Controlled-Release Matrix of Acetaminophen-Ethylcellulose Solid Dispersion

In this study ethylcellulose was evaluated as a carrier for preparation of prolonged release acetaminophen tablets. Solid dispersions containing three levels of ethylcellulose and acetaminophen (1:3; 1:1; 3:1) were prepared by the solvent method. Also physical mixtures at the same level of ethylcellulose and acetaminophen were prepared. Systems composed of solid dispersion or physical mixture containing the equivalent weight of 50 mg acetaminophen, Lactose fast-flo as diluent and 1% magnesium stearate as lubricant were compressed into tablets and tested for dissolution. The dissolution data showed that the drug release decreased as the level of ethylcellulose increased in the solid dispersion formulations. The drug release from tablets prepared with solid dispersion followed the diffusion controlled model for inert porous matrix, while the drug release from tablets prepared with physical mixture followed the first-order kinetic model.     

Two studies of the long-term follow-up of minimal therapist contact treatments of vascular and tension headache.

Tension and vascular headache patients, initially treated with biofeedback and/or relaxation training in either a minimal therapist contact protocol (3 visits) or an intensive individual protocol (10 or 16 visits) were followed-up prospectively for 2 years. In the first study, for the first 6 months of follow-up, half of all patients continued to keep headache diaries and were seen monthly and the other half had only minimal contact. The results at 1-year follow-up, based on 4 weeks of daily headache diaries, revealed equally good maintenance from both treatment protocols and from both follow-up conditions. In Study 2, we found that patients remained improved over pretreatment baseline levels at the 2-year follow-up regardless of initial treatment intensity. Approximately three quarters of vascular patients who were initially improved at posttreatment remained improved at 2 years. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Converting interpreters into compilers

There is an effective and quite general method of manually deriving compilers from programming-language interpreters without dealing directly with machine language. The method is an implementation of the largely theoretical and under-appreciated concept of partial computation, but can be understood on its own terms. It involves the translation of a source program's intermediate form into the interpreter's implementation language. This paper shows how the method can be used to transform both a sample iterative interpreter and a sample recursive interpreter into compilers. The result can be a large gain in program execution speed. Other advantages of the method, including the ease and practicality of applying it, are discussed.     

Optically generated electrical-modulation formats in digital-microwave link applications

We investigate a novel technique to generate the transmission signal in digital-microwave link applications. This technique is based on a photonic device that achieves both electrical modulation (QAM, PSK, ASK) and harmonic upconversion of the microwave carrier. Simulation results are provided for a seventh-harmonic 38.5-GHz transmission of a 2.5-Gbps signal through a 1-km fiber span. The impact of fiber chromatic-dispersion on the link bandwidth is also analyzed.     

Longitudinal relations between forgiveness and conflict resolution in marriage.

Does forgiveness predict later conflict resolution in married couples? Twelve-month follow-up data on conflict resolution were collected from the couples studied by F. D. Fincham, S. R. Beach, and J. Davila (see record 2004-11293-007), who had provided earlier reports of forgiveness and conflict resolution. For wives, the positive dimension of forgiveness or benevolence predicted husbands' later reports of better conflict resolution controlling for initial levels of conflict resolution. This finding was independent of wives' marital satisfaction and the degree of hurt engendered by husbands' transgressions. For husbands, the only predictor of wives' reports of later conflict resolution was initial level of conflict resolution. The findings are discussed in terms of the direction of effect between forgiveness and conflict resolution and of the mechanisms that might link them. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A Class of Algorithms for Collision Resolution with Multiplicity Estimation

The wireless connectivity in pervasive computing has ephemeral character and can be used for creating ad hoc networks, sensor networks, connection with RFID (Radio Frequency Identification) tags etc. The communication tasks in such wireless networks often involve an inquiry over a shared channel, which can be invoked for: discovery of neighboring devices in ad hoc networks, counting the number of RFID tags that have a certain property, estimating the mean value contained in a group of sensors etc. Such an inquiry solicits replies from possibly large number of terminals n. This necessitates the usage of algorithms for resolving batch collisions (conflicts) with unknown conflict multiplicity n. In this paper we present a novel approach to the problem of collision resolution for batch conflicts. We show how the conventional tree algorithms for collision resolution can be used to obtain progressively accurate estimation of the multiplicity. We use the estimation to propose a more efficient binary tree algorithm, termed Estimating Binary Tree (EBT) algorithm. The EBT algorithm is suited for implementation when the conflicting nodes are passive, such as e.g. RFID tags. We extend the approach to design the Interval Estimation Conflict Resolution (IECR) algorithm. For n→∞ we prove that the efficiency achieved by IECR for batch arrivals is identical with the efficiency that Gallager’s FCFS algorithm achieves for Poisson packet arrivals. For finite n, the simulation results show that IECR is, to the best of our knowledge, the most efficient batch resolution algorithm reported to date.     

Frames of Reference in Mobile Augmented Reality Displays.

In 3 experiments, the authors investigated spatial updating in augmented reality environments. Participants learned locations of virtual objects on the physical floor. They were turned to appropriate facing directions while blindfolded before making pointing judgments (e.g., "Imagine you are facing X. Point to Y"). Experiments manipulated the angular difference between the learning heading and the imagined heading and between the actual heading and the imagined heading. The effect of actual-imagined on pointing latency was observed for naive users but not for users with brief training or instructions concerning the fact that objects can move with body movements. The results indicated that naive users used an environment-stabilized reference frame to access information arrays, but with experience and instruction the nature of the representation changed from an environment stabilized to a body stabilized reference frame. (PsycINFO Database Record (c) 2010 APA, all rights reserved)