Electrochemical inactivation of triclosan with boron doped diamond film electrodes

This research investigated an electrochemical method for inactivating contaminated stockpiles of the biocidal agent, triclosan. The goal of the electrolysis was to produce products that were amenable to treatment in conventional activated sludge treatment systems. Triclosan oxidation in electrochemical cells with boron doped diamond (BDD) film anodes was investigated in aqueous solutions at a pH value of 12. Chronoamperometry experiments showed that direct oxidation of triclosan occurred at potentials below those for H2O, Cl-, or OH- oxidation. Measurable rates of triclosan oxidation began at potentials above 0.4 V with respect to the standard hydrogen electrode (SHE), while potentials of 0.5, 1.3, and 1.8 V were required to obtain measurable oxidation rates of H2O, Cl-, and OH-, respectively. At anode potentials below 2 V, the dominant electrode reaction involved direct triclosan oxidation, while indirect oxidation was the dominant pathway at higher potentials. However, cyclic voltammetry experiments showed that direct oxidation of triclosan resulted in the formation of a passivating film on the electrode that could only be removed by oxidation at potentials above 3 V. Direct triclosan oxidation showed a very weak potential dependence, suggesting that its oxidation was limited by chemical dependent factors rather than by an outer-sphere electron transfer reaction. Organic triclosan oxidation products consisted primarily of chlorinated acetic acids and chlorinated phenolic compounds. Although the byproducts of triclosan oxidation became increasingly less reactive with increasing electrolysis time, triclosan could be completely oxidized to CO2 at current densities above 2 mA/cm2. Microtox testing indicated that residual triclosan accounted for nearly all the toxicity in the treated water, despite the fact that chlorinated byproduct concentrations were significantly higher than those of triclosan itself.     

A longitudinal test of the investment model: The impact on job satisfaction, job commitment, and turnover of variations in rewards, costs, alternatives, and investments.

A 12-mo longitudinal study of 88 newly hired nurses and junior accountants (mean age of all Ss 24 yrs) tested a series of assumptions from the authors' (see record 1981-31481-001) investment model concerning the determinants of job satisfaction, job commitment, and turnover. In general, greater job satisfaction resulted from high job rewards and low job costs; whereas strong job commitment was produced by high rewards, low costs, poor alternative quality, and large investment size. Whereas the impact of job rewards on satisfaction and commitment remained relatively constant, job costs seemed to exert an increasingly powerful influence over time. Investment size also exerted greater impact on job commitment with the passage of time. Just prior to their leaving, the job commitment of Ss who left was best predicted by a combination of rewards, costs, and alternatives. Ss who stayed and those who left differed from one another with regard to changes over time in each investment model factor—those who left experienced greater decline in rewards, increase in costs, increase in alternative quality, and decrease in investment size than those who stayed. Turnover appeared to be mediated by a decline over time in degree of job commitment. (28 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Secondary structure of bovine alphaS2-casein: theoretical and experimental approaches

Circular dichroism and Fourier transform infrared spectroscopy of bovine alphaS2-casein both report a 24 to 32% content of alpha-helix. A consensus of sequence based predictions for alpha-helix suggests a Lys77-Gln91 helix within the sequence (Ser61-Arg125). This motif is repeated at (Ser143-Leu207), and this region contains a longer Thr145-Leu177 predicted alpha-helix. A short, seven-member alpha-helix may also organize the N-terminal peptide that precedes the first phosphoserine [-Srp-]3 cluster. As was found for other caseins studied by these spectroscopic methods, a high degree of extended beta-sheet (approximately 30%) and turns (25 to 30%) are predicted for alphaS2-casein.     

An exploration of a quasi-stable online network: A longitudinal perspective

This study uses social capital theory and social network analysis to explore how relations in an online academic communication network impact the overall structure of that network. Social network analysis is a particularly advantageous methodological tool for linking changes in microlevel choices to macrolevel structural alterations. Results indicate the online communication network’s structure exists independent of changes in communication ties. Specifically degree centrality, betweenness centrality, and clique formation indicated communication ties are initiated and discontinued over a 7-month timeframe. However, the dynamic nature of the microlevel communication choices does not mirror the quasi-stable structure of the online network. Results provide avenues for future research.     

Progressive systemic sclerosis: intrathecal pain management

PURPOSE: To determine if lucanthone crossed the blood-brain barrier in experimental animals; and to determine accelerated tumor regression of human brain metastases treated jointly with lucanthone and whole brain radiation. METHODS AND MATERIALS: The organ distribution of 3H lucanthone in mice and 125I lucanthone in rats was determined to learn if lucanthone crossed the blood-brain barrier. Size determinations were made of patients' brain metastases from magnetic resonance images or by computed tomography before and after treatment with 30 Gy whole brain radiation alone or with lucanthone. RESULTS: The time course of lucanthone's distribution in brain was identical to that in muscle and heart after intraperitoneal or intravenous administration in experimental animals. Lucanthone, therefore, readily crossed the blood-brain barrier in experimental animals. CONCLUSION: Compared with radiation alone, the tumor regression in patients with brain metastases treated with lucanthone and radiation was accelerated, approaching significance using a permutation test at p = 0.0536.     

Radioimmunoassay for measurement of bovine alpha-lactalbumin in serum, milk and tissue culture media

A sensitive, specific radioimmunoassay for bovine alpha-lactalbumin (alpha-la) suitable for measurement of serum, tissue culture media and milk was developed. alpha-La was not detected in serum from prepubertal male or female cattle, but was detected as early as 60 d of gestation in nulliparous Holstein heifers, the level being greatly increased during the last one third of gestation. Serum from cross bred beef heifers contained less alpha-la and it was not detected until late gestation. Concentrations of alpha-la in serum samples from pregnant multiparous Holstein cows decreased at drying-off and subsequently increased just before parturition. Secretion of alpha-la by mammary tissue explants from steroid-primed prepubertal Holstein heifers was induced by the addition of bovine prolactin, ovine prolactin or human growth hormone to tissue culture media.     

Metaphor and psychology: A reply to Gholson and Barker.

Suggests, in reply to the analysis of B. Gholson and P. Barker (see PA, 73:10704), that they may have overlooked a single construct (the underlying metaphor of the psyche) that embodies incommensurable, although not necessarily competing, theories that may distinguish evolution in psychology from that of other sciences. It is contended that while technology, methodology, novelty, and empirical results are factors in the evolution of psychology, the evolution can be measured by changes in metaphor. (6 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

2008半导体库存仍然居高不下

据iSuppli公司报告,2008年第一季度多数厂商在季中降低或者缩窄了营业收入预期,与当时相比,第二财季的情况比较正面.在第二财季季中展望中,多数厂商重申了季度营业收入预期或者只是略微收紧了预估区间.     

Impact of computers on professional practice: A survey of current practices and attitudes.

Surveyed 227 practicing psychologists to explore the impact of computers on the everyday practice of psychology and practitioners' attitudes toward specific uses of computers. Whereas more than half of the respondents reported using computers in their practices, most restricted their use to clerical applications. Few practitioners used their computer for more clinical applications. Reasons most frequently reported for not using computers related to lacking the necessary skills and experience and to financial considerations. Overall, practitioners had positive attitudes toward a variety of specific applications of computers. Implications of these findings for facilitating the appropriate use of computers by practitioners are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)