Dehydration anorexia in decerebrate rats.

Hypertonic saline (HS) administered intraperitoneal/ly (ip) reduced the intake of sucrose solution infused intraorally in tube-fed decerebrate rats, as it did in control animals. Similarly, either ip or intravenous HS markedly decreased the intake of laboratory chow by neurologically intact control rats. These observations complement recent findings that lesions of putative osmoreceptors in the ventral diencephalon, which eliminate thirst and blunt pituitary secretion of vasopressin and oxytocin in response to HS in rats, have no apparent effect on the HS-induced inhibition of food intake. Taken together they support previous studies indicating an important role for the caudal brainstem in the central control of food intake and suggest that such brainstem control may also include the inhibition of food intake induced by acute hyperosmolality. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Experimental measure of dynamic spatial-hole burning in DFB lasers

Spatially resolved measurements of carrier density in two 1.3-μm distributed feedback laser diodes are reported. By measuring the response of the spontaneous emission intensity to a 50-MHz drive current, small relative changes in the carrier density can be observed. When biased below threshold, the carrier density fluctuates uniformly in the laser cavity with a phase delay corresponding to the carrier lifetime. When biased above threshold, the carrier density response shows clear evidence of spatial hole burning. The location of the minimum and the net change in carrier density, however, depend on the particular laser     

Adaptive Filter Processing in Microwave Remote Heart Monitors

This commmunication describes some current applications tions of adaptive filtering to the processing of microwave Doppler signals for heart rate monitoring. The problem has been approached in the past using signal processing techniques such as peak detection or autocorrelation. These methods either require large amounts of data or tend to be unreliable. This communication utilizes some recent techniques used in speech processing and applies them to heartbeat detection, thus allowing on-line processing of sampled microwave heart signals. The presentation includes a model for the signal, brief discussions of the algorithms evaluated, and qualitative analysis of performance compared to EKG measurements.     

A decision support system for telecommunications

We have built a Decision Support System (DSS) which can to aid strategic management within the industry in making vital decisions in relation to Customer and Network profiles. This enables managers in the respective areas within the industry to fully utilise the vast amounts of data available to make projections and decisions in relation to utilisation of valuable resources. Copyright © 2002 John Wiley & Sons, Ltd.     

Quantitative Determination of Cellular Farnesyltransferase Activity: Towards Defining the Minimum Substrate Reactivity for Biologically Relevant Protein Farnesylation

Prenylation is a post‐translational modification wherein an isoprenoid group is attached to a protein substrate by a protein prenyltransferase. Hundreds of peptide sequences are in vitro substrates for protein farnesyltransferase (FTase), but it remains unknown which of these sequences can successfully compete for in vivo prenylation. Translating in vitro studies to predict in vivo protein farnesylation requires determining the minimum reactivity needed for modification by FTase within the cell. Towards this goal, we developed a reporter protein series spanning several orders of magnitude in FTase reactivity as a calibrated sensor for endogenous FTase activity. Our approach provides a minimally invasive method to monitor changes in cellular FTase activity in response to environmental or genetic factors. Determining the reactivity “threshold” for in vivo prenylation will help define the prenylated proteome and identify prenylation‐dependent pathways for therapeutic targeting.     

Protective Performance of Environmentally Stressed Fabrics Containing Melamine Fiber Blends

In this study, the mechanical properties critical to the protective performance of firefighter turnout gear were evaluated for environmentally stressed outer shell (OS) fabrics containing melamine fiber blends. Environmental stress factors that affect the durability of turnout gear include temperature, ultraviolet (UV) radiation, moisture, abrasion, and laundering. The effect of fiber blend, fabric construction, and finishing processes including water repellent coatings and pigmented melamine-containing OS fabrics were also studied. Melamine-containing OS fabrics show comparable thermal protective performance and have superior tear resistance when compared to the traditionally used polyaramid blends. This study reveals that the thermal protective protection (TPP) rating of fabric assemblies incorporating environmentally stressed OS fabrics containing melamine fiber blends is well above the NFPA minimum TPP requirement of 35 cal/cm². However, the tear strength (measured using ASTM D 5587 standard test method) of all melamine-containing OS fabrics exposed to environmental stresses was observed to have significantly deteriorated, and most OS fabrics, depending on fiber blend and fabric structure, would fail to meet requirements of NFPA 1971 standard. The study thus suggests that environmental stressing has a more detrimental impact on the tear strength than the thermal protective performance of OS fabrics. Deterioration in tear strength of all UV exposed OS fabrics is largely due to photodegradation of constituent fibers. Changes in tear strength of OS fabrics subjected to thermal exposures and laundering is cumulative effect of loss in tensile strength of single yarns and dimensional stability of the fabric itself. Furthermore, finishing treatments affect performance properties of fabric by increasing fiber packing factor in yarn, changing yarn crimp and yarn spacing thereby making dimensional changes to the fabric. Surface coatings alter tear resistance of fabric by influencing yarn slippage and fabric rigidity. Fabrics dyed with black and dark blue dyes cause less UV degradation of fibers than bright yellow and brown dyes.     

Microwave-assisted rapid discharge sintering of a bioactive glass�Cceramic

Bioactive glass-ceramics have been developed as successful bone graft materials. Although conventional sintering in an electrically-heated furnace is most commonly used, an alternative microwave plasma batch processing technique, known as rapid discharge sintering (RDS), is examined to crystallise the metastable base glass to form one or more ceramic phases. Apatite-mullite glass-ceramics (AMGC) were examined to elucidate the effects of RDS on the crystallization of a bioactive glass-ceramic. By increasing the fluorine content of the glass, the fluorapatite (FAp) and mullite crystallization onset temperatures can be reduced. Samples were sintered in a hydrogen and hydrogen/nitrogen discharge at temperatures of ≈800 and 1000 °C respectively with the higher sintering temperature required to form mullite. Results show that the material can be densified and crystallised using RDS in a considerably shorter time than conventional sintering due to heating and cooling rates of ≈400 °C/min.     

Deregulated power prices: changes over time

We examine price by season and by year in 14 deregulated markets, by looking at diurnal price patterns and price volatility. Power price volatility is measured by price velocity, the daily average of the absolute value of price change per hour, which is broken into a component expected from the average diurnal pattern, and an unexpected component. Deregulated markets can be categorized into three groups: stable markets, markets that experienced one bad period or season of high price excursion, and chaotic markets. Britain, Spain and Scandinavia show consistent price patterns and low unexpected price velocity; a thoughtful consumer could reasonably implement demand side management (DSM) by shaping consumption patterns to reflect price. California, New Zealand and Alberta are examples of markets that had a period of very high price excursion; we discuss factors affecting public reaction to this. Australian power markets have inconsistent price patterns from season to season and year to year, and very high unexpected price velocity. Planned DSM in these markets would be very difficult. We offer four policy considerations for markets considering deregulation in the future.