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991.
With the development of science and technology, more and more large moving components have been used in industry, and their service lives have become an important issue. After analysis of the previous results, considering the scale factor, a prediction method for fatigue life of large moving components based on the Basquin relation was proposed at first, and then the magnet pole part of motor‐generator rotor was chosen to make simulation parts with different scale factors mainly in terms of their S‐N curves and fractographies. It was found that with the change of specimen scale factor, the stress concentration factor at transition arc is almost unchanged as well as the fatigue strength exponent, and the fatigue strength coefficient changes linearly. Based on those results, a life prediction method was validated, and the results show that this method is a simple but more precise relation. After fatigue fracture surface and crack growth angle observations and quantitative analyses, the fatigue damage mechanisms associated with the relation among fatigue strength exponent and coefficient and scale factors were explained well. Those studies will provide a new clue to the prediction of the service life for those large moving components.  相似文献   
992.
Smoking is a risk factor for a variety of deleterious conditions, such as cancer, respiratory disease and cardiovascular disease. Thrombosis is an important and common aspect of several cardiovascular disease states, whose risk is known to be increased by both first- and secondhand smoke. More recently, the residual cigarette smoke that persists after someone has smoked (referred to as thirdhand smoke or THS) has been gaining more attention, since it has been shown that it also negatively affects health. Indeed, we have previously shown that 6-month exposure to THS increases the risk of thrombogenesis. However, neither the time-dependence of THS-induced thrombus formation, nor its sex dependence have been investigated. Thus, in the present study, we investigated these issues in the context of a shorter exposure to THS, specifically 3 months, in male and female mice. We show that the platelets from 3-month THS-exposed mice exhibited enhanced activation by agonists. Moreover, we also show that mice of both sexes exposed to THS have decreased tail bleeding as well as decreased thrombus occlusion time. In terms of the role of sex, intersex disparities in thrombus development and hemostasis as well as in platelet aggregation were, interestingly, observed. Together, our findings show that exposing mice to THS for 3 months is sufficient to predispose them to thrombosis; which seems to be driven, at least in part, by an increased activity in platelets, and that it does not manifest equally in both sexes.  相似文献   
993.
Cysteine oxidation states of extracellular proteins participate in functional regulation and in disease pathophysiology. In the most common inherited dementia, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), mutations in NOTCH3 that alter extracellular cysteine number have implicated NOTCH3 cysteine states as potential triggers of cerebral vascular smooth muscle cytopathology. In this report, we describe a novel property of the second EGF-like domain of NOTCH3: its capacity to alter the cysteine redox state of the NOTCH3 ectodomain. Synthetic peptides corresponding to this sequence (NOTCH3 N-terminal fragment 2, NTF2) readily reduce NOTCH3 N-terminal ectodomain polypeptides in a dose- and time-dependent fashion. Furthermore, NTF2 preferentially reduces regional domains of NOTCH3 with the highest intensity against EGF-like domains 12–15. This process requires cysteine residues of NTF2 and is also capable of targeting selected extracellular proteins that include TSP2 and CTSH. CADASIL mutations in NOTCH3 increase susceptibility to NTF2-facilitated reduction and to trans-reduction by NOTCH3 produced in cells. Moreover, NTF2 forms complexes with the NOTCH3 ectodomain, and cleaved NOTCH3 co-localizes with the NOTCH3 ectodomain in cerebral arteries of CADASIL patients. The potential for NTF2 to reduce vascular proteins and the enhanced preference for it to trans-reduce mutant NOTCH3 implicate a role for protein trans-reduction in cerebrovascular pathological states such as CADASIL.  相似文献   
994.
A simple damage model with the concept of mode‐II microcracks on crack wall contributing to the irreversible strains for concrete is developed. By applying the micromechanics method, a microcell‐based damage model is introduced to understand the damage behaviour. Further, by introducing the physical interpretation of the damage variable using thermodynamic method, a novel damage variable (irreversible‐damage variable) is proposed to describe the irrecoverable strains generated by both mode‐II microcracks and irreversible‐frictional sliding. With this methodology, a simple continuum damage mechanics model is developed in which both elastic and irreversible damages are considered. As demonstrated by the comparison with experimental results, the proposed model is characterized by accuracy of solutions, sufficiency of physical sense and convenience of implementation.  相似文献   
995.
Dry-processed wastepaper (magazine) fibers possess desirable mechanical characteristics as reinforcing fibers in cement-based matrices; up to 50% of virgin wood fibers have been replaced with wastepaper fibers in cement composites without any significant change in short-term performance characteristics. The large volumes of fibrous cement board used in building construction promise to provide wastepaper with a large-volume and high-value application. In this study, the effects of weathering on the performance of recycled wastepaper fiber-cement composites were investigated through accelerated aging tests simulating natural aging conditions. Microstructural studies were conducted in order to establish the mechanisms of aging in the composite material. These mechanisms provided the basis for the selection of certain refinements in the matrix composition, which were successfully evaluated for the control of weathering effects on the composite material structure and properties. The effects of aging and moisture on composites were best controlled by measures which reduced the calcium hydroxide content of hydration products and improved the watertightness and the structure of interface zones; these refinements were made using relatively high levels of cement replacement with silica fume or through full substitution of Portland cement with a special cement.  相似文献   
996.
A nano-mechanical model has been developed to calculate the tensile modulus and the tensile strength of randomly oriented short carbon nanotubes (CNTs) reinforced nanocomposites, considering the statistical variations of diameter and length of the CNTs. According to this model, the entire composite is divided into several composite segments which contain CNTs of almost the same diameter and length. The tensile modulus and tensile strength of the composite are then calculated by the weighted sum of the corresponding modulus and strength of each composite segment. The existing micro-mechanical approach for modeling the short fiber composites is modified to account for the structure of the CNTs, to calculate the modulus and the strength of each segmented CNT reinforced composites. Multi-walled CNTs with and without inter-tube bridging have been considered. Statistical variations of the diameter and length of the CNTs are modeled by a normal distribution. Simulation results show that CNTs inter-tube bridging, length and diameter affect the nanocomposites modulus and strength. Simulation results have been compared with the available experimental results and the comparison concludes that the developed model can be effectively used to predict tensile modulus and tensile strength of CNTs reinforced composites.  相似文献   
997.
Arc-evaporated CrN, CrN and CrCN coatings   总被引:2,自引:0,他引:2  
The results of investigations of some tribological properties of chromium nitride, carbonitride and carbide films, prepared by cathodic arc-evaporation method (CAE) are presented in this article. The chemical composition of films was determined by the WDXs and EDXs. The different carbon content was obtained by using nitrogen and acetylene mixtures of various concentrations as the deposition atmosphere. The carbon content was ranging from 0 to 53 at.%. The adhesion of CrCN films was estimated from the analysis of scratch-test results comprising tangential (friction) force, acoustic emission and morphology of scratch surface. The films showed very good adhesion to steel substrates, expressed by Lc (critical load) value, as high as 90 N for carbon free films. The Lc decreased slightly as the carbon content increased. The hardness of films was investigated as a function of carbon content and was estimated by Jönsson-Hogmark method. The Lc value and hardness seem to be correlated in the same way with carbon content. The highest hardness (30 GPa) was obtained for CrN films, while carbon rich films (CrC) showed hardness at the level of 20 GPa. The tribological tests were performed in the ball-on-disk geometry in room air under the load of 1 N and 10 N. The wear rate of investigated films increased with carbon content above 20 at.%. The maximum value of the friction coefficient was 0.55, the same as for CrN films. It decreased to 0.33 as the carbon content increased.  相似文献   
998.
In order to facilitate product realisation processes, presently, research is actively being carried out to develop methodologies and technologies to support geographically dispersed teams to organise collaborative design based on the quickly evolving information technologies. A number of research works and commercial systems have appeared to provide solutions for collaborative and distributed product development, and the practical applications are getting more pervasive and mature. In this paper, the recently related works are summarised from three aspects—visualisation-based collaborative systems, co-design collaborative systems and CE (concurrent engineering)-based collaborative systems. Around these aspects, about 100 papers and 30 commercial systems/international standards published or launched recently are discussed. The current research and development statuses and issues, underlying algorithms, mechanisms and system architectures, and the future trends and challenges are explained and compared in detail.  相似文献   
999.
Ion implantation is a powerful method for fabricating nanoparticles in dielectric.For the actual application of nanoparticle composites,a careful control of nanoparticles has to be achieved.In this letter,the size,distribution and morphology of Ag nanoparticles are controlled by controlling the ion current density,ion implantation sequence and ion irradiation dose.Single layer Ag nanoparticles are formed by Ag+ion implantation at current density of 2.5μA/cm2.By Ag and Cu ions sequential implantation,the siz...  相似文献   
1000.
Selective laser melting technology is used to manufacture porous and solid AZ91D alloys. The effects of laser power and hatch spacing on the density, blowholes, microstructure and mechanical properties of AZ91D alloy are studied. The laser power and hatch spacing play a significant role in the density and blowholes of AZ91D specimens. The grains size of specimens increases from 1 μm–2 μm to 8 μm–10 μm from the bottom to the top in single molten pool. Compared with grain size of die‐casting alloy (30 μm), that of selective laser melted gets refinement. There is no significant change in microstructure in the bottom, middle and top of specimens. The micro‐hardness of AZ91D alloy, reaching up to 115.3 HV 0.1, is superior to that of die‐casting alloy (56 HV 0.1). The compression properties of porous and solid specimens reach the degree of die‐casting solid magnesium alloy. AZ91D alloy shows the potential in the application of medical biodegradable materials.  相似文献   
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