Riskmanagement und IT-Sicherheit

FORUM / RISKMANAGEMENT

Riskmanagement und IT-Sicherheit     

Analysis in ultrasmall volumes: microdispensing of picoliter droplets and analysis without protection from evaporation

A new approach is reported for analysis of ultrasmall volumes. It takes advantage of the versatile positioning of a dispenser to shoot approximately 150-pL droplets of liquid onto a specific location of a substrate where analysis is performed rapidly, in a fraction of the time that it takes for the droplet to evaporate. In this report, the site where the liquid is dispensed carries out fast-scan cyclic voltammetry (FSCV), although the detection method does not need to be restricted to electrochemistry. The FSCV is performed at a microcavity having individually addressable gold electrodes, where one serves as working electrode and another as counter/pseudoreference electrode. Five or six droplets of 10 mM [Ru(NH(3))(6)]Cl(3) in 0.1 M KCl were dispensed and allowed to dry, followed by redissolution of the redox species and electrolyte with one or five droplets of water and immediate FSCV, demonstrating the ability to easily concentrate a sample and the reproducibility of redissolution, respectively. Because this approach does not integrate detection with microfluidics on the same chip, it simplifies fabrication of devices for analysis of ultrasmall volumes. It may be useful for single-step and multistep sample preparation, analyses, and bioassays in microarray formats if dispensing and changing of solutions are automated. However, care must be taken to avoid factors that affect the aim of the dispenser, such as drafts and clogging of the nozzle.     

BCI Competition 2003--Data set Ia: combining gamma-band power with slow cortical potentials to improve single-trial classification of electroencephalographic signals

In one type of brain-computer interface (BCI), users self-modulate brain activity as detected by electroencephalography (EEG). To infer user intent, EEG signals are classified by algorithms which typically use only one of the several types of information available in these signals. One such BCI uses slow cortical potential (SCP) measures to classify single trials. We complemented these measures with estimates of high-frequency (gamma-band) activity, which has been associated with attentional and intentional states. Using a simple linear classifier, we obtained significantly greater classification accuracy using both types of information from the same recording epochs compared to using SCPs alone.     

2W reliable operation of λ=735 nm GaAsP/AlGaAs laser diodes

Reliable operation of 735 nm laser diodes based on a tensile-strained GaAsP quantum well embedded in an AlGaAs large optical cavity structure is reported. The 100 μm stripe width laser diodes were aged at a record high output power of 2W for 2000 hours. The degradation rates were 3.6×10^-5 h^-1     

Vorgespannte Decken ohne schlaffe Bewehrung

Pre‐stressed slabs without reinforcing steel The method of pre‐stressing concrete members was developed in the 1930's and the positive effect of pre‐stressing on the reduction of deflections and cracks was recognised at the time. The impressive developments in bridge construction methods in the course of the 20^th century could only be achieved by employing pre‐stressing. The advantages of using the pre‐stressing method in building constructions are exploited in a few countries, e. g. Australia and USA but not so much and not to the same extent in European countries. This paper shows, that it is feasible to build post‐tensioned slabs without reinforcing steel and points out a method that makes the construction of concrete slabs more economical.     

Erneuerung der abgehängten Decke in der Olympiaschwimmhalle in München

Renovation of the suspended roof of the Olympic Swimming Pool in Munich. The Olympic Swimming Pool being part of the Munich Olympic Facilities was built for the 1972 Olympic Summer Games. After more than 30 years the structural integrity and the thermal behaviour of the suspended membrane ceiling reached a critical stage. The following article describes the history of the suspended roof. It covers architectural, structural and thermal demands in its original state as well as the redesign and execution of the new, recently finished membrane ceiling.     

Chip-based multimodal super-resolution microscopy for histological investigations of cryopreserved tissue sections

Histology involves the observation of structural features in tissues using a microscope. While diffraction-limited optical microscopes are commonly used in hist...     

Preparation and characterization of copper indium diselenide films by electroless deposition

The preparation of copper indium diselenide (CIS) films by electroless deposition technique is reported. The films have been deposited on molybdenum substrates. The deposition bath consisted of aqueous solutions of copper chloride, indium chloride, selenous acid and lithium chloride. The pH of the bath was adjusted to 2.2 by adding dilute HCl. The Mo substrate was short-circuited with the aluminum counter electrode for the electroless deposition. The films have been characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDXA), inductively coupled plasma spectroscopy (ICP), Auger electron spectroscopy (AES) and optical spectroscopy. The results indicate that reasonable quality CIS films can be grown by simple electroless deposition process followed by recrystallization in selenium atmosphere.     

Highly Stereoselective Synthesis of Novel Multistereogenic Bis‐Bifunctional Ligands Based on [2.2]Paracyclophane‐ 4,7‐quinone,their Structure Elucidation and Application in Asymmetric Catalysis

Bis‐bifunctional cis‐4,7‐diarylsubstituted‐4,7‐dihydroxy‐4,7‐dihydro[2.2]paracyclophanes 3–6 were synthesized by a highly diastereoselective reaction of ortho‐substituted aryllithium reagents with [2.2]paracyclophane‐4,7‐quinone ( 1 ). Enantiomerically pure diols 3–5 were tested as chiral inductors in the enantioselective addition of diethylzinc to benzaldehyde (up to 93.5% ee). Acid dehydration of cis‐4,7‐di(2‐methoxyphenyl)‐4,7‐dihydroxy‐4,7‐dihydro[2.2]paracyclophane ( 3 ) results in 4,7‐dihydro‐7,8‐di(2‐methoxyphenyl)[2.2]paracyclophane‐4‐one ( 8 ) – a planar chiral cyclohexadienone of the [2.2]paracyclophane series with a para‐semiquinoid substructure. X‐Ray investigations of compounds 3, 4 and 8 were performed.     

MOVPE growth of AlGaAs/GaInP diode lasers

GaAs-based diode lasers for emission wavelengths between 800 nm and 1060 nm with AlGaAs-cladding and GaInP-waveguide layers were grown by MOVPE. For wavelengths above 940 nm broad area devices with InGaAs QWs show state-of-the-art threshold current densities. Ridge-waveguide lasers fabricated by selective etching achieve 200 mW CW monomode output powers. (In)GaAsP QW-based diode lasers with an emitting wavelengths around 800 nm suffer from problems at the upper GaInP/AlGaAs interface. Asymmetric structures with a lower AlGaAs/GaInP and an upper AlGaAs/AlGaAs waveguide not only avoid this interface but also offer better carrier confinement. Such structures show very high slope efficiencies and a high T₀. Maximum output powers of 7 W CW are obtained from 4 mm long devices.