制成的风味肴馔是中国饮食文化中的一朵奇葩。     

Nanoporous Al‐Ni‐Co‐Ir‐Mo High‐Entropy Alloy for Record‐High Water Splitting Activity in Acidic Environments

Ir‐based binary and ternary alloys are effective catalysts for the electrochemical oxygen evolution reaction (OER) in acidic solutions. Nevertheless, decreasing the Ir content to less than 50 at% while maintaining or even enhancing the overall electrocatalytic activity and durability remains a grand challenge. Herein, by dealloying predesigned Al‐based precursor alloys, it is possible to controllably incorporate Ir with another four metal elements into one single nanostructured phase with merely ≈20 at% Ir. The obtained nanoporous quinary alloys, i.e., nanoporous high‐entropy alloys (np‐HEAs) provide infinite possibilities for tuning alloy's electronic properties and maximizing catalytic activities owing to the endless element combinations. Particularly, a record‐high OER activity is found for a quinary AlNiCoIrMo np‐HEA. Forming HEAs also greatly enhances the structural and catalytic durability regardless of the alloy compositions. With the advantages of low Ir loading and high activity, these np‐HEA catalysts are very promising and suitable for activity tailoring/maximization.     

三元超导化合物Sc_5Ir_4Si_(10)的低温比热性质

在零场下2～300K以及不同磁场下2～10K温度范围内,分别测量了超导Sc5Ir4Si10单晶的比热。采用4-Einstein峰拟合声子谱的方法对高温部分进行处理,成功地分离了Sc5Ir4Si10的晶格比热和电子比热。10K以下的比热遵守经典的超导理论,即晶格比热与温度的三次方成正比,电子比热符合温度的幂指数关系。4K以下电子比热的磁场关系为ΔCe/T∝Hα,其中α与温度有关。随着温度的降低α的值从0.67增大到0.76,表明Sc5Ir4Si10的超导配对可能是s波和d波混合波,并由d波向s波转化。     

Fatty Acyl-CoA Reductase and Wax Synthase from <Emphasis Type="Italic">Euglena gracilis</Emphasis> in the Biosynthesis of Medium-Chain Wax Esters

Euglena gracilis, a unicellular phytoflagellate, can accumulate a large amount of medium-chain wax esters under anaerobic growth conditions. Here we report the identification and characterization of two genes involved in the biosynthesis of wax esters in E. gracilis. The first gene encodes a fatty acyl-CoA reductase (EgFAR) involved in the conversion of fatty acyl-CoAs to fatty alcohols and the second gene codes for a wax synthase (EgWS) catalyzing esterification of fatty acyl-CoAs and fatty alcohols, yielding wax esters. When expressed in yeast (Saccharomyces cerevisiae), EgFAR converted myristic acid (14:0) and palmitic acid (16:0) to their corresponding alcohols (14:0Alc and 16:0Alc) with myristic acid as the preferred substrate. EgWS utilized a broad range of fatty acyl-CoAs and fatty alcohols as substrates with the preference towards myristic acid and palmitoleyl alcohol. The wax biosynthetic pathway was reconstituted by co-expressing EgFAR and EgWS in yeast. When myristic acid was fed to the yeast, myristyl myristate (14:0–14:0), myristyl palmitoleate (14:0–16:1), myristyl palmitate (14:0–16:0) and palmityl myristate (16:0–14:0) were produced. These results indicate EgFAR and EgWS are likely the two enzymes involved in the biosynthesis of medium-chain wax esters in E. gracilis.