Changes in lycopene and beta carotene contents in aril and oil of gac fruit during storage

Gac fruits were physically measured and stored under ambient conditions for up to 2 weeks to observe changes in carotenoid contents (lycopene and beta carotene) in its aril. Initial concentrations in the aril of lycopene were from 2.378 mg/g fresh weight (FW) to 3.728 mg/g FW and those of beta carotene were from 0.257 to 0.379 mg/g FW. Carotenoid concentrations in the aril remained stable after 1 week but sharply declined after 2 weeks of storage. Gac oil, pressed from gac aril, has similar concentrations of lycopene and beta carotene (2.436 and 2.592 mg/g, respectively). Oil was treated with 0.02% of butylated hydroxytoluene, or with a stream of nitrogen or untreated then stored in the dark for up to 15 or 19 weeks under different temperatures (5 °C, ambient, 45 and 60 °C). Lycopene and beta carotene in control gac oil degraded following the first-order kinetic model. The degradation rate of lycopene and beta carotene in the treated oil samples were lower than that in the control oil but the first-order kinetic was not always followed. However, both lycopene and beta carotene degraded quickly in gac oil with the first-order kinetic under high temperature conditions (45 and 60 °C) regardless of the treatments used.     

Recent large-diameter tunnel construction in Singapore using sprayed concrete linnings

Sprayed Concrete Lining (SCL) or the New Austrian Tunnelling Method (NATM) has had limited exposure in Singapore. Previously this has been restricted to excavations of less than 6 metres inside diameter in the boulder clay and decomposed granite. For the North East Line Project (NELP) a section of SCL tunnel was constructed as part of the tunnelling works on Contract 710. This paper describes the design, planning, and construction issues of twin 8.4-metre inside diameter crossover tunnels spaced less than one diameter apart constructed in the Jurong Formation. In addition, the construction of a SCL tunnel in the Old Alluvium, is also described. This tunnel is an advance tunnel for the future Deep Tunnel Sewage Scheme (DTSS) and is being constructed as part of the NELP Contract 705 Works. Details of the Jurong Formation and Old Alluvium are given together with their geotechnical characteristics, which played a major role in the selection of temporary support methods used and the behaviour of the ground during tunnelling. The planning and design issues concentrate on aspects to ensure overall integrity and stability of both SCL projects. The success of various construction techniques utilised to construct the tunnels safely is discussed and a summary of the ground movements is presented.     

Upconversion luminescence of Gd2O3:Er3+ and Gd2O3:Er3+/silica nanophosphors fabricated by EDTA combustion method

Gd_2O_3:Er~(3+) nanophosphors were fabricated by the combustion method in presence of Na_2 ethylene diamine tetra acetic acid(EDTA-Na_2) as fuel at not high temperature(≤350℃) within a very short time of 5 min.The added concentration of Er~(3+)ions in Gd_2O_3 matrix was changed from 0.5 mol% to 5.0 mol%.The X-ray diffraction pattern of samples indicates the monoclinic structure of Gd_2O_3:Er3+.The morphology and chemical composition analysis of the Gd_2O_3:Er~(3+) samples are characterized by a field emission scanning electron microscope(FESEM) and a Fourier-transform infrared spectrometer(FTIR).The photoluminescence(PL),photo luminescence excitation(PLE) and upconversion(UC) at room temperature of the prepared materials with different concentrations of Er~(3+) were investigated.The PL of Gd_2O_3:Er~(3+)nanomaterials are shown in visible at 545,594,623,648,688 nm under excitation at 275 nm.The emission bands from transitions of Er~(3+) from ~2P_(3/2) to ~4F_(9/2) are observed,UC luminescent spectra of the Gd_2O_3:Er~(3+)/silica nanocomposites under 976 nm excitation show the bands at 548 and 670 nm.The influence of excitation power at 980 nm for transitions were measured and calculated.The results indicate that the upconversion process of Gd_2O_3:Er~(3+)/silica is two photons absorption mechanism.The low temperature dependence of UC luminescent intensities of the main bands of Gd_2O_3:Er~(3+)was investigated towards development of a nanotemperature sensor in the range of 10-300 K.     

Multi-extremum-modified response basis model for nonlinear response prediction of dynamic turbine blisk

For the nonlinear dynamic analyses of complex mechanical components, it is necessary to apply efficient modeling framework to reduce computational burden. The accurate surrogate model for approximating the nonlinear responses of several failures is a vital issue to provide robust and safe design conditions in complex engineering applications. In this paper, two different Modified multi-extremum Response Surface basis Models (MRSM) are proposed for dynamic nonlinear responses of failure capacities for turbine blisk responses. The proposed MRSM is established using two regression processes including regressed the input variables by linear or exponential basis functions in first calibrating phase and regressed the second-order polynomial basis function using inputs data provided by first stage in second calibrating procedure. A sensitivity analysis using MRSM is proposed to consider the variation of input variables on the nonlinear responses. In the sensitivity analysis procedure, the effects of input variables are evaluated using the calibrating results given from the first regressed process. To evaluate the performance of the proposed MRSM, three multi-extremum failure modes including radial deformation of compressor blisk, maximum strain, and stress of compressor blade and disk are considered. the prediction of MRSM of nonlinear responses for Thermal-fluid–structure system with dynamical nonlinear finite-element analyses is compared with response surface method (RSM) and artificial neural network (ANN). The predicted results of modeling approaches showed that the sensitivity analysis based on MRSM accurately provided the effective degree for input variables. The gas temperature has the highest effects on nonlinear responses of turbine blisk which is followed by angular speed and material density. The MRSM combined with basic exponential function performs better than other models, while the MRSM coupled with linear function is more accurate than ANN and RSM. The proposed MRSM models have illustrated the accurate and efficient framework for approximating dynamic structural analysis of complex components.

     

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury

Hemolysis is known to cause acute kidney injury (AKI). The iron regulatory hormone hepcidin, produced by renal distal tubules, is suggested to exert a renoprotective role during this pathology. We aimed to elucidate the molecular mechanisms of renal hepcidin synthesis and its protection against hemoglobin-induced AKI. In contrast to known hepatic hepcidin induction, incubation of mouse cortical collecting duct (mCCD_cl1) cells with IL-6 or LPS did not induce Hamp1 mRNA expression, whereas iron (FeS) and hemin significantly induced hepcidin synthesis (p < 0.05). Moreover, iron/heme-mediated hepcidin induction in mCCD_cl1 cells was caused by the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, as indicated by increased nuclear Nrf2 translocation and induced expression of Nrf2 downstream targets GCLM (p < 0.001), NQO1 (p < 0.001), and TXNRD1 (p < 0.005), which could be prevented by the known Nrf2 inhibitor trigonelline. Newly created inducible kidney-specific hepcidin KO mice demonstrated a significant reduction in renal Hamp1 mRNA expression. Phenylhydrazine (PHZ)-induced hemolysis caused renal iron loading and oxidative stress in both wildtype (Wt) and KO mice. PHZ treatment in Wt induced inflammatory markers (IL-6, TNFα) but not Hamp1. However, since PHZ treatment also significantly reduced systemic hepcidin levels in both Wt and KO mice (both p < 0.001), a dissection between the roles of systemic and renal hepcidin could not be made. Combined, the results of our study indicate that there are kidney-specific mechanisms in hepcidin regulation, as indicated by the dominant role of iron and not inflammation as an inducer of renal hepcidin, but also emphasize the complex interplay of various iron regulatory mechanisms during AKI on a local and systemic level.     

Adaptation to climate change for food security in the lower Mekong Basin

Variability in water cycles driven by climate change is considered likely to impact rice production in the near future. Rice is the main staple food for the population in the lower Mekong Basin and the demand for food is expected to grow due to increase in population. This paper examines the impact of climate change on rice production in the lower Mekong Basin, evaluates some widely used adaptation options, and analyses their implications for overall food security by 2050. Climate change data used in the study are the future climate projection for two IPCC SRES scenarios, A2 and B2, based on ECHAM4 General Circulation Model downscaled to the Mekong region using the PRECIS (Providing Regional Climates for Impact Studies) system. In general, the results suggest that yield of rainfed rice may increase significantly in the upper part of the basin in Laos and Thailand and may decrease in the lower part of the basin in Cambodia and Vietnam. Irrigated rice may not be affected by climate change if increased irrigation requirements are met. Negative impact on the yield of rainfed rice can be offset and net increase in yield can be achieved by applying widely used adaptation options such as changing planting date, supplementary irrigation and increased fertilizer input. Analysis of the projected production, considering population growth by 2050, suggests that food security of the basin is unlikely to be threatened by the increased population and climate change, excluding extreme events such as sea level rise and cyclones.     

Enhanced Magnetization in CoFe2O4 Through Hydrogen Doping

Magnetic spinel oxides have attracted extensive research interest due to their rich physics and wide range of applications. However, these materials invariably suffer suppressed magnetization, due to structural imperfections (e.g., disorder, anti-site defects, etc.). Herein, a dramatic enhanced magnetization is obtained with an increasement of 5 µ_B/u.c in CoFe₂O₄ (CFO) through ionic liquid gating induced hydrogen doping. The intercalated hydrogen ions lead to both distinct lattice expansion of ≈0.7% and notable Fe valence state reduction through electron doping, in which ≈17% Fe³⁺ is reduced into Fe²⁺. These facts collectively trigger a site-specific spin-flip on tetrahedrally coordinated Co²⁺ sites that enhances the net ferrimagnetic moment nearly to its theoretical maximum for perfect CFO.     

Adaptive neural network hierarchical sliding mode control for six degrees of freedom overhead crane

This paper presents an effective control method for three-dimensional (3D) overhead cranes with six degrees of freedom (DOF). Two payload swings and an axial payload oscillation should be minimized besides driving the bridge, trolley, and hoisting drum to bring the payload to the desired position in space. First, a novel 3D-6DOF crane model is developed, where the sixth degree of freedom is axial cargo oscillation that has never been considered in previous studies. A controller is then designed using the hierarchical sliding mode control method. Moreover, a radial basis function neural network (RBFNN) is used to approximate the system's unknown dynamic model accurately. According to the Lyapunov principle, a control law and an updated law for the neural network's weight matrices are designed to ensure the stability of the closed-loop system. Simulation results on Matlab software show the proposed approach's effectiveness, such as smaller swing, minor axial oscillation, and precise position as desired.