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151.
Given two processes, each having a total-ordered set ofn elements, we present a distributed algorithm for finding median of these 2n elements using no more than logn +O(logn) messages, but if the elements are distinct, only logn +O(1) messages will be required. The communication complexity of our algorithm is better than the previously known result which takes 2 logn messages. 相似文献
152.
Chun-Yuan Cheng Lassina Barro Shang-Ting Tsai Tai-Wei Feng Xiao-Yu Wu Che-Wei Chao Ruei-Siang Yu Ting-Yu Chin Ming Fa Hsieh 《International journal of molecular sciences》2021,22(6)
Microglia-mediated neuroinflammation is recognized to mainly contribute to the progression of neurodegenerative diseases. Epigallocatechin-3-gallate (EGCG), known as a natural antioxidant in green tea, can inhibit microglia-mediated inflammation and protect neurons but has disadvantages such as high instability and low bioavailability. We developed an EGCG liposomal formulation to improve its bioavailability and evaluated the neuroprotective activity in in vitro and in vivo neuroinflammation models. EGCG-loaded liposomes have been prepared from phosphatidylcholine (PC) or phosphatidylserine (PS) coated with or without vitamin E (VE) by hydration and membrane extrusion method. The anti-inflammatory effect has been evaluated against lipopolysaccharide (LPS)-induced BV-2 microglial cells activation and the inflammation in the substantia nigra of Sprague Dawley rats. In the cellular inflammation model, murine BV-2 microglial cells changed their morphology from normal spheroid to activated spindle shape after 24 h of induction of LPS. In the in vitro free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, EGCG scavenged 80% of DPPH within 3 min. EGCG-loaded liposomes could be phagocytized by BV-2 cells after 1 h of cell culture from cell uptake experiments. EGCG-loaded liposomes improved the production of BV-2 microglia-derived nitric oxide and TNF-α following LPS. In the in vivo Parkinsonian syndrome rat model, simultaneous intra-nigral injection of EGCG-loaded liposomes attenuated LPS-induced pro-inflammatory cytokines and restored motor impairment. We demonstrated that EGCG-loaded liposomes exert a neuroprotective effect by modulating microglia activation. EGCG extracted from green tea and loaded liposomes could be a valuable candidate for disease-modifying therapy for Parkinson’s disease (PD). 相似文献
153.
Thermal stability behaviors of Cr(N,O)/CrN double-layered coatings by TGA/DTA analysis 总被引:1,自引:0,他引:1
In this study, Cr(N,O)/CrN double-layered coatings were synthesized using the cathodic arc deposition (CAD) process. CrN film was first deposited onto a substrate as an interlayer to ensure better adhesion, and Cr(N,O) film was subsequently deposited on top of the CrN layer as the surface layer. Variation in the Cr(N,O) coating composition was achieved through changing the O2/N2 flow ratio during the last stage of processing. Phase structure, chemical composition, and morphology of the resulting coatings were analyzed and observed using the X-ray diffractometer, Auger electron spectrometer and SEM. In addition, oxidation behavior of the coatings was investigated using TGA/DTA methods. The tests were carried out by increasing temperature up to 1000 °C in ambient air. With the introduction of oxygen gas during the CAD process, a superficial layer was produced in the Cr(N,O) constituent containing CrN and Cr2O3 phases. The formation of the oxide phase attributed to the reaction of chromium and oxygen was more favorable than that of chromium and nitrogen. The results also showed that Cr(N,O)/CrN double-layered coatings exhibited superior oxidation resistance at elevated temperature than that of CrN single-layer coated specimen (870 °C vs. 750 °C). 相似文献
154.
High-speed milling of titanium alloys using binderless CBN tools 总被引:4,自引:0,他引:4
Z. G. Wang Y. S. Wong M. Rahman 《International Journal of Machine Tools and Manufacture》2005,45(1):105-114
The performance of conventional tools is poor when used to machine titanium alloys. In this paper, a new tool material, which is binderless cubic boron nitride (BCBN), is used for high-speed milling of a widely used titanium alloy Ti–6Al–4V. The performance and the wear mechanism of the BCBN tool have been investigated when slot milling the titanium alloy in terms of cutting forces, tool life and wear mechanism. This type of tool manifests longer tool life at high cutting speeds. Observations based on the SEM and EDX suggest that adhesion of workpiece and attrition are the main wear mechanisms of the BCBN tool when used in high-speed milling of Ti–6Al–4V. 相似文献
155.
Tool wear and chatter detection using the coherence function of two crossed accelerations 总被引:1,自引:0,他引:1
X.Q. Li Y.S. Wong A.Y.C. Nee 《International Journal of Machine Tools and Manufacture》1997,37(4):425-435
Tool wear and chatter have been found to be the main causes of rejects in the machining of super alloys. A novel detection technique to identify both tool wear and chatter in turning a nickel-based super alloy is introduced. It uses the coherence function between two crossed accelerations from the bending vibration of the tool shank. The value of the coherence function at the chatter frequency reaches unity at the onset of chatter. Its values at the first natural frequencies of the tool shank approach unity in the severe tool wear stage. The results are interpreted using the analysis of the coherence function for a single input-two output model. The advantage of using this method is that the thresholds for detecting severe tool wear and chatter can be easily set, since values of coherence function are normalized to a range of between zero and unity, and are also not so susceptible to changing cutting conditions, because the value of the coherence function is close to unity at the onset of chatter and severe tool wear. 相似文献
156.
The hydrodynamics of a two-dimensional gas–solid fluidized bed reactor were studied experimentally and computationally. Computational fluid dynamics (CFD) simulation results from a commercial CFD software package, Fluent, were compared to those obtained by experiments conducted in a fluidized bed containing spherical glass beads of 250– in diameter. A multifluid Eulerian model incorporating the kinetic theory for solid particles was applied in order to simulate the gas–solid flow. Momentum exchange coefficients were calculated using the Syamlal–O’Brien, Gidaspow, and Wen–Yu drag functions. The solid-phase kinetic energy fluctuation was characterized by varying the restitution coefficient values from 0.9 to 0.99. The modeling predictions compared reasonably well with experimental bed expansion ratio measurements and qualitative gas–solid flow patterns. Pressure drops predicted by the simulations were in relatively close agreement with experimental measurements at superficial gas velocities higher than the minimum fluidization velocity, Umf. Furthermore, the predicted instantaneous and time-average local voidage profiles showed similarities with the experimental results. Further experimental and modeling efforts are required in a comparable time and space resolutions for the validation of CFD models for fluidized bed reactors. 相似文献
157.
Woon Wong 《时间序列分析杂志》1997,18(2):181-194
A stationary multivariate time series { X t } is defined as linear if it can be written in the form X t = ∑∞ j =−∞ A j e t − j where A j are square matrices and e t are independent and identically distributed random vectors. If the e t } are normally distributed, then { X t is a multivariate Gaussian linear process. This paper is concerned with the testing of departures of a vector stationary process from multivariate Gaussianity and linearity using the bispectral approach. First the definition and properties of cumulants of random matrices are used to obtain the expressions for the higher-order cumulant and spectral vectors of a linear vector process as defined above. Then it is shown that linearity of a vector process implies constancy of the modulus square of its normalized higher-order spectra whereas the component of such a vector process does not necessarily have a linear representation. Finally, statistics for the testing of multivariate Gaussianity and linearity are proposed. 相似文献
158.
159.
Model epoxy and bismaleimide compounds in thin film form were used to simulate epoxy and bismaleimide composite surfaces, in order to study compositional changes and interfacial reactions induced by oxygen plasma treatment. X-ray photoelectron spectroscopy (XPS) and infrared reflection-absorption spectroscopy (IR-RAS) were used to probe chemical changes which occurred. XPS and IR-RAS were found to be complementary techniques in determining the nature of functional groups incorporated into surfaces by plasma treatment. IR-RAS analysis of the model surfaces following exposure to a liquid epoxy resin revealed that while adsorption of the liquid epoxy occurred on both plasma-treated and nonplasma-treated surfaces, the oxygen plasma-treated surface alone was capable of initiating ring-opening reactions in the epoxy. However, this effect was not observed unless immediate contact was made between the plasma-treated surface and the liquid epoxy resin, illustrating the short-lived reactivity of the functional groups on the plasma-treated surface. 相似文献
160.
A CF3‐containing diamine, 4,4′‐bis(4‐amino‐2‐trifluoromethylphenoxy)benzophenone ( 2 ), was synthesized from 4,4′‐dihydroxybenzophenone and 2‐chloro‐5‐nitrobenzotrifluoride. Imide‐containing diacids ( 3 and 5Ba – 5Bg ) were prepared by the condensation reaction of aromatic diamines and trimellitic anhydride. Then, two series of novel soluble aromatic poly(amide imide)s (PAIs; 6Aa – 6Ak and 6Ba – 6Bg ) were synthesized from a diamine ( 4Aa – 4Ak or 2 ) with the imide‐containing diacids ( 3 and 5Ba – 5Bg ) via direct polycondensation with triphenyl phosphate and pyridine. The aromatic PAIs had inherent viscosities of 0.74–1.76 dL/g. All of the synthesized polymers showed excellent solubility in amide‐type solvents, such as N‐methyl‐2‐pyrrolidone and N,N‐dimethylacetamide (DMAc), and afforded transparent and tough films by DMAc solvent casting. These polymer films had tensile strengths of 90–113 MPa, elongations at break of 8–15%, and initial moduli of 2.0–2.9 GPa. The glass‐transition temperatures of the aromatic PAIs were in the range 242–279°C. They had 10% weight losses at temperatures above 500°C and showed excellent thermal stabilities. The 6B series exhibited less coloring and showed lower yellowness index values than the corresponding 6A series. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102:3641–3653, 2006 相似文献