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排序方式: 共有1666条查询结果,搜索用时 31 毫秒
91.
92.
Chromatographic separations are an expanding technology for the separation of high value products, particularly in the area of pharmaceutics, food, and fine chemicals. The simulated moving bed (SMB) process as a continuous chromatographic separation process is an interesting alternative to conventional batch chromatography, and gained more and more impact recently. The SMB process is realized by connecting several single chromatographic columns in series. A countercurrent movement of the bed is approximated by a cyclic switching of the inlet and outlet ports in the direction of the fluid stream. Because of its complex dynamics, the optimal operation and automatic control of SMB processes is a challenging task. This paper presents the design of a model-based optimization and control scheme for SMB chromatographic separation processes and its application to the separation of fructose and glucose. We propose a two-layer control architecture where the optimal operating trajectory is calculated off-line by dynamic optimization based on a rigorous process model. The parameters of the model are adapted based on online measurements. The low-level control task is to keep the process on the optimal trajectory despite disturbances and plant/model mismatch. Here identification models based on simulation data of the rigorous process model along the optimal trajectory are combined with a suitable local controller. The efficiency of the trajectory control algorithm is shown in a simulation study for the separation of fructose and glucose on an 8-column SMB plant. 相似文献
93.
We describe a patient with sporadic dystrophic epidermolysis bullosa associated with well-documented atopic dermatitis. We discuss this case in relation to a newly described clinical subtype of epidermolysis bullosa known as epidermolysis bullosa pruriginosa, a dystrophic variant associated with prominent pruritus. The relations of this case of sporadic dystrophic epidermolysis bullosa with other dominantly inherited forms of dystrophic epidermolysis bullosa such as the Pasini variant, the pretibial variant, and Bart's syndrome are also discussed. The role of atopic dermatitis in exacerbating dystrophic epidermolysis bullosa in this patient raises an important consideration in the care of this group of patients. 相似文献
94.
FD Knollmann R Sorge A Mühler J M?urer P Muschick JC B?ck R Felix 《Canadian Metallurgical Quarterly》1997,32(12):755-762
RATIONALE AND OBJECTIVES: Intravascular contrast agents for magnetic resonance imaging (MRI) facilitate the quantification of tissue perfusion. The authors determined the hemodynamic tolerance of these agents. METHODS: Doses of 0.05, 0.15, and 0.45 mmol/kg of the polymeric intravascular contrast agent gadolinium-DTPA-polylysine, and di-nitrobenzyl-gadolinium-DTPA, a non-polymeric intravascular contrast agent with high protein binding, and gadolinium-DTPA dimeglumine, a paramagnetic contrast agent with extracellular distribution, were injected into 18 normal male rats as a peripheral intravenous bolus. Systolic, diastolic, and mean blood pressure, left ventricular end-diastolic and developed pressure, positive rate of pressure change (+dP/dt), dP/dt, the rate-pressure product, and heart rate were recorded during a period of 20 minutes. Hemodynamic effects were established by analysis of variance for repeated measurements. RESULTS: There was a transient increase of all blood pressure parameters and contractility for Gd-DTPA-polylysine at the dose of 0.45 mmol/kg only. Di-nitrobenzyl-Gd-DTPA increased blood pressure parameters at 0.45 mmol/kg only. At doses of 0.05 and 0.15 mmol/kg, no significant hemodynamic effects were observed. CONCLUSIONS: The authors conclude that Gd-DTPA-polylysine is hemodynamically safe at doses to 0.15 mmol/kg and acts like a plasma expander at higher doses after peripheral bolus injection in normal rats. Additional investigations are indicated to elucidate the mechanism of a nonsignificant and satiable transient hemodynamic depression after injection of 0.05 mmol/kg DNB-Gd-DTPA. 相似文献
95.
A simple electronic measuring cup for the blind is described. It uses an array of infrared level detectors, which are immersed in the medium to be measured. When used with a standard 1-liter glass, the filling level is indicated acoustically in increments of 50 ml. 相似文献
96.
Friedl-Vallon F Maucher G Seefeldner M Trieschmann O Kleinert A Lengel A Keim C Oelhaf H Fischer H 《Applied optics》2004,43(16):3335-3355
MIPAS-B2 is a balloon-borne limb-emission sounder for atmospheric research. The heart of the instrument is a Fourier spectrometer that covers the mid-infrared spectral range (4-14 microns) and operates at cryogenic temperatures. Essential for this application is the sophisticated line-of-sight stabilization system, which is based on an inertial navigation system and is supplemented with an additional star reference system. The major scientific benefit of the instrument is the simultaneous detection of complete trace gas families in the stratosphere without restrictions concerning the time of day and viewing directions. The specifications, the design considerations, the actual realization of the instrument, and the results of characterization measurements that have been performed are described. 相似文献
97.
Erdmann N Betti M Kollmer F Benninghoven A Grüning C Philipsen V Lievens P Silverans RE Vandeweert E 《Analytical chemistry》2003,75(13):3175-3181
The resonance and nonresonant laser ionization of uranium atoms sputtered from thin metal films and individual micrometer-size uranium oxide particles, respectively, was studied to evaluate a new setup for the analysis of actinide-containing micrometer-size particles. Experiments using nonresonant (193-nm) ionization of atoms and molecules sputtered from micrometer-size uranium oxide particles have shown that the uranium detection efficiencies for sputtered neutral atoms are approximately 2 orders of magnitude higher than for secondary ions. In uranium particles of 0.5-microm diameter, 6 x 10(6) atoms of 235U were easily detected and the isotopic ratio of 235U/238U = 0.0048 +/- 4.6% is in excellent agreement with the certified value. The use of two-color, two-step resonance ionization of the sputtered neutral uranium atoms from thin films was investigated. Several excitation schemes were tested, and a significant population of several low-lying metastable states after ion sputtering was observed. Autoionizing states for double-resonant ionization were determined, and the high selectivity of ionization schemes involving these autoionizing states was illustrated by comparing the flight-time distributions of different sputtered species obtained both by resonance and nonresonant multiphoton (355-nm) laser postionization. Ideally, the options for resonance as well as nonresonant ionization would be combined in a single setup, to obtain a large gain in sensitivity and selectivity. Thus, information about the main components as well as specific isotopic information of a trace element could be obtained from the same single particle. 相似文献
98.
Certon D Felix N Lacaze E Teston F Patat F 《IEEE transactions on ultrasonics, ferroelectrics, and frequency control》2001,48(1):85-92
Plate waves inside the piezoelectric layer are much involved in the element cross-coupling in transducer arrays for medical imaging. In this work, such waves are analyzed in 1-3 piezocomposite materials on the basis of conventional guided modes formalism in which the piezocomposite is considered as a homogeneous medium. Cross-coupling measurements have been made on two different transducer arrays using a network analyzer and a laser interferometric probe. It is shown how the analysis in terms of symmetrical Lamb waves gives an interesting qualitative interpretation, explaining most of the cross-coupling amplitude variations with frequency. Results show that the 0th and 3rd symmetrical Lamb waves are mainly involved in coupling inside composite plates. The S0 mode is responsible for the inter-element coupling, whereas the S3 mode widens the effective width of the excited element 相似文献
99.
Felix CL Bewley WW Vurgaftman I Bartolo RE Stokes DW Meyer JR Yang MJ Lee H Menna RJ Martinelli RU Garbuzov DZ Connolly JC Maiorov M Sugg AR Olsen GH 《Applied optics》2001,40(6):806-811
We review the recent progress of electrically injected and optically pumped mid-IR lasers based on antimonide quantum wells with the type II W configuration. W quantum-well diodes have achieved cw operation up to 195 K at lambda = 3.25 mum. Optically pumped devices that employ the diamond pressure bond heat sink have reached 290 K at 3 mum and 210 K at 6 mum. Pulsed power conversion efficiencies of up to 7% at 220 K have been attained by use of an optical pumping injection cavity approach, in which an etalon cavity for the pump beam significantly enhances its absorptance. The angled-grating distributed-feedback configuration has been used to obtain near-diffraction-limited output for an optical pumping stripe width of 50 mum. 相似文献
100.
Flexibility performance: Taguchi's method study of physical system and operating control parameters of FMS 总被引:2,自引:0,他引:2
In present manufacturing environment, the manufacturing flexibility has become one of the strategic competitive tools. Flexibility refers to the availability of alternative resources. These resources may have varied parameters, particularly related to physical and operating system. These physical and operating parameters of alternative resources may influence the system's performance with the changing levels of flexibility and operational control parameters such as scheduling rules. Is increase in a flexibility level provides desired improved performance output? If yes, than under what conditions of physical and operating parameters and under which control strategy (CS)? Is improved performance is present at all increasing levels of flexibility? Flexible manufacturing system (FMS) being consist of numerous physical and operating parameters and complex in nature, the solution to these questions can provide an understanding of the productive levels of flexibility for a given physical and operating parameters of an FMS. This paper establishes the need of modelling of the physical and operating parameters of flexible manufacturing system along with flexibility and presents a simulation study under Taguchi's method analysis of these parameters. The paper contributes an approach to study the impact of variations in physical and operating parameters of an FMS and to identify the level of these variations that do not restrict the advantages of flexibility. The results show that the expected benefits from increasing the levels of flexibility and a superior CS may not be achieved if the physical and operating parameters of alternative machines have variations. Taguchi's method analysis indicates that relative percentage contribution of variations in physical and operating parameters of alternative resources should be negligible or minimum in the performance of FMS. Their increasing relative contribution may restrict the advantages of flexibility. If these variations are higher than increase in flexibility level may be counter productive. 相似文献