Meat quality in pigs subjected to minimal preslaughter stress

The experiment compared meat quality in carcasses from pigs subjected to the absolute minimum of stress preslaughter with that from carcasses of pigs subjected to simulated commercial handling. A total of 120 pigs (85 kg) were used. They were a commercial hybrid and were processed in six equal batches. The minimal stress group were slaughtered with as little stress as possible. The simulated commercial handling group were mixed and transported for 2hr (80 km) and lairaged for 30 min. Simulated commercial handling increased plasma cortisol, plasma lactate, CPK and beta-endorphin. Muscle temperature measured in the m. longissimus dorsi (LD) at 45 min increased as did the ultimate pH in the m. adductor (AD). Overall eating quality was not affected. There were batch affects on most variables. Males were leaner and produced meat that had greater abnormal fat odour, darker cooked colour, poorer pork flavour, lower overall acceptability and was tougher.     

Flash pyrolysis of coals: behaviour of three coals in a 20 kg h−1 fluidized-bed pyrolyser

Flash pyrolysis of Loy Yang brown coal, and Liddell and Millmerran bituminous coals has been studied using a fluidized-bed reactor with a nominal throughput of 20 kg h^?1. The apparatus and its performance are described. The yields of tar and hydrocarbon gases are reported for each coal in relation to pyrolysis temperature, as also are analytical data on the pyrolysis products. The peak tar yields for the dry, ash-free Loy Yang and Millmerran coals were respectively 23% wt/wt (at ≈ 580 °C) and 35% wt/wt (at $\text{\$}\text{?}$600 °C). The tar yield from Liddell coal was 31% wt/wt at ≈ 580 °C. Hydro-carbon gases were produced in notable quantities during flash pyrolysis; e.g. Millmerran coal at 810 °C gave 6% wt/wt (daf) methane, 0.9% wt/wt ethane, 6% wt/wt ethylene, and 2.5% wt/wt propylene. The atomic $\text{H}\text{C}$ ratios and the absolute levels of hydrogen in product tars and chars decreased steadily with increasing pyrolysis temperature.     

Water quality of Scottish rivers: spatial and temporal trends

The Harmonised Monitoring Scheme (HMS) was initiated in 1974 and represents the best-organised source of temporal and spatial data describing water quality for the major mainland rivers of Scotland, England and Wales. This paper presents the first detailed analysis of HMS data for Scotland, and identifies temporal changes in water quality from 1974 to 1995. From a concomitant analysis of catchment land cover characteristics, water quality indices have been linked with potential 'drivers' of change, influencing both point and diffuse sources. Nitrate concentrations between rivers are highly correlated with the amount of arable land, and relationships exist between grassland cover, orthphosphate-P and suspended solids concentrations. Similarly, urban catchments are highly correlated with ammonium-N, orthophosphate-P and suspended solids. Spatial and temporal trends in water quality for the rivers of Scotland are discussed.     

Condom use by South African construction workers

Consistent and proper condom use is pivotal in preventing HIV infection. HIV prevalence in South Africa is among the highest in the world, with the construction industry especially affected, yet little is known about condom use by construction workers and the determinants thereof. Data were gathered from 512 site-based workers in the Western Cape. A theoretical model explaining condom use as a function of demographic factors, HIV knowledge, substance usage and risky sexual behaviour (excluding condom use) was proposed and tested using regression and structural equations modelling. The findings indicated that age, gender and level of education were indirect determinants of condom use, with higher levels of education predicting better AIDS-related knowledge. Higher levels of risky sexual behaviour were associated with more frequent use of condoms, suggesting greater awareness of risk. Condom use was adversely affected by greater alcohol and drug use, probably as a result of diminished capacity to assess risk. Finally, lower and not higher levels of AIDS-related knowledge were associated with better condom use, suggesting that improved knowledge of HIV transmission may work contrary to safe sex practice if it lulls the person into a false sense of confidence. Recommendations for targeted workplace interventions are proposed.     

Improving the energy production of roof-top solar PV systems through roof design

Building Simulation - Australia is receiving an average of 58 million PJ of solar radiation per year, which is about 1000 times larger than its total energy generation. Roof-top solar photovoltaic...     

Collaboration barriers in BIM-based construction networks: A conceptual model

Building information modelling (BIM) teams, hereafter referred to as BIM-based construction networks, are teams whose possibly geographically dispersed members from various organisations and disciplines, perform project tasks on BIM-enabled projects. In recent years, BIM-based construction networks have progressively become the norm in executing BIM activities on projects. However, even though achieving BIM's full capabilities relies on effective collaboration among the team members in BIM-based construction networks, it is still a struggle for these members to collaborate. Nonetheless, only a few studies have been conducted to identify the barriers to strengthening team collaboration in BIM-based construction networks. To address this gap, the current study, by examining 73 journal articles on collaboration in BIM-based construction networks, builds upon a theoretical review of the literature. A conceptual model is presented to capture the main barriers to collaboration in BIM-based construction networks. The study benefits researchers as well as project managers. For researchers, the conceptual model provides an intermediate theory, namely, a theoretical basis to direct further knowledge creation attempts on the topic. In addition, the conceptual model supports project managers on BIM-enabled projects. That is, it simplifies the knowledge now available for practical applications enabling it to be translated into guidelines and practical instructions on real-life projects.     

Perceived effectiveness of filial therapy for a Jamaican mother: A qualitative case study.

Although filial therapy has traditionally been viewed as suitable for children of diverse cultures, there is limited research to support this perspective. This qualitative case study examined the perceived effectiveness of filial therapy for a Jamaican mother and the perceived effect on the mother-child relationship. Findings indicate that some aspects of filial therapy are congruent with the parenting practices and values of this Jamaican mother. The mother reported an increase in empathy, a heightened awareness of her child's needs, and a stronger relationship with her child. She expressed some difficulty with limit setting and tracking skills taught as part of the model. Future research directions include further examination of the compatibility of filial therapy with other Jamaican parents and the effectiveness of group filial therapy with Jamaican parents or other parents of Caribbean descent. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Comparison of the chronic toxicity of piroxantrone, losoxantrone and doxorubicin in spontaneously hypertensive rats

We have determined the time course, the spatial spread in brain tissue, and the intracellular distribution of biotin- and fluorescein-labeled phosphorothioate oligodeoxynucleotides (ODNs) following single injections into the rat striatum or the lateral ventricle. These time and space parameters were correlated with the ability of c-fos phosphorothioate antisense ODNs to suppress the induction of Fos protein by cocaine. A rapid and dose-dependent tissue penetration of labeled ODNs was observed following either intrastriatal or intraventricular injections of a constant sample volume. Inspection of tissue sections by confocal microscopy uncovered a distinct change in the intracellular disposition of labeled ODNs during the 24 h post-injection period. At 1, 6 and 12 h, the vast majority of the fluorescent signal was confined to the interstitial spaces throughout the zone penetrated by ODNs. Neuronal nuclei displayed faint labeling along the outer portion of the nucleus at 1 and 6 h post-injection. At these time-points, ODNs were not detected in the cytoplasm. By 16 h, ODNs were barely detectable in the extracellular space and absent from neuronal nuclei. Instead, ODNs were seen in large cytoplasmic granules of neurons throughout the tissue zone penetrated by the ODNs. Experiments with intrastriatal injections of antisense ODNs to c-fos mRNA revealed Fos suppression between 3 and 12 h, but not at 16 and 24 h. This combined analysis has revealed that (1) restricted tissue penetration by ODNs limits their antisense effects on protein expression, and (2) depletion of extracellular ODNs and sequestration of c-fos antisense ODNs into large intracellular granules coincides with the loss of their biological activity.     

The antitumour activity of the prodrug N-L-leucyl-doxorubicin and its parent compound doxorubicin in human tumour xenografts

The antitumour activity of the investigational agent N-L-leucyl-doxorubicin (Leu-DOX) was compared with that of doxorubicin (DOX) in human tumour xenografts growing subcutaneously in athymic nude mice. Leu-DOX was developed as a prodrug of DOX, and may be converted into the clinically active parent compound by hydrolytic enzymes present in or on tumour cells. It has been suggested that a better therapeutic index with a reduced cardiac toxicity and higher efficacy might be obtained. Both compounds were administered intravenously weekly for 2 weeks, each at maximum tolerated doses of 8 mg/kg and 28 mg/kg for DOX and Leu-DOX, respectively. The panel of xenografts represented three different tumour types. Leu-DOX showed antitumour activity, defined as tumour growth inhibition > 50% and specific growth delay > 1.0, in 10 of the 16 tumours, including two of five breast, five of seven small cell and three of four non-small cell lung carcinomas. In comparison, DOX was active in one breast, four small cell lung and two lung adenocarcinoma xenografts. In all the DOX sensitive lung tumours, Leu-DOX showed higher efficacy than the parent compound. Based on the results of the present study, and since phase I clinical trials with Leu-DOX have already been performed, phase II clinical evaluation of Leu-DOX in patients with breast and lung cancer is recommended.