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131.
Wim Six Gert‐Jan Bex Albert Van Bael Jozefien De Keyzer Frederik Desplentere 《Polymer Engineering and Science》2019,59(7):1489-1498
Multicomponent injection molding often combines a stiff thermoplastic material with a thermoplastic elastomer or thermoplastic vulcanite. Recently, for high‐demanding applications, a novel process has been developed to replace these thermoplastic elastomers or vulcanite with a thermoset rubber, for example, NBR or EPDM. One of the most important properties of a two component product is an adequate adhesion between both components. This paper describes a method, which combines experiments and numerical simulations to predict the adhesion strength between a thermoplastic, semicrystalline HDPE, and an EPDM thermoset rubber. This method uses numerical simulations of the interfacial temperature and the local degree of cure. The local interface temperature is combined with the results of DSC measurements to predict the degree of melting, subsequently linked to the ability to develop adhesive strength. The degree of cure is used to determine the local rubber strength. The combination of the given data will be used to predict interfacial strength. The results obtained by proposed numerical strategy have been successfully validated with experimental data on a simple plate product. POLYM. ENG. SCI., 59:1489–1498 2019. © 2019 Society of Plastics Engineers 相似文献
132.
Frederik Wolf Lena Hecht Heike P. Schuchmann Edme H. Hardy Gisela Guthausen 《European Journal of Lipid Science and Technology》2009,111(7):730-742
Multiple emulsions of W1/O/W2 type are of major interest in life sciences, offering possibilities for the encapsulation of water‐soluble active agents. In food science, they are also applied for fat reduction. The droplet size distributions of the inner and outer emulsions are of main importance as they influence the rheological and sensorial properties, the release kinetics, as well as the structural and microbial stability. However, the determination of the inner and outer droplet size distributions is a major challenge, as conventional measurement techniques cannot be applied. Pulsed‐field gradient nuclear magnetic resonance (PFG‐NMR) is well known as a non‐destructive tool for droplet size determination, especially in simple emulsions. In this work, double emulsions of the W1/O/W2 type were prepared with polyglycerol‐polyricinoleate (PGPR) and polyoxyethylen‐20‐sorbitan monolaurate (Tween 20) as emulsifiers by means of rotor‐stator emulsification machines. PFG‐NMR was applied for measurements of the inner phase (W1) droplet size distribution as well as for the characterization of the O phase. The W1 values were compared with results from laser light diffraction of simple emulsions (W1/O type) and were found to be consistent within the experimental errors, if restricted diffusion in the outer water phase (W2) and additional effects are considered. 相似文献
133.
Aneliya Knauthe Sonnhild Mittag Laura Bloch Kai Frederik Albring Martin Schmidt Oliver Werz Otmar Huber 《International journal of molecular sciences》2022,23(6)
The therapeutic activities of natural plant extracts have been well known for centuries. Many of them, in addition to antiviral and antibiotic effects, turned out to have anti-tumor activities by targeting different signaling pathways. The canonical Wnt pathway represents a major tumorigenic pathway deregulated in numerous tumor entities, including colon cancer. Here, we investigated the acylphloroglucinols hyperforin (HF) from St. John’s wort (Hypericum perforatum L.) and myrtucommulone A (MC A) from myrtle (Myrtus communis) and semi-synthetic derivatives thereof (HM 177, HM 297, HM298) for their effects on Wnt/β-catenin signaling. None of these substances revealed major cytotoxicity on STF293 embryonic kidney and HCT116 colon carcinoma cells at concentrations up to 10 μM. At this concentration, HF and HM 177 showed the strongest effect on cell proliferation, whereas MC A and HM 177 most prominently inhibited anchorage-independent growth of HCT116 cells. Western blot analyses of active β-catenin and β-catenin/TCF reporter gene assays in STF293 cells revealed inhibitory activities of HF, MC A and HM 177. In line with this, the expression of endogenous Wnt target genes, Axin and Sp5, in HCT116 cells was significantly reduced. Our data suggest that the acylphloroglucinols hyperforin, myrtucommulone A and its derivative HM 177 represent potential new therapeutic agents to inhibit Wnt/β-catenin signaling in colon cancer. 相似文献
134.
Frederik Dostal 《电子与电脑》2008,(1):68-71
概述 大部份电源管理电路的稳压特性都是由转换器环路传递函数来定义,这个函数可以用波德图(Bode Plot)绘制出来.这种图表可以表达出环路增益和环路相位位移在不同频率下的特性,提供有关控制环路的速度和电源稳定性的重要信息.无疑,绘制波德图最理想的是用网络分析仪,但也可用实验室内一些比较简单的工具来绘制. 相似文献
135.
Grewe Oliver; Nagel Frederik; Kopiez Reinhard; Altenmüller Eckart 《Canadian Metallurgical Quarterly》2007,7(4):774
Most people are able to identify basic emotions expressed in music and experience affective reactions to music. But does music generally induce emotion? Does it elicit subjective feelings, physiological arousal, and motor reactions reliably in different individuals? In this interdisciplinary study, measurement of skin conductance, facial muscle activity, and self-monitoring were synchronized with musical stimuli. A group of 38 participants listened to classical, rock, and pop music and reported their feelings in a two-dimensional emotion space during listening. The first entrance of a solo voice or choir and the beginning of new sections were found to elicit interindividual changes in subjective feelings and physiological arousal. Quincy Jones' "Bossa Nova" motivated movement and laughing in more than half of the participants. Bodily reactions such as "goose bumps" and "shivers" could be stimulated by the "Tuba Mirum" from Mozart's Requiem in 7 of 38 participants. In addition, the authors repeated the experiment seven times with one participant to examine intraindividual stability of effects. This exploratory combination of approaches throws a new light on the astonishing complexity of affective music listening. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
136.
137.
Frederik Hammes Arsne Seka Kris Van Hege Tom Van de Wiele Jan Vanderdeelen Steven D Siciliano Willy Verstraete 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2003,78(6):670-677
High concentrations of soluble calcium in industrial wastewater present problems due to the calcification of downstream processing. The current trend towards circuit closure and increased water re‐use will escalate this problem. We investigated ureolytic microbial carbonate precipitation as a novel process for removing excess calcium from industrial effluents. Two laboratory‐scale reactors, both with a hydraulic retention time of 8 h, were fed with 1.8 dm3 of anaerobic effluent (about 11 mM Ca2+) from a paper recycling plant. Both reactors were inoculated with pre‐cultivated calcareous sludge and the treatment reactor was additionally dosed with urea to a final concentration of 8.3 mM . Even though the anaerobic wastewater was saturated as such with respect to CaCO3, urea addition and hydrolysis was shown to be a pre‐requisite for precipitation. Almost all (85–90% w/v) of the soluble calcium was precipitated as CaCO3 and removed through sedimentation in the treatment reactor. This bio‐catalytic process presents an uncomplicated and efficient method for the removal of calcium from industrial wastewater. Copyright © 2003 Society of Chemical Industry 相似文献
138.
Karel Verscheure Mieke Campforts Frederik Verhaeghe Eddy Boydens Bart Blanpain Patrick Wollants Maurits Van Camp 《Metallurgical and Materials Transactions B》2006,37(6):929-940
Furnace protection by water-cooled freeze linings becomes increasingly important as the metal producing industry attempts
to achieve higher process intensities. Systematic investigations of the growth and the resulting microstructure and compositional
profile of freeze linings are necessary to understand the behavior of freeze linings, their relation with the industrial process,
and their interaction with the wall cooling system. We have developed a technique based on the submergence of a water-cooled
probe into a liquid slag bath. Freeze linings of two industrial nonferrous slags have been produced using this technique and
their growth, microstructural, and compositional profiles as a function of submergence time were determined. Thermodynamic
equilibrium for the investigated slag systems was calculated and compared with the observed microstructures. The freeze linings
form in approximately 15 minutes. Close to the water cooling, the freeze linings are predominantly amorphous in structure.
With increasing distance from the water cooling, the proportion of crystalline phases increases and bath material is entrapped
in the microstructure. Cellular crystals are observed close to the bath. The freeze linings exhibit an approximate homogeneous
composition. The results demonstrate that the technique is a successful tool in obtaining information on the growth, microstructure,
and composition of freeze linings in industrial water-cooled furnaces. 相似文献
139.
Frederik M. L. L. De Belie David M. Van de Sype Koen De Gussemé Wouter R. A. Ryckaert Jan A. A. Melkebeek 《Electrical Engineering (Archiv fur Elektrotechnik)》2007,89(5):363-370
A novel digital voltage controller for boost PFC converters is proposed in this paper. If a fast voltage compensator is applied
to control the DC output voltage, the DC output voltage ripple, pulsating at twice the grid frequency, causes a third harmonic
of considerable magnitude in the line current. The new controller samples the DC-bus voltage at all zeroes of its ripple,
resulting in a fast voltage control algorithm that guarantees a low total harmonic distortion in the line current. The performance
of the proposed voltage controller is compared to other voltage controllers, by using a prototype of a digitally controlled
boost PFC convertor. 相似文献
140.
Strijkers GJ Mulder WJ van Heeswijk RB Frederik PM Bomans P Magusin PC Nicolay K 《Magma (New York, N.Y.)》2005,18(4):186-192
Paramagnetic liposomes, spherical particles formed by a lipid bilayer, are able to accommodate a high payload of Gd-containing
lipid and therefore can serve as a highly potent magnetic resonance imaging contrast agent. In this paper the relaxation properties
of paramagnetic liposomes were studied as a function of composition, temperature and magnetic field strength. The pegylated
liposomes with a diameter of approximately 100 nm were designed for favorable pharmacokinetic properties in vivo. The proton
relaxivity, i.e. the T1 relaxation rate per mmol of Gd(III) ions, of liposomes with unsaturated DOPC phospholipids was higher than those with saturated
DSPC lipids. Addition of cholesterol was essential to obtain monodisperse liposomes and led to a further, although smaller,
increase of the relaxivity. Nuclear magnetic relaxation dispersion measurements showed that the relaxivity was limited by
water exchange. These results show that these paramagnetic liposomes are very effective contrast agents, making them excellent
candidates for many applications in magnetic resonance imaging. 相似文献