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排序方式: 共有599条查询结果,搜索用时 15 毫秒
61.
Xiaofang Jia Kosuke Minami Koichiro Uto Alice Chinghsuan Chang Jonathan P. Hill Jun Nakanishi Katsuhiko Ariga 《Advanced materials (Deerfield Beach, Fla.)》2020,32(4):1905942
There is a growing interest in the development of dynamic adaptive biomaterials for regulation of cellular functions. However, existing materials are limited to two-state switching of the presentation and removal of cell-adhesive bioactive motifs that cannot emulate the native extracellular matrix (ECM) in vivo with continuously adjustable characteristics. Here, tunable adaptive materials composed of a protein monolayer assembled at a liquid–liquid interface are demonstrated, which adapt dynamically to cell traction forces. An ultrastructure transition from protein monolayer to hierarchical fiber occurs through interfacial jamming. Elongated fibronectin fibers promote formation of elongated focal adhesion structures, increase focal adhesion kinase activation, and enhance neuronal differentiation of stem cells. Cell traction force results in spatial rearrangement of ECM proteins, which feeds back to alter stem cell fate. The reported biomimetic adaptive liquid interface enables dynamic control of stem cell behavior and has potential translational applications. 相似文献
62.
Kazuaki Katagiri Shinya Honda Sayaka Minami Daiki Kimu Shimpei Yamaguchi Takuya Ehiro 《先进材料力学与结构力学》2020,27(18):1541-1550
Abstract The I-shaped cross-sectional beam of CFRP (CFRP I-beam) is usually manufactured by the continuous protrusion method. Carbon fibers can only be arranged in the longitudinal direction. The CFRP I-beam with arbitrary arrangement of carbon fiber was manufactured with applying the electro-activated deposition molding method. The carbon fiber fabric was immersed in the deposition solution and energized, epoxy resin precipitated around carbon fiber and impregnated. The resin-impregnated fabric was installed to the mold, and the CFRP I-beam was fabricated. The CFRP I-beam was subjected to three-point bending tests, and the relationship between load-deflection was simulated by finite-element analysis. 相似文献
63.
Usami K. Igarashi M. Minami F. Ishikawa T. Kanzawa M. Ichida M. Nogami K. 《Solid-State Circuits, IEEE Journal of》1998,33(3):463-472
This paper describes an automated design technique to reduce power by making use of two supply voltages. The technique consists of structure synthesis, placement, and routing. The structure synthesizer clusters the gates off the critical paths so as to supply the reduced voltage to save power. The placement and routing tool assigns either the reduced voltage or the unreduced one to each row so as to minimize the area overhead. The reduced supply, voltage is also exploited in a clock tree to reduce power. Combining these techniques together, we applied it to a media processor chip. The combined technique reduced the power by 47% in random-logic modules and by 73% in the clock tree, while keeping the performance 相似文献
64.
Masaki Oiwa Shunsuke Minami Kenichiro Tsuji Noriaki Onodera Masatoshi Saruwatari 《Optical Fiber Technology》2010,16(1):63-71
We propose and experimentally demonstrate the temporal-Talbot-effect (TTE)-based preprocessing for the pattern-effect reduction in the all-optical clock recovery using a semiconductor-optical-amplifier (SOA)-based fiber ring laser (SOA-FRL). The TTE-based preprocessing successfully reduced the pattern effects of the recovered clock pulses, so that the 10-GHz clear optical clock pulses were recovered from a 10-Gbit/s return-to-zero on–off keying (RZ-OOK) pseudo-random bit sequence (PRBS) optical signal. “Peak variation” and “Pattern-dependent intensity noise (PDIN)” were proposed and were utilized as parameters to quantitatively evaluate the pattern effects, from which recovered clock pulses suffer, in the temporal domain and the frequency domain, respectively. Peak variation was reduced from 77.2% to 36.2%, and PDIN was improved from ?103 dBc/Hz to ?110 dBc/Hz with the aid of the TTE-based preprocessing. Furthermore, we examined the tolerance of the proposed technique by intentionally deviating the input signal’s bit-rate by ±190 Mbit/s (±2% of the bit-rate) from the optimum condition for the TTE. As compared with the PDIN value for the pulse train obtained by the direct injection of the non-processed signal into the SOA-FRL, the PDIN of the recovered clock pulses using the preprocessed signal indicated improvements over the entire measurement range of ±190 Mbit/s, which corresponds to the wavelength-dispersion deviation of ±56 ps/nm (±4% of the wavelength-dispersion applied to the input signal) from the optimum value. 相似文献
65.
Modeling of NBTI saturation effect and its impact on electric field dependence of the lifetime 总被引:1,自引:0,他引:1
H. Aono E. Murakami K. Okuyama A. Nishida M. Minami Y. Ooji K. Kubota 《Microelectronics Reliability》2005,45(7-8):1109-1114
Negative Bias Temperature Instability of pMOSFETs is investigated under various stress gate voltages and temperatures. It is shown that degradation tends to saturate and the dependence of lifetime on electric field (Eox) is expressed as a power-law of Eox. We propose new empirical and kinetic models. The Eox dependence of the lifetime described by the power-law is derived from our empirical model describing the saturation of degradation. Moreover, our kinetic model explains the saturation behavior. 相似文献
66.
In 1996, the authors proposed a novel method to prepare micron-sized, hollow cross-linked polymer particles. This method is based on the self-assembling of phase separated polymer at interface with water, which was named SaPSeP method, formed by suspension polymerization of divinyl monomer in toluene droplet dissolving previously polystyrene. The SaPSeP method was developed to be applicable to polyaddition reaction system of epoxy resin with diamine. The presence of PS dissolving in epoxy/diamine/toluene droplets promotes the phase separation of the epoxy resin reacted with the diamine. The epoxy resin molecules tend to adsorb at the interface of the droplets. These points were accord with the required conditions for the preparation of hollow particle by the SaPSeP method. Cured epoxy resin particles having one hollow were successfully prepared by the polyaddition reaction in the dispersed system of Epikote 806/630/604, of which equivalent ratio was 5/4/1. 相似文献
67.
M. Cai P.K. Kaiser H. Morioka M. Minami T. Maejima Y. Tasaka H. Kurose 《International Journal of Rock Mechanics and Mining Sciences》2007,44(4):550-564
Acoustic emission (AE) and microseismic (MS) events are indicators of rock fracturing or damage as the rock is brought to failure at high stress. By capturing the AE/MS events, underground excavation induced rock mass degradation or damage can be located and evaluated. A better understanding of the extent and shape of the excavation damaged zone (EDZ) or yield zone around caverns helps to arrive at safe and economic design and construction of the caverns. For this purpose, one needs to understand the AE mechanism associated with the excavation process.In the present study, a coupled numerical method is used to study AE at the Kannagawa underground powerhouse cavern in Japan. Two codes, Fast Lagrangian Analysis of Continua (FLAC), a finite difference code and Particle Flow Code (PFC), a distinct element code, are coupled. The motive to apply the FLAC/PFC coupled approach is to take advantage of each modeling scheme while at the same time minimizing the requirement for computational resources. The coupling is realized through an exchange of displacements, velocities, and forces in each cycling step. The rock mass surrounding an AE sensor is modeled using PFC and the remaining rock mass is modeled with FLAC to consider the geological complexity and the excavation sequence. In this manner, the AE activities at AE sensor locations of the Kannagawa cavern were simulated and found to be in good agreement with field monitoring results. This approach takes account of stress redistribution and provides stress and displacement patterns in the rock mass that are consistent with AE observations for excavation design. The observed AE activities in the rock mass can thus be utilized to assess the effectiveness of the rock support system and the overall stability of the cavern. 相似文献
68.
69.
Experimental investigations have been carried out for combined convective flows of air induced around uniformly heated, horizontal cylinders. Three cases of aiding, opposing, and cross flows were examined. The experiments covered the ranges of the Reynolds and modified Rayleigh numbers of Red=50 to 900 and Rad*=5×104 to 3×106. The flow fields around the cylinders were visualized with smoke. The results showed that separation points gradually shift from those of the forced convection to the top edge of the cylinder with increasing wall heat fluxes. The local heat transfer coefficients of the cylinders were also measured. Although the local coefficients show complex variations with the forced flow velocities and the wall heat fluxes, the overall coefficients become higher than those estimated from pure forced and natural convections throughout the cases of aiding, opposing, and cross flows. Moreover, it was confirmed that the overall Nusselt numbers as well as the separation points can be predicted with the non‐dimensional parameter (Grd*/NudRed2). © 2007 Wiley Periodicals, Inc. Heat Trans Asian Res, 36(8): 474–488, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/htj.20180 相似文献
70.
K Hisamatsu S Iwamori K Minami K Tanabe K Ota H Akiyama 《Canadian Metallurgical Quarterly》1997,24(10):1327-1330
A 44-year-old premenopausal woman having local recurrence and pleural and bone metastases of breast cancer was treated with aromatization inhibition in combination with Luteinizing Hormone-releasing Hormone (LH-RH) agonist. The dominant site of metastasis was a painful local lesion invading the chest wall. A partial response by reducing the size of the local lesion was attained 3 months after initiation of treatment. This result suggested that treatment using aromatization inhibition in combination with LH-RH agonist would be effective in premenopausal breast cancer. To confirm the effectiveness of this treatment, comparative study between aromatization inhibition in combination with LH-RH agonist aromatization inhibition alone and anti-estrogen in combination with LH-RH agonist are needed. 相似文献