A 90-nm CMOS, 8-bit pipeline ADC with 60-MHz bandwidth and 125-MS/s or 250-MS/s sampling frequency

In this paper a dual operating mode 8-bit, 1.1-V pipeline ADC for Gigabit Ethernet applications is presented. In the two operating modes, the ADC features different sampling frequency (125 and 250 MHz) and power consumption (9.4 and 22.8 mW). Considering a signal bandwidth of 60 MHz in both operating modes, as required by the Gigabit Ethernet standard, the ADC achieves a SNDR always larger than 39.4 dB at 125 MHz and 38.7 dB at 250 MHz (6.25-bit and 6.13-bit ENOB, respectively), with a FoM of 0.84 pJ/conv at 125 MHz and 2.2 pJ/conv at 250 MHz. The ENOB achieved is mainly limited by clock jitter. The ADC is fabricated with a 90-nm CMOS technology, with an active area of 1.25 × 0.65 mm².     

Heterogeneous Wireless Networks: Configuration and Vertical Handoff Management

Vertical handoff is one of the most important issues for the next generation heterogeneous wireless networks. However, in many situations, unbeneficial vertical handoffs occur across intersystem heterogeneous networks cause network performance degradation. Therefore, we propose a novel configuration architecture that can be deployed in the next generation of wireless networks. Second, we propose a predictive and adaptive Vertical Handoff Decision Scheme that optimizes the handoff initiation time as well as selection of the most optimal network. The proposed vertical handoff decision algorithm considers the technology type as well as the Signal to Interference Ratio (SIR), the Mobile Station (MS) velocity, the user preferences, the applications requirements and the terminal capabilities as the most important factors to make vertical handoff decision. In order to minimize handoff costs, the proposed decision algorithm uses the dwell timer concept. The handoff costs are analyzed in terms of unnecessary and unbeneficial handoffs rate.The simulation results show that the reduction of unnecessary handoffs proposed in our vertical handoff decision scheme reduces the handoff blocking probability, the packets loss rate and the handoff overhead     

A 5000 h RF life test on 330 W RF-LDMOS transistors for radars applications

A reliability test bench dedicated to RF power devices is used to improve 330 W LDMOS in a radar conditions. The monitoring of RF power, drain, gate voltages and currents under various pulses and temperatures conditions are investigated. Numerous duty cycles are applied in order to stress LDMOS. It shows with tracking all this parameters that only few hot carrier injection phenomenon appear with no incidence on RF figures of merit (P_out or PAE). Robustness and ruggedness are shown for LDMOS with this bench for radar applications in L-band.     

Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies

The objective of this project was to study the interaction between HR1 and HR2, the stability of the complex formed, and to characterize the antibodies produced against monomeric HR1 and HR2 peptides as well as the HR1-HR2 complex. In this work, HR1 was mimicked by peptide N36, and HR2 was mimicked by peptide C34L and its analogues C34M2, C34M3, and C34D. Whereas C34M2 and C34M3 are partially composed of D-amino acids, C34D has same sequence as C34L, but is assembled entirely of D-amino acids. Using CD analysis, SPR assays, and gel filtration chromatography, we demonstrate the physical interaction between N36 and C34L and its analogues C34M2 and C34M3, but not C34D. We show that the HR1-HR2 complex is formed rapidly (<1?min) and remains stable, as demonstrated by its inability, in contrast to each free peptide, to inhibit the formation of syncytia. To generate antibodies with predetermined specificity against the transiently exposed intermediate that corresponds to the six-helix bundle structure, purified preformed HR1-HR2 complex was used, in parallel with monomeric HR1 and HR2 peptides, as immunogens in mice. Although the produced antibodies recognize total HIV-1 envelope glycoproteins in ELISA, they are unable to neutralize HIV-1-mediated fusion at 37?°C. However, if the incubation with these antibodies is carried out at 27?°C, a temperature that allows stabilization of the transient intermediate complex, anti-peptide antibodies are able to bind their corresponding domains in HeLa cells expressing HIV-1 gp41 in co-culture with HeLa CD4-CCR5/CXCR4 during the dynamic mechanism of membrane fusion. In agreement with the latter results, these antibodies, if previously incubated for 2?h at 27?°C, are able to strongly neutralize HIV-1 entry by membrane fusion, as shown by their ability to block the formation of syncytia.     

CuII Pyrazolyl-Benzimidazole Dinuclear Complexes with Remarkable Antioxidant Activity

Three dinuclear coordination complexes generated from 1-n-butyl-2-((5-methyl-1H-pyrazole-3-yl)methyl)-1H-benzimidazole ( L ), have been synthesized and characterized spectroscopically and structurally by single crystal X-ray diffraction analysis. Reaction with iron(II) chloride and then copper(II) nitrate led to a co-crystal containing 78 % of [Cu(NO₃)(μ-Cl)( L’ )]₂ ( C₁ ) and 22 % of [Cu(NO₃)(μ-NO₃)( L’ )]₂ ( C₂ ), where L was oxidized to a new ligand L^’ . A mechanism is provided. Reaction with copper chloride led to the dinuclear complex [Cu(Cl)(μ-Cl)( L) ]₂ ( C₃ ). The presence of N−H⋅⋅⋅O and C−H⋅⋅⋅O intermolecular interactions in the crystal structure of C₁ and C₂ , and C−H⋅⋅⋅N and C−H⋅⋅⋅Cl hydrogen bonding in the crystal structure of C₃ led to supramolecular structures that were confirmed by Hirshfeld surface analysis. The ligands and their complexes were tested for free radical scavenging activity and ferric reducing antioxidant power. The complex C₁ / C₂ shows remarkable antioxidant activities as compared to the ligand L and reference compounds.     

Pomegranate (Punica granatum) juices: chemical composition, micronutrient cations, and antioxidant capacity

Abstract: Phenolics, flavonoids, anthocyanins, and tannins of pomegranate juices, obtained from 9 Tunisian ecotypes were quantified. Phenolics and flavonoids in the variety Tounsi (TN) (3299 mg gallic acid equivalents [GAE]/L and 636 mg quercetin equivalents [QE]/L of juice, respectively) were higher than in the variety Gabsi (GB) (1570 mg GAE/L and 135 mg QE/L of juice, respectively). The highest anthocyanins quantity was found in GB 2 with 156 mg cyanidin‐3‐glucoside equivalents (CGE)/L. TN 3 ecotype showed the highest tannins quantity with 2550 mg catechin equivalents (CE)/L of juice. TN 1 presented the highest radical‐scavenging activity (2, 2′‐azinobis‐3‐ethylbenzothiazoline‐6‐sulphonate [ABTS], IC₅₀ [50% inhibition concentration] = 525 mg/L), as well as the highest concentration of micronutrient cations (potassium and sodium). A high correlation (R²= 0.80) between antioxidant capacity and proanthocyanin contents was found, this suggests that proanthocyanins are the principal contributor in the antioxidant capacity of pomegranate. Our data suggest also that the high concentrations of K⁺ and Na⁺ may play a role in the adaptation of pomegranate to arid environments.     

Project scheduling under uncertainty using fuzzy modelling and solving techniques

In the real world, projects are subject to numerous uncertainties at different levels of planning. Fuzzy project scheduling is one of the approaches that deal with uncertainties in project scheduling problem. In this paper, we provide a new technique that keeps uncertainty at all steps of the modelling and solving procedure by considering a fuzzy modelling of the workload inspired from the fuzzy/possibilistic approach. Based on this modelling, two project scheduling techniques, Resource Constrained Scheduling and Resource Leveling, are considered and generalized to handle fuzzy parameters. We refer to these problems as the Fuzzy Resource Constrained Project Scheduling Problem (FRCPSP) and the Fuzzy Resource Leveling Problem (FRLP). A Greedy Algorithm and a Genetic Algorithm are provided to solve FRCPSP and FRLP respectively, and are applied to civil helicopter maintenance within the framework of a French industrial project called Helimaintenance.     

A Beta basis function neural network in CMOS subthreshold mode

Beta basis function neural networks (BBFNNs) are powerful systems for learning and universal approximation. In this paper, we present a hardware implementation of the Beta neuron using the CMOS subthreshold mode. We describe the low power–low voltage analogue Beta neuron circuit. Three main modules are used to realize the electronic Beta function: a logarithmic currentto-voltage converter, a multiplier and an exponential voltage-to-current converter. Simulation results show the validity of our neural hardware implementation. The parameters of the electronic Beta function are controlled independently by current sources. This analogue implementation could be used easily to realize analogue BBFNNs.     

Convection behavior analysis of CMOS MEMS thermal accelerometers using FEM and Hardee’s model

This paper presents convection behavior investigation of CMOS MEMS convective accelerometers using both analytical and FEM techniques. In a first part, a newly developed accelerometer 3D model is used in FEM simulations to model convection behavior as a function of design geometry and temperature. Using various sizes of two different cover shapes, sensitivity reading and its maximum position in cavity are found to be largely affected by both cover size and shape. In addition, a sensor with cavity width of 600 μm produces sensitivity saturation starting at a cavity depth of 200 μm, for both cover shapes. Using FEM data and curve fitting, differential temperature is claimed to be linearly linked to the effective heater temperature to the power of 1.7. Using the same cavity design and from computed heating efficiency values, we found that a 60 μm width heater offers the best efficiency. This cavity and heater designs give an optimal detector position of 120 μm from heater center along the sensitive axis. Moreover, dual axis accelerometers are found to be more power efficient than single axis ones. In the second part, we present Hardee’s spherical model and investigate its possible application on convective accelerometers. It is shown that inner and outer isotherms deformation, caused by accelerometer design and convection process, should be modeled by including sensor geometry parameters in the derived governing equations. Moreover, Hardee’s biasing temperature relation has to be revised if it is to be used for convective accelerometers.     

Evaluation of fibre optic sensors for structural condition monitoring

This paper presents fibre optic sensing technology for strain monitoring of engineering materials and structures. The research program consisted of laboratory tests including thermal tests, tensile tests and flexural tests, and a field application on a concrete bridge deck (Joffre Bridge) reinforced partly with fiber reinforced polymers (FRP). Four types of Fabry-Perot fibre optic sensors were investigated and compared to other types of strain gauges including Bragg fibre optic sensors and resistance strain gauges. Typical field monitoring results from the static and dynamic tests using calibrated-truck loads on the Joffre Bridge are also presented in this paper. Experimental and field monitoring results show that Fabry-Perot fibre optic sensors perform linearly and show good response to thermal variations and mechanical loading conditions. The fibre optic sensing technology shows an enhanced accuracy and has potential for significant improvement in the long-term monitoring of strain levels in field applications over conventional strain gauges. It is a promising technique for long-term ‘health’ monitoring of new and rehabilitated structures.