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81.
Jürgen Schönbeçk 《NTM》2004,12(2):80-99
Thomas Fincke (January 6th, 1561–April 24th, 1656), born in Flensburg (Germany), was one of the very most important and significant scientists in Denmark during the
seventeenth century, a mathematician and astrologer and physician in the beginning of modern science, a representative of
humanism and an influentual academic organizer. He studied in Strasbourg (since 1577) and Padua (since 1583) and received
his M.D. in Basel (1587), he practised as a physician throughout his life (since 1587 or 1590) and became a professor at Copenhagen
(1591). But he was best known because of his Geometriae rotundi libri XIIII (1583), a famous book on plane and spherical trigonometry, based not on Euclid but on Petrus Ramus. In this influentual work,
in which Fincke introduced the terms tangent and secant and probable first noticed the Law of Tangents and the so-called Newton-Oppel-Mauduit-Simpson-Mollweide-Gauss-formula,
he showed himself to be „abreast of the mathematics of his time“.
相似文献
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83.
Modeling mechatronic multibody systems requires the same type of methodology as for designing and prototyping mechatronic
devices: a unified and integrated engineering approach. Various formulations are currently proposed to deal with multiphysics
modeling, e.g., graph theories, equational approaches, co-simulation techniques. Recent works have pointed out their relative
advantages and drawbacks, depending on the application to deal with: model size, model complexity, degree of coupling, frequency
range, etc. This paper is the result of a close collaboration between three laboratories, and aims at showing that for “non-academic”
mechatronic applications (i.e., issuing from real industrial issues), multibody dynamics formulations can be generalized to
mechatronic systems, for the model generation as well as for the numerical analysis phases. Model portability being also an
important aspect of the work, they must be easily interfaced with control design and optimization programs. A global “demonstrator”,
based on an industrial case, is discussed: multiphysics modeling and mathematical optimization are carried out to illustrate
the consistency and the efficiency of the proposed approaches. 相似文献
84.
Larynx-associated lymphoid tissue (LALT) in young children 总被引:1,自引:0,他引:1
A Kracke AS Hiller T Tschernig M Kasper WJ Kleemann HD Tr?ger R Pabst 《Canadian Metallurgical Quarterly》1997,248(3):413-420
BACKGROUND: Mucosa-associated lymphoid tissue (MALT) plays a central role in mucosal immunity. Whereas the characteristics and function of MALT in the intestine are well established, almost nothing is known about MALT in the larynx. METHODS: In this study we examined the morphology and the lymphocyte subset composition of MALT in the larynges of children who had died of sudden infant death or various defined traumatic or nontraumatic causes. RESULTS: Organized lymphoid tissue was found in the supraglottic parts of the larynx in nearly 80% of the children in both groups. This lymphoid tissue showed all morphological signs of MALT, such as typical lymphoid follicles with germinal centers, infiltration of the overlying epithelium by lymphocytes, and high endothelial venules (HEV). Thus we will use the term LALT (larynx-associated lymphoid tissue) to refer to this tissue. The lymphoid follicles of LALT contained mainly B lymphocytes with some CD4+ lymphocytes in the germinal centers. Remarkably, T lymphocytes of both subset types and B lymphocytes were observed in comparable numbers in the parafollicular area. CONCLUSIONS: We assume that LALT is a physiological structure of the larynx in young children. The morphology and the distribution of lymphocyte subsets are similar to those of MALT in the human gut. LALT may be a regular part of the mucosal immune system in young children with the role of respiratory inductive site for mucosal immunity. 相似文献
85.
OBJECTIVE: To investigate the efficacy of the rectus abdominis muscle flap (RAMF) technique for the closure and augmentation of small, non-compliant bladder exstrophies. PATIENTS AND METHODS: The RAMF technique was used in two girls and two boys (mean age at operation, 31.7 months, range 3-72) with bladder exstrophy. The clinical outcome and urodynamics were assessed during a follow-up of 29 months to 6 years (mean 49.2 months) and included imaging, cystoscopy, biochemical and microbiological studies. RESULTS: There were no urinary tract infections, metabolic problems or electrolyte disturbances and kidney function remained normal in all patients. Radiography confirmed intact function and anatomy of the urinary tract and cystoscopy showed complete coverage of the inner peritoneal layer of RAMF with uroepithelium. No stone formation or mucus production were detected. Currently, three patients void using clean intermittent catheterization through the native urethra and the fourth through an appendiceal Mitrofanoff valve. However, the bladder volume was insufficient at the late follow-up and three patients required bladder augmentation. CONCLUSIONS: The RAMF technique is a good alternative for closing bladder exstrophies and achieves an increase in bladder capacity; however, although there is a mild improvement in bladder capacity and compliance. RAMF should not be used as a bladder augmentation procedure. The technique is indicated in the closure of large bladder defects, bladder exstrophies with small, inelastic, non-compliant bladder remnants and failed primary closures. 相似文献
86.
87.
P Kn?bl G Schernthaner C Schnack P Pietschmann A Griesmacher R Prager M Müller 《Canadian Metallurgical Quarterly》1993,36(10):1045-1050
Parameters of haemostasis, endothelial cell markers and lipid peroxide levels were studied in 64 Type 1 (insulin-dependent) and 94 Type 2 (non-insulin-dependent) diabetic patients according to their urinary albumin excretion rate in comparison with age-matched control subjects. We determined plasma levels of fibrinogen (Clauss' method), coagulation factor VII:activity (clotting assay), factor VII antigen, protein C and S antigen, von Willebrand factor antigen, D-dimer concentration (ELISA), and lipid peroxide levels (thiobarbituric acid) in relation to urinary albumin excretion rate (RIA). Significant positive correlations were found between urinary albumin excretion rate and plasma fibrinogen (p < 0.005, p < 0.02), factor VII activity (p < 0.0002, p < 0.002), factor VII antigen (p < 0.0001, p < 0.001), protein C (p < 0.003, p < 0.05), and lipid peroxides (p < 0.02, p < 0.004) in Type 1 as well as in Type 2 diabetes. Von Willebrand factor (p < 0.001) and protein S (p < 0.0005) correlated with albuminuria only in patients with Type 1 diabetes. Although most of the haemostatic abnormalities are already found in normoalbuminuric patients, the significant positive correlations to urinary albumin excretion indicate that endothelial cell damage and coagulation disorders deteriorate with the progression of diabetic nephropathy. 相似文献
88.
89.
E Kievit FB van Gog HM Schlüper GA van Dongen HM Pinedo E Boven 《Canadian Metallurgical Quarterly》1997,38(4):813-823
The effects of arginine vasopressin (AVP) and oxytocin (OT) upon thyroid-stimulating hormone (TSH), free thyroxine (FT4) and free triiodothyronine (FT3) release were studied in euthyroid rats. Intracerebroventricular (i.c.v.) infusion of AVP in doses of 0.5 ng or 5 ng led to significant increases in plasma levels of TSH as well as FT4 and FT3. The effects of OT injected i.c.v. in similar doses were not consistent (there was no parallel between the changes of respective hormones plasma levels). It may be concluded that vasopressin modulate the pituitary-thyroid system function; AVP is probably a physiological stimulator of TSH and thyroid hormones secretion. 相似文献
90.