Radical Scavenging Activity and LC-MS Metabolic Profiling of Petals, Stamens, and Flowers of Crocus sativus L

Radical scavenging activities of Crocus sativus petals, stamens and entire flowers, which are waste products in the production of the spice saffron, by employing ABTS radical scavenging method, were determined. At the same time, the metabolic profiles of different extract (obtained by petals, stamens and flowers) were obtained by LC-ESI-IT MS (liquid chromatography coupled with electrospray mass spectrometry equipped with Ion Trap analyser). LC-ESI-MS is a techniques largely used nowadays for qualitative fingerprint of herbal extracts and particularly for phenolic compounds. To compare the different extracts under an analytical point of view a specific method for qualitative LC-MS analysis was developed. The high variety of glycosylated flavonoids found in the metabolic profiles could give value to C. sativus petals, stamens and entire flowers. Practical Application: Waste products obtained during saffron production, could represent an interesting source of phenolic compounds, with respect to the high variety of compounds and their free radical scavenging activity.     

Chemical and antifungal investigations of six Lippia species (Verbenaceae) from Brazil

The Lippia genus is used in ethnobotany as food, beverages, seasoning and antiseptic remedies, among others. The chemical compositions of fifteen extracts of six Lippia species were investigated comparatively by HPLC-PDA. To avoid data replication of previous works on this genus, Lippia lupulina Cham. root ethanol extract was selected for isolation procedures based on Principal Component Analyses (PCA) of such data. Seven compounds previously unreported in this genus were isolated from this extract (a triterpene, two furanonaphtoquinones, a furanochromone, an isoflavone, a stilbene and an iridoid). The activities of extracts, fractions and pure compounds towards Candida albicans, Candida krusei, Candida parapsilosis and Cryptococcus neoformans were investigated. Two fractions from the extract of Lippia salviaefolia leaves showed marked inhibition of fungal growth, in addition to verbascoside and asebogenin, which showed MICs lower than 15.6μg/ml and may be promising leads for the development of new antifungal agents, especially against C. neoformans.     

Liquid crystalline elastomers based on diglycidyl terminated rigid monomers and aliphatic acids. Part 2. Mechanical characterization

In this paper the orientational behaviour and the mechanical properties of four LC elastomers, obtained by reacting two mesogenic epoxy monomers, DOMS and PHBHQ, with two aliphatic acids having four (AA) and eight (SA) methylene groups, respectively, have been studied.Stress-relaxation experiments performed at a strain value ε=0.2 showed shorter relaxation times and lower relaxation moduli for AA-based elastomers as compared with the PHBHQ-SA system.Stress-strain curves of the LC elastomers showed the plateau attributed to the soft elasticity. The lower crosslink density in the case of DOMS-based elastomers affected the tensile properties adversely. Moreover, PHBHQ-SA was found to show poor strain recovery and it recovered the original size only upon heating to isotropic phase. This evidence was also confirmed by isostrain measurements.Dynamic mechanical thermal analysis (DMTA) confirmed the existence of a heterogeneous, more branched structure in the case of DOMS-based systems. The particular features of the DMTA response strongly depend on the material composition and, in general, were found in agreement with other evidences from the literature.     

Randomized circle detection with isophotes curvature analysis

Circle detection is a critical issue in image analysis and object detection. Although Hough transform based solvers are largely used, randomized approaches, based on the iterative sampling of the edge pixels, are object of research in order to provide solutions less computationally expensive. This work presents a randomized iterative work-flow, which exploits geometrical properties of isophotes in the image to select the most meaningful edge pixels and to classify them in subsets of equal isophote curvature. The analysis of candidate circles is then performed with a kernel density estimation based voting strategy, followed by a refinement algorithm based on linear error compensation. The method has been applied to a set of real images on which it has also been compared with two leading state of the art approaches and Hough transform based solutions. The achieved results show how, discarding up to 57% of unnecessary edge pixels, it is able to accurately detect circles within a limited number of iterations, maintaining a sub-pixel accuracy even in the presence of high level of noise.     

Waste and Virgin LDPE/PET Blends Compatibilized with an Ethylene‐Butyl Acrylate‐Glycidyl Methacrylate (EBAGMA) Terpolymer, 1

Summary: This work is aimed at studying the morphology and the mechanical properties of blends of low density polyethylene (LDPE) and poly(ethylene terephthalate) (PET) (10, 20, and 30 wt.‐% of PET), obtained as both virgin polymers and urban plastic waste, and the effect of a terpolymer of ethylene‐butyl acrylate‐glycidyl methacrylate (EBAGMA) as a compatibilizer. LDPE and PET are blended in a single screw extruder twice; the first extrusion to homogenize the two components, and the second to improve the compatibilization degree when the EBAGMA terpolymer is applied. Scanning electron microscopy (SEM) analysis shows that the fractured surface of both the virgin polymer and the waste binary blends is characterized by a gross phase segregation morphology that leads to the formation of large PET aggregates (10–50 µm). Furthermore, a sharp decrease in the elongation at break and impact strength is observed, which denotes the brittleness of the binary blends. The addition of the EBAGMA terpolymer to the binary LDPE/PET blends reduces the size of the PET inclusions to 1–5 µm with a finer dispersion, as a result of an improvement of the interfacial adhesion strength between LDPE and PET. Consequently, increases of the tensile properties and impact strength are observed.

SEM micrographs of the fracture surface of a waste 70/30 LDPE/PET blend (R30) and of its blend with 15 pph of EBAGMA (R30C). Magnification × 1 000.     

Isothermal and nonisothermal crystallization of HDPE composites containing multilayer carton scraps as filler

The influence of multilayer carton scraps (MC) on crystallization kinetics of high-density polyethylene (HDPE) is detailed in this contribution. HDPE/MC composites were prepared by melt mixing, and a maleated linear low density polyethylene (MAPE) was added as compatibilizer. The crystallization kinetics of HDPE/MC/MAPE was analyzed as function of composition both in isothermal and nonisothermal conditions. The multilayer carton scraps appear to promote the onset of crystallization of HDPE, acting as efficient nucleating agent. The presence of MAPE as compatibilizer slightly reduces the nucleating efficiency of MC: the compatibilizer induces a delay in the onset of crystallization, caused by the need to exclude the bulky pendant groups of maleated linear low-density polyethylene from the crystals, as HDPE and MAPE chains cocrystallize. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012     

Optimization models for computer data storage design: An application

In this paper we discuss a model being used to optimize the system design of the Computer Centre of one of the most important Italian banking groups. Data and transactions, processed by the system, are grouped respectively in data sets and by type, so it is possible to deal with the large dimensions of the corresponding optimization models. The transactions' arrivals are considered as stochastic variables and their probability values are estimated on the base of theoretical considerations. The solutions for two optimization problems, constructed and solved for different scenarios, are discussed in detail.     

Consideration on a case of carcinoma ex pleomorphic adenoma of the parotid gland

The authors report a case of carcinoma in an ex pleomorphic adenoma of the parotid gland that was recently referred to their attention. This form of carcinoma is not very frequent and in the literature it is reported in a percentage of cases ranging from 1.5 to 12%. The pathogenesis of this neoplasia is controversial and at the present state of the art there are authors who support the hypothesis of a malignant transformation of a previous pleomorphic adenoma, and those who sustain the onset of the tumour ex novo. At present, there is a tendency to differentiate the carcinoma ex pleomorphic adenoma from the malignant mixed tumour: the histological analysis of the former in fact shows a benign stromal component typical of pleomorphic adenoma associated with a malignant epithelial component, whereas in the malignant mixed tumour both the mesenchymal and epithelial components are malignant. The authors use this case report as a starting point to review their 20-year experience, of pleomorphic adenoma in order to evaluate the behaviour of this tumour, above all in relation to the phenomenon of recidivation and cancerization. They report recidivation in 3.5% of cases and no malignant degeneration. The surgical approach used varied depending on the site and size of the neoformation, as well as on whether the tumour was primary or recurrent.     

Investigation of hafnium-aluminate alloys in view of integration as interpoly dielectrics of future Flash memories

In this paper, we evaluate the potentialities of hafnium-aluminates (HfAlO) materials as possible candidates for the interpoly dielectrics of future Flash memory devices. HfAlO layers of different thicknesses and compositions are integrated in single-layers and in Oxide/HfAlO/Oxide (OHO) triple-layer stacks, and analyzed in terms of coupling and insulating capabilities. We demonstrate that increasing the Hf content allows reducing the leakage current at high voltages but it results in a stronger leakage current at low voltages. We also show that once normalized in electric fields, the leakage current characteristics are independent of the high-k thickness. The electron conduction modes in these materials, at different temperatures, are also investigated. The activation energy increases with the Hf concentration in the HfAlO alloy, resulting in a higher leakage current at elevated temperatures. Finally, it is demonstrated that the conduction in triple-layer stacks is limited by a Poole–Frenkel conduction in the high-k layers, while the trap contribution in the case of single-layers becomes dominant when the HfAlO layer is thicker than 8 nm.