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581.
Rushikesh Battulwar Masoud Zare-Naghadehi Ebrahim Emami Javad Sattarvand 《岩石力学与岩土工程学报(英文版)》2021,13(4):920-936
In the last two decades, significant research has been conducted in the field of automated extraction of rock mass discontinuity characteristics from three-dimensional (3D) models. This provides several methodologies for acquiring discontinuity measurements from 3D models, such as point clouds generated using laser scanning or photogrammetry. However, even with numerous automated and semi-automated methods presented in the literature, there is not one single method that can automatically characterize discontinuities accurately in a minimum of time. In this paper, we critically review all the existing methods proposed in the literature for the extraction of discontinuity characteristics such as joint sets and orientations, persistence, joint spacing, roughness and block size using point clouds, digital elevation maps, or meshes. As a result of this review, we identify the strengths and drawbacks of each method used for extracting those characteristics. We found that the approaches based on voxels and region growing are superior in extracting joint planes from 3D point clouds. Normal tensor voting with trace growth algorithm is a robust method for measuring joint trace length from 3D meshes. Spacing is estimated by calculating the perpendicular distance between joint planes. Several independent roughness indices are presented to quantify roughness from 3D surface models, but there is a need to incorporate these indices into automated methodologies. There is a lack of efficient algorithms for direct computation of block size from 3D rock mass surface models. 相似文献
582.
Anjana Soorajkumar Ebrahim Alakraf Mohammed Uddin Stefan S. Du Plessis Alawi Alsheikh-Ali Richard K. Kandasamy 《International journal of molecular sciences》2022,23(15)
Short linear motifs (SLiMs) are short linear sequences that can mediate protein–protein interaction. Mimicking eukaryotic SLiMs to compete with extra- or intracellular binding partners, or to sequester host proteins is the crucial strategy of viruses to pervert the host system. Evolved proteins in viruses facilitate minimal protein–protein interactions that significantly affect intracellular signaling networks. Unfortunately, very little information about SARS-CoV-2 SLiMs is known, especially across SARS-CoV-2 variants. Through the ELM database-based sequence analysis of spike proteins from all the major SARS-CoV-2 variants, we identified four overriding SLiMs in the SARS-CoV-2 Omicron variant, namely, LIG_TRFH_1, LIG_REV1ctd_RIR_1, LIG_CaM_NSCaTE_8, and MOD_LATS_1. These SLiMs are highly likely to interfere with various immune functions, interact with host intracellular proteins, regulate cellular pathways, and lubricate viral infection and transmission. These cellular interactions possibly serve as potential therapeutic targets for these variants, and this approach can be further exploited to combat emerging SARS-CoV-2 variants. 相似文献
583.
Menas Ebrahim Eissa Mohamed Abdel Azim Mohamed Maher Ata 《International Journal of Communication Systems》2023,36(13):e5517
The number of internet users and connected devices has dramatically expanded due to the recent technological boom and the benefits that the internet of things offers to ease our lives. Network scheduling, quality of service, resource allocation, and security issues are now being addressed via software-defined networking (SDN). SDN has several benefits over traditional networks, including global centralized control, managing network traffic, and separating the forwarding and control plane. The work done in this paper aims to design and implement a traffic-aware routing framework based on routing optimization presented as an integer linear programming (ILP) to improve heterogeneous traffic flows' quality of service (QoS) in a simulated SDN environment. With the knowledge that the routing problem is a nondeterministic polynomial-time-hard problem, the proposed scheme aims to decrease the computational routing time to make the ILP-based routing system more suitable for real-time processing. The simulation results illustrate that the proposed framework reduces the computational time by 23% and 49% for Abilene and Goodnet topology, respectively. Additionally, with 1000 flows in the network, the suggested scheme reduces the number of network flows that violate the QoS by 9% and 22% (with Abilene topology) and 16% and 51% (with Goodnet topology) as compared to the existing shortest path delay and sway methods, respectively. 相似文献