Intellectual deficits after transient tyrosinemia in the term neonate

An analysis was made of the obstetric history of 1,360 patients who were delivered in 1971. It involved 3,185 pregnancies. The aim of the study was to evaluate the risk of spontaneous termination of the pregnancy, worked out from its demographic aspect. Several ideas are worthy of consideration. The risk of spontaneous intra-uterine death is cumulative, sharply increased by a repetition of such cessation of pregnancy. The same patients often undergo intentional abortion repeatedly. The respective risks of spontaneous and provoked interruption of pregnancy have been studied in greater detail as a function of parity.     

Survey of impaired drivers, fatally injured or surviving, who caused fatal highway accidents in Alberta in 1970-72

In 1970-72, 456 (53.4%) of 854 drivers responsible for a motor vehicle accident in which either they or other persons were killed had been drinking beforehand. Of surviving culpable drivers tested for blood alcohol concentration 81.7% were found to be legally impaired; however, only 24.8% of these drivers were tested. Because surviving culpable drivers pose a possible future hazard to highway safety it is important that data on this group be collected and analysed.     

Very low birth weight children at school age: comparison of neonatal management methods

The outcome of 293 infants born to a geographically defined community and weighing 501-1500 g was investigated. Medical intervention in the newborn period had been avoided. Morbidity was assessed at school age. Of the infants, 236 had been live born in the labour ward of this hospital; of these, 117 (49.6%) died in the neonatal period, one (0.4%) died in the first year, four (1.7%) were untraced, 13 (5.5%) had major handicap, 29 (12.3%) had minor handicap, and 72 (30.5%) were considered to be normal. In terms of survival, handicap, and intellectual with that of infants born over the same period (1963-71) in areas where intensive methods of perinatal care were used. These results imply that postnatal survival and potential of infants of very low birth weight are by no means prejudiced when only experienced nursing care is available.     

Absence of tonic electromyographic activity during sleep in normal and spastic nonmimetic skeletal muscles in man

An electromyographic study of nonmimetic skeletal muscles was carried out in 8 normal adults and 4 patients with spastic hemiparesis during all stages of sleep for a total of 21 nights. All normal subjects showed absence of tonic electromyographic activity in all nonmimetic skeletal muscles in all stages of sleep. Also, during quiet, relaxed wakefulness, tonic muscle discharges disappeared in the normal subjects. Three patients with upper motor neuron spasticity demonstrated results during sleep similar to those obtained in the normal subjects. In the fourth patient, tonic muscle discharges persisted into stage 2 non-REM sleep, disappeared within 30 to 240 seconds following the onset of stage 2 sleep, and were absent during stages 3 and 4 sleep and REM sleep.     

The effect of phosphate treatment on nickel dispersion on MCM-41 mesoporous material

The incorporation of nickel into mesoporous molecular sieves MCM-41 was carried out. Ni-PO/MCM41 and Ni-C1/MCM41 were prepared by using Ni(II) acetate solution adjusted to pH=2.5 with phosphoric acid and hydrochloric acid, respectively, by the incipient wetness method. Photoacoustic spectroscopy (PAS) was used to study the local environments of Ni(II) incorporated into mesopores. The PAS of as-prepared Ni/MCM41, Ni-Cl/MCM41, and Ni-PO/MCM41 with Ni(II) acetate solution exhibits two bands of λ_max around 400 nm and 750 nm, which could be assigned to the³A_2g→³T_lg(F) and the³A_2g→³T_lg(P) transition of octahedral Ni(II) species. After calcination, Ni ion within Ni-PO/MCM41 dispersed atomically onto the surface of MCM-41 channel as an octahedral species without the transformation to nickel oxide phase, while Ni ion within Ni-Cl/MCM41 and Ni/MCM41 transformed to nickel oxide phase. It may be attributed to the fact that each Ni ion is separated by the phosphate grafted to surface silanol group. The effects of phosphoric acid on the dispersity of Ni ion within MCM-41 have been investigated using³¹P and²⁹Si MAS NMR spectroscopy and X-ray photoelectron spectroscopy.