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81.
In the aftermath of 9/11 events it became clear that the impact of a fast flying commercial airliner hitting the NPP could no longer be excluded as a potential external hazard threatening the nuclear power plant (NPP) safety. One of the potential consequences of the impact is the occurrence of a fireball, large enough to engulf the entire NPP. The knowledge about fireballs from air crashes is rather poor since it is only based on footage shot by chance. From careful physical and chemical examinations using first principles, it can be concluded that the physics and chemistry of the kerosene fireball are similar to BLEVE fireballs in gas tank accidents which have been studied during the last decades. The knowledge from these analyses can be applied to air crash fireball analysis.In order to obtain an adequate understanding of the potential hazards to a NPP engulfed by a fireball a detailed analysis of the fireball is necessary. It is only by a detailed analysis that the effect of the NPP structures on the evolution of the fireball can be derived. Though the safety-relevant parts of the NPP are strong concrete structures, according to IAEA regulations the hypothesized entry of combustion products into ventilation or air supply systems and the entry of fuel into buildings through normal openings have to be analyzed in detail. This requires local transient values of the safety-relevant fireball parameters. With the NPP being a very large structure an adequately detailed simulation requires large computing grids and substantial computing power.With the release of Version 5 of the Fire Dynamic Simulator (FDS) from NIST in 2007 a simulation tool is now available which is capable to perform simulations of large fireballs on sufficiently large computing grids. These fireball simulations can be performed also by any other CFD code in which the relevant models have been implemented.The FDS fireball simulation capabilities were validated with the help of a well-documented fireball event, in which 5.9 to of propane were burnt during a BLEVE impact experiment conducted by the German BAM in 1999.To demonstrate the applicability of FDS to nuclear safety analysis a simulation of the impact of a 90 to fireball on a generic NPP was performed. The results are presented in this paper and show that FDS release Version 5 is an adequate tool to analysis the effect of a fireball on a NPP, even if the largest possible amount of kerosene involved in the crash is assumed.The work presented in this paper is based on codes, papers, footage and material that are freely available on the Internet. The paper does not use any information that is not freely available on the Internet.  相似文献   
82.
The main assumption of existing efficient topography simulations is that sputtering is a local process that depends only on the angle of incidence and not on the detailed shape of the surface. If redeposition is considered, sputtered atoms are redeposited and cause no further sputtering when they hit another part of the surface. Furthermore the angular distribution of sputtered atoms follows a cosine law. If ion reflection is considered, ions do not lose energy during backscattering. Using binary collision simulations (IMSIL) and comparing them with results obtained by a topography simulator (IonShaper®) we show that all these assumptions need refinement for the simulation of nanostructures except the neglect of sputtering by sputtered atoms. In addition we show that a nonlocal model is essential for ion beam induced deposition of narrow structures.  相似文献   
83.
On forecasting large and infrequent snow avalanches   总被引:1,自引:0,他引:1  
Snow avalanches that threaten a highway or a residential area are often large avalanches that have a return period > 1 year. Danger assessment strongly relies on precipitation data since these avalanches are typically triggered by major snow storms. Given the extensive protection work that is in place in the European Alps, the avalanche control service (also called avalanche commission) responsible for danger assessment will usually monitor the avalanche situation throughout the winter, but only become active in case of a major snow fall. Related safety concepts describing the procedures and measures to be taken in a given danger situation are therefore often based on threshold values for new snow. By analysing the avalanche occurrence of a major avalanche path, we show that forecasting based on new snow amounts involves high uncertainty. Whereas the return period of an avalanche to, for example, the road was about 5 years, the return period for the corresponding new snow depth was substantially smaller, in our case slightly less than 2 years. Similar proportions were found for a number of other avalanche paths with different snow climate. The return period of the critical new snow depth was about 2–5 times smaller than the return period of the avalanche. This proportion is expected to increase with increasing return period. Hence, based on the return period of an avalanche path a first estimate for the critical new snow depth can be made. With a return period of the critical new snow depth of 1–2 years, avalanche prediction for individual avalanche path becomes very challenging since the false alarm ratio is expected to be high.  相似文献   
84.
Increased striatal dopamine D2 receptor activity is thought to contribute to the pathophysiology of schizophrenia. To model this condition in mice, Kellendonk et al. (2006) generated transgenic mice that selectively overexpress the D2 receptor in striatum (D2OE). Drew et al. (2007) reported that D2OE mice display deficits in interval timing and motivation. The present study further explored the impaired timing in D2OE mice. Experiment 1 assessed the role of motivation in producing timing deficits in the peak procedure and found that performance in D2OE mice was improved by increasing motivation. In addition, performance was impaired in control mice when motivation was decreased. In Experiment 2, we found that D2OE mice have no timing impairment when tested using the bisection task, a procedure in which the measure of timing performance is less influenced by motivation to respond. In Experiment 3, we also used the bisection task and found selective impairment in timing of long durations in D2OE mice. These results suggest that striatal D2 overexpression impairs timing by decreasing motivation and through its impact on working memory and/or sustained attention. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
85.
Using the results of a comprehensive data analysis of final energy consumption in industry and commercial buildings, the assessment has been made of the potential for gradual implementation of cogeneration plants in these facilities. In doing so, plans for the expansion of the natural gas pipeline distribution network in Thailand are taken into consideration. The sample comprises of 2540 factories and 1651 commercial buildings from which it was found that 817 factories and 966 commercial buildings were suitable for the implementation of natural gas-based cogeneration technologies until 2020. By the implementation of cogeneration in these facilities, it is possible to save 3.2% of the total primary energy consumption in Thailand in 2003.  相似文献   
86.
Water: A key resource in energy production   总被引:1,自引:0,他引:1  
Water and energy are the key resources required for both economic and population growth, and yet both are increasingly scarce. The distribution of water takes large amounts of energy, while the production of energy requires large amounts of water in processes such as thermal plant cooling systems or raw materials extraction. This study analyzes the water needs for energy production in Spain according to the energy source sector (electricity, transportation or domestic) and process type (extraction and refining of raw materials or thermal plant use). Current and future water needs are quantified according to energy demand and technology mix evolution. Hypothetical scenarios that simulate the risks of promoting specific energy policies are also analyzed. Results show that the combination of energy resources used in Spain is projected to be more than 25% more water consumptive in 2030 than in 2005 under ceteris paribus conditions. Renewable energies are mixed in terms of their consequences on the water supply; wind power can reduce water withdrawal, while the biofuels production is a water-intensive process.  相似文献   
87.
The role of fat content and type of surfactant for oral friction processes and texture perception of oil-in-water emulsions was assessed. Emulsions at 22% and 33% fat content containing either sodium caseinate or a sucrose ester as emulsifier were compared with viscosity-adapted aqueous solutions of dextran using both sensory evaluation and friction coefficient measurements on a tongue-palate contact model. The impact of saliva on the emulsion droplet size distribution was studied using tribology, differential interference contrast microscopy and light diffraction measurements. Emulsions at 33% and the corresponding iso-viscous aqueous solutions were discriminated in the sensory experiment whereas emulsions at 22% were not. Friction was significantly different for emulsions at 33% and the corresponding iso-viscous aqueous solutions. The difference was not significant for emulsions with 22% fat level when compared with the iso-viscous aqueous solutions. Saliva significantly decreased the friction coefficient of emulsions depending on the surfactant and amount of fat used.  相似文献   
88.
In Austria, using hydropower has a centuries-long tradition. Whereas we first placed mills along our rivers to put water’s power to use, today we have over 5,200 water power stations of various types, from the smallest facilities to pumped-storage hydroelectric plants in the Alps. Today, water power accounts for roughly 60 % of our domestic power production, though the various types of power stations used have diverse ecological effects. This article presents a “win-win” approach to improving both hydropower production and ecological outcomes on the basis of the Kamp River in Lower Austria. The Kamp is not only home to a pumped-storage hydroelectric plant and the major plants Ottenstein, Dobra-Krumberg and Thurnberg-Wegscheid, but also to 14 smaller plants with turbines that are between 25 and 75 years old, many of them with energy conversion efficiency ratios of well under 0.7. Using the case study of a small water power plant, the chances of achieving a win-win situation are presented in detail. In this context, replacing the turbines is a major aspect of improving these plants. Extensive analyses have demonstrated that balanced planning approaches can yield both higher efficiency and better conditions for aquatic ecology, thanks to increased residual flows. Further, energy calculations and numerical habitat simulations have confirmed that a win-win situation is feasible for the small power plant studied, especially if Kaplan turbines are used. For example, they show that, despite the increased residual flow of up to 800 l/s, a considerable performance increase over the status quo is possible (maximum performance increase of 17 % without considering residual flow). If the residual flow was only 400 l/s, which tests indicate would mean an improvement in the habitat conditions for all ages of the dominant fish species (the brown trout) of > 50 %, a performance increase of 8 % would be the result. Thanks to the generally applicable methodology used, the win-win approach presented here can broadly be used in the optimization, efficiency improvement and revitalization of current hydropower plants, producing both more electricity and higher residual flow levels to improve local ecological conditions. In order to make this win-win situation a reality, innovative and integrative financial models for e.g. new turbines related to the fields of green energy production and environmental protection will be essential.  相似文献   
89.
    
Genetically engineered mouse models have the potential to unravel fundamental biological processes and provide mechanistic insights into the pathogenesis of human diseases. We have previously observed that germline genetic variation at the TULP4 locus influences clinical characteristics in patients with myeloproliferative neoplasms. To elucidate the role of TULP4 in pathological and physiological processes in vivo, we generated a Tulp4 knockout mouse model. Systemic Tulp4 deficiency exerted a strong impact on embryonic development in both Tulp4 homozygous null (Tulp4−/−) and heterozygous (Tulp4+/−) knockout mice, the former exhibiting perinatal lethality. High-resolution episcopic microscopy (HREM) of day 14.5 embryos allowed for the identification of multiple developmental defects in Tulp4−/− mice, including severe heart defects. Moreover, in Tulp4+/− embryos HREM revealed abnormalities of several organ systems, which per se do not affect prenatal or postnatal survival. In adult Tulp4+/− mice, extensive examinations of hematopoietic and cardiovascular features, involving histopathological surveys of multiple tissues as well as blood counts and immunophenotyping, did not provide evidence for anomalies as observed in corresponding embryos. Finally, evaluating a potential obesity-related phenotype as reported for other TULP family members revealed a trend for increased body weight of Tulp4+/− mice.  相似文献   
90.
    
The rapid increase and spread of Gram-negative bacteria resistant to many or all existing treatments threaten a return to the preantibiotic era. The presence of bacterial polysaccharides that impede the penetration of many antimicrobials and protect them from the innate immune system contributes to resistance and pathogenicity. No currently approved antibiotics target the polysaccharide regions of microbes. Here, describe monolaurin-based niosomes, the first lipid nanoparticles that can eliminate bacterial polysaccharides from hypervirulent Klebsiella pneumoniae, are described. Their combination with polymyxin B shows no cytotoxicity in vitro and is highly effective in combating K. pneumoniae infection in vivo. Comprehensive mechanistic studies have revealed that antimicrobial activity proceeds via a multimodal mechanism. Initially, lipid nanoparticles disrupt polysaccharides, then outer and inner membranes are destabilized and destroyed by polymyxin B, resulting in synergistic cell lysis. This novel lipidic nanoparticle system shows tremendous promise as a highly effective antimicrobial treatment targeting multidrug-resistant Gram-negative pathogens.  相似文献   
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