Molecular aspects of the transport and toxicity of ochratoxin a

Ochratoxins are a class of naturally occurring compounds produced by several fungi. The most toxic is ochratoxin A (OTA), and occurrence of some human nephropathies and tumors correlate with enhanced OTA exposure. In this Account, the following areas are examined: molecular details of the binding of OTA to human serum albumin (HSA), the influences of binding to HSA on the trans-port of OTA across epithelial cell membranes by organic anion transport proteins, the oxidative activation of OTA, and the formation of OTA adducts with biological molecules. These studies are beginning to provide a detailed chemical model for the trans-port, accumulation, and genotoxic and carcinogenic effects of OTA.     

城市化进程中失地农民的利益保障——以经济社会学理论为分析视角

随着经济和社会的发展,我国城市化和工业化进程不断加快.在这个过程中,农村集体土地不可避免地被大量征用,导致众多文化素质不高,劳动技能单一的失地农民成为最弱势、最缺乏保障和最边缘化的群体.在经济社会学的视角下,可以从经济资本、社会资本和人力资本三个方面解析造成失地农民贫苦境地的原因,并进一步为该问题的解决提供了一个可行之道,以实现让农民公平地分享城市化发展的社会成果,保证其得到可持续生计.     

社会性别视野下的多婚女性个案探讨

对一个有三次婚姻经历的女性进行了深度访谈.针对受访者的口述,分析了女性在婚姻中的社会性别观念,认为当今社会中,以父权制意识形态为中心的价值体系仍然存在,而且影响着妇女的婚姻角色选择.     

MACD与K线图技术在证券投机中的实证研究

利用MACD趋势指标与K线形态图进行相互验证技术,改进一般的基于MACD的证券买卖准则。实证结果表明,基于改进后的MACD买卖准则进行证券投机,几乎能使投机者捕捉到每一波段行情,从而获取较高收益。     

Effects of annealing temperature on the microstructure and properties of the 25Mn-3Si-3Al TWIP steel

Microstructures and mechanical properties of the 25Mn twinning induced plasticity (TWIP) steel at different annealing temperatures were investigated. The results indicated that when the annealing temperature was 1000°C,the 25Mn steel showed ex-cellent comprehensive mechanical properties,the tensile strength was about 640 MPa,the yield strength was higher than 255 MPa,and the elongation was above 82%. The microstructure was analyzed by optical microscopy (OM),X-ray diffraction (XRD),and transmission electron...     

基于multi-agents的网络防卫体系中预警定位系统的研究与实现

传统的网络安全措施,如加密认证、防火墙和入侵检测系统等,虽然在保护信息的保密性、完整性、可用性和控制访问方面有一定的效果,但在协同和预警方面依然存在不足.文章提出了1个基于multi-agents的网络安全防卫系统,该系统由协同预警定位系统、协同审计系统、安全隔离系统、事故恢复系统等多个模块构成,模块之间由多个多级分层agents来负责通信任务.系统控制中心的agent server负责控制和协调整个安全体系,制定全网统一的安全控制策略.在该系统中,整个网络被划分成不同级别的分区,建立不同级别的协同预警定位系统,各分区既相互协作,又能够独立自治,通过协作的方式共同维护着整个网络的安全.在IPv6环境下测试的结果表明,该系统可以高效进行预警,IDS的捕获率约为95%、漏报率小于6%、误报率小于7%.     

基于三维模型的飞机红外图像仿真研究

要对红外成像制导导弹攻击飞机的过程进行仿真,需要生成目标飞机的红外图像。当飞机受到导弹攻击时会采取各种机动动作进行规避,这就使导引头所探测到的图像随着弹目距离、飞机姿态而变化,所生成的红外图像必需能够反应这种变化。文章首先根据能量守恒定律和黑体辐射定律,并综合考虑了大气透过率、光学系统透过率和探测器响应率的影响,推导了导引头探测器接收到的飞机红外辐射功率计算公式,利用该公式计算出所建飞机三维模型每个面的辐射功率,并将其转换为红外灰度值,最后利用OpenGL技术直接对飞机三维模型进行操作,以实现各种位置、姿态下三维飞机模型到二维图像的转换,并用光学系统的点扩散函数与输出的图像进行卷积,最终得到反映光学模糊的飞机红外图像,最后开发了红外图像仿真软件,利用该软件生成了几种不同位置、不同姿态下的飞机红外图像,并对其进行了分析。     

Orientation angle workspaces of planar serial three-link manipulators

This paper presents a classification on the workspaces of planar serial three-link manipulators, that is, position workspace and orientation angle workspace. Position workspace indicates the region reached by the reference point on the end-effector. Orientation angle workspace indicates a set of angle ranges by which the end-effector can reach with certain orientation for every point in the reachable position workspace. By introducing a virtual equivalent mechanism, reachable position workspace can be divided into several Grashof intervals and non-Grashof intervals. The calculation equations of orientation angle workspace are deduced in three situations according to the relationships among four link lengths in the virtual four-bar chain. Three examples are given for three kinds of relationship of link lengths. The orientation angle workspace of extended groups, that is, two of the three link lengths equal, and the orientation angle workspace when the reference point on the end-effector moves along a non-radial direction are also discussed. A program is developed to calculate orientation angle workspaces and output variation curves of orientation angle workspace and key data within the position workspace. The approach and program in this paper can be used for fast calculation and identification of the variation rule of the orientation angle workspace of any given planar serial three-link manipulator on the basis of its link parameters, and for the design of a highly dexterous serial manipulator with proposed link relations. Supported by the Natural Science Foundation of Shanxi Province (Grant No. 20041070)     

Hybrids perfluorosulfonic acid ionomer and silicon oxide membrane for application in ion-exchange polymer-metal composite actuators

This paper reports a new technique to fabricate an ion-exchange polymer-metal composite (IPMC) actuator. This technique is based on a hybrid organic-inorganic composite membrane. In the fabrication course, silica oxide particles, prepared from hydrolysis of tetraethyl orthosilicate in situ with sol-gel reaction, co-crystallize with perfluorosulfonate acid (PFSA) ionomer. Attenuated total reflectance fourier transform infrared spectroscopy (ATR-FTIR) analyses demonstrate that a highly water-saving hybrid mem...     

Restraint of mid-spatial frequency error in magneto-rheological finishing (MRF) process by maximum entropy method

In order to restrain the mid-spatial frequency error in magnetorheological finishing (MRF) process, a novel part-random path is designed based on the theory of maximum entropy method (MEM). Using KDMRF-1000F polishing machine, one flat work piece (98 mm in diameter) is polished. The mid-spatial frequency error in the region using part-random path is much lower than that by using common raster path. After one MRF iteration (7.46 min), peak-to-valley (PV) is 0.062 wave (1 wave =632.8 nm), root-mean-square (RM...