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31.
Sedimentation superimposed on industrial cake filtration leads to longer filtration times and often has a detrimental effect on subsequent process steps such as washing and demoisturing. The influence of sedimentation is seldom recognised in laboratory filtration experiments. Methods are presented for evaluation of pressure filter experiments with superimposed sedimentation which avoid the error made in the usual evaluation methods. For the case of zone sedimentation the article presents a graphical evaluation and a numerical method of modelling permitting scale up to any desired cake height. In superimposed classifying sedimentation simultaneous measurement of filtrate volume and cake height provide information about local variation in filter cake resistance. It is shown for a model system that, owing to sedimentation, the cake resistance shows a minimum at mean cake height and increases rapidly towards greater heights. The local cake resistance corelates with particle size distributions measured for layers of a horizontally cut filter cake. The method of evaluation presented permints determination of the flow resistance of the uppermost layers of a cake and hence estimation of the gas pressure necessary for demoisturing. The profiles of local filter cake resistance show that the relative cake layering is largely independent of the level of suspension filling. A scale-up model is presented for use in those cases where classifying sedimentation cannot be suppressed.  相似文献   
32.
Microscopic compression tests (micropillar tests) are typically used to obtain stiffness and strength properties of materials at small length scales. In this work it is shown that structural effects, in particular instabilities, have implications on the resulting load–displacement diagram. Care has to be taken when the measured load–displacement path of a micropillar is interpreted as a stress–strain path of the material. Several structural effects are discussed by means of computational analysis.  相似文献   
33.
In this study, three asset management strategies were compared with respect to their efficiency to reduce flood risk. Data from call centres at two municipalities were used to quantify urban flood risks associated with three causes of urban flooding: gully pot blockage, sewer pipe blockage and sewer overloading. The efficiency of three flood reduction strategies was assessed based on their effect on the causes contributing to flood risk. The sensitivity of the results to uncertainty in the data source, citizens' calls, was analysed through incorporation of uncertainty ranges taken from customer complaint literature. Based on the available data it could be shown that increasing gully pot blockage is the most efficient action to reduce flood risk, given data uncertainty. If differences between cause incidences are large, as in the presented case study, call data are sufficient to decide how flood risk can be most efficiently reduced. According to the results of this analysis, enlargement of sewer pipes is not an efficient strategy to reduce flood risk, because flood risk associated with sewer overloading is small compared to other failure mechanisms.  相似文献   
34.
In order to reduce design-cycle time and physical prototyping, equipment manufacturers need to ascertain the thermal performance of new systems at the earliest possible stage of the design process. In the early 1990s, some European industries began to realize that the accurate prediction of the temperatures of critical electronic parts at the package, board, and system levels was seriously hampered by a lack of reliable, standardized input data that characterize the thermal behavior of these parts. It was the start of a number of European projects concerned with the creation and experimental calibration of thermal models for a range of electronic parts. The ultimate goal of these projects was to get component manufacturers to supply calibrated compact thermal models (CTMs) of their parts to end users by adopting the experimental techniques used to calibrate the detailed thermal conduction models of the parts and the methods to generate compact models. This review paper is written with the purpose of presenting a condensed overview of the history, background, philosophy, methodology, and standardization aspects of compact thermal modeling to non-experts. Some space is devoted to the basic concepts of thermal resistance and thermal characterization because many designers have an incorrect perception of the physics underlying these concepts.  相似文献   
35.
Osteo-inductive materials give rise to ectopic bone formation in vivo either in muscles or in subcutaneous tissue. However, the underlying molecular mechanism is totally unclear. To investigate the expression pattern of bone related genes in osteo-inductive materials, we performed quantitative PCR (qPCR) to detect the expressions of type I collagen, alkaline phosphatase (ALP) and bone morphogenetic protein 4 (BMP-4) in biphasic calcium phosphate (BCP) ceramics implanted in dorsal muscle of dogs. Bone formation in mandibular alveolus defects served as controls showing the expression patterns of these genes in natural healing bones. Histological examinations were performed to show the bone formation in osteo-inductive BCP implants. Data of qPCR indicated that all tested genes had a similar expression pattern with two peaks during the bone formation either in BCP implants or natural healing bones. Type I collagen and ALP were expressed at lower levels with delayed peak in BCP implant than that in natural healing bone. Higher BMP-4 expression level was detected in BCP ceramic implant than in natural healing bone at all the time points. These results demonstrated that expression patterns of bone-related genes in the inductive bone formation are similar to that of natural healing bone formation. As these three genes are important parameters for osteoblast activity in bone formation, our data provide clue to uncover the molecular mechanism of bone formation in osteo-inductive materials.  相似文献   
36.
For almost 30 years it has been known that compositional (closed) data have special geometrical properties. In environmental sciences, where the concentration of chemical elements in different sample materials is investigated, almost all datasets are compositional. In general, compositional data are parts of a whole which only give relative information. Data that sum up to a constant, e.g. 100 wt.%, 1,000,000 mg/kg are the best known example. It is widely neglected that the “closure” characteristic remains even if only one of all possible elements is measured, it is an inherent property of compositional data. No variable is free to vary independent of all the others.Existing transformations to “open” closed data are seldom applied. They are more complicated than a log transformation and the relationship to the original data unit is lost. Results obtained when using classical statistical techniques for data analysis appeared reasonable and the possible consequences of working with closed data were rarely questioned. Here the simple univariate case of data analysis is investigated. It can be demonstrated that data closure must be overcome prior to calculating even simple statistical measures like mean or standard deviation or plotting graphs of the data distribution, e.g. a histogram. Some measures like the standard deviation (or the variance) make no statistical sense with closed data and all statistical tests building on the standard deviation (or variance) will thus provide erroneous results if used with the original data.  相似文献   
37.
    
Indium tin oxide (ITO) is a transparent conducting material that is widely used in devices where high transparency of the electrodes is required, such as flat panel and liquid crystal displays, touch panels, smart windows, and many others. ITO layers are deposited on a large scale by magnetron sputtering and then structured by lithography to define desired patterns of transparent electrodes. Here, a method for direct printing of transparent conductive patterns from ITO nanoparticle ink is communicated. The method combines inkjet printing with fast flash lamp annealing whereby the main novelty is to use an additional layer of a colored organic dye onto printed ITO to increase light absorption. The dye coating is instantly heated together with the underlying ITO layer by a light pulse, leading to an instant rise of the surface temperature, which is translated into improved optoelectronic properties of the ITO layers. Inkjet‐printed ITO patterns processed with the dye‐assisted flash lamp annealing exhibit a transmittance of up to 88% at 550 nm and resistivity of 3.1 × 10−3 Ω cm. Transparent touch‐sensing trackpad and capacitive touch sensors are demonstrated based on the printed ITO patterns, which can be utilized in transparent security systems and other transparent Internet‐of‐Things devices.  相似文献   
38.
    
Recently developed stem-cell-based in vitro models of morphogenesis can help shed light on the mechanisms involved in embryonic patterning. These models are showcased using traditional cell culture platforms and materials, which allow limited control over the biological system and usually do not support high-content imaging. In contrast, using advanced microengineered tools can help in microscale control, long-term culture, and real-time data acquisition from such biological models and aid in elucidating the underlying mechanisms. Here, a new culturing, manipulation and analysis platform is described to study in vitro morphogenesis using thin polycarbonate film-based microdevices. A pipeline consisting of open-source software to quantify 3D cell movement using 4D image acquisition is developed to analyze cell migration within the multicellular clusters. It is shown that the platform can be used to control and study morphogenesis in non-adherent cultures of the P19C5 mouse stem cell line and mouse embryonic stem cells (mESCs) that show symmetry breaking and axial elongation events similar to early embryonic development. Using the new platform, it is found that localized cell proliferation and coordinated cell migration result in elongation morphogenesis of the P19C5 aggregates. Further, it is found that polarization and elongation of mESC aggregates are dependent on directed cell migration.  相似文献   
39.
    
By combining X‐ray and ultraviolet photoelectron spectroscopy, X‐ray excited Auger electron spectroscopy, and inverse photoemission spectroscopy, a detailed characterization of the chemical and electronic structure at the CdTe/(Zn,Mg)O interface is presented. In doing so, a novel approach to characterize the electronic structure of transparent conductive oxides, namely, to distinguish between optically and transport‐relevant states is presented. Consequently, “optical” and “electronic” band offsets at the CdTe/(Zn,Mg)O interface are derived and it is demonstrated that the “electronic” band offset is suitable for electron transport across the interface (a flat conduction band alignment of 0.02 ± 0.20 eV), while the “optical band offset” is not (a significant 0.48 ± 0.20 eV spike). The new approach can easily be applied to many other transparent conductive oxides and is thus of relevance for a large variety of optoelectronic applications involving transparent electrical contacts.  相似文献   
40.
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