A STOCHASTIC CHARACTERIZATION OF THE MACHINE TOOL WORKPIECE SYSTEM IN BTA OEEP HOLE MACHINING Part I: Mathematical Modelling and Analysis

A three dimensional model of the BTA deep-hole machining system is presented by modelling each of the components separately and later combining to represent the total system. A model for the interaction between the workpiece and the cutting tool is also included. Such a model can determine the response of any component of the machine tool as well as the individual influence on the system performance. Based on this, physical models representing the three working methods in the BTA process can be studied, from which stochastic differential equations are derived to represent the resultant force system on the machine tool

A physical model for the stationary workpiece and rotating cutting tool working method is developed. The assumed modes method along with the Lagrange' equation is used to obtain the stochastic differential equation to represent the influence of axial force and torque, in order to obtain the response of the system under the action of the axial force and torque to predict the stability behaviour.     

Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex

Infection by human immunodeficiency virus type 1 (HIV-1) is often complicated by a variety of neurological abnormalities. The most common clinical syndrome, termed acquired immunodeficiency syndrome (AIDS) dementia complex, presents as a subcortical dementia with cognitive, motor, and behavioral disturbances and is unique to HIV-1 infection. The pathogenesis of this syndrome is poorly understood but is believed to involve interactions among virally infected macrophages/microglia, astrocytes, and neurons. In this study, we show that exposure of primary rat and human astrocytes to heat-activated HIV-1 virions, or to eukaryotically expressed HIV-1 and HIV-2 envelope glycoproteins (gp120) stimulates amiloride-sensitive Na+/H+ antiport, potassium conductance, and glutamate efflux. These effects are blocked specifically by amiloride, an inhibitor of Na+/H+ antiport and by the selective removal of gp120 with immobilized monoclonal antibody. As a result of modulation of astrocytic function by gp120, the ensuing neuronal depolarization and glutamate exposure could activate both voltage-gated and N-methyl-D-aspartate-regulated Ca2+ channels, leading to increases in intraneuronal Ca2+ and neuronal death. These findings implicate the astrocyte directly in the pathogenesis of AIDS dementia complex.     

Effect of sillimanite beach sand composition on mullitization and properties of Al<Subscript>2</Subscript>O<Subscript>3</Subscript>-SiO<Subscript>2</Subscript> system

Mullite was developed by reaction sintering of sillimanite beach sand and calcined alumina. Two varieties of sillimanite beach sand viz. S and Z having different compositions were selected. Synthesis and properties of mullite were very much dependent on the sillimanite beach sand composition. Presence of higher amount of impurities in the Z-variety of sillimanite sand favours the densification by liquid phase formation. Presence of zircon in Z-variety increases the hardness and fracture toughness. Alumina addition improves the mechanical/thermomechanical properties of the samples. Mullite retains the usual orthorhombic habit of sillimanite. Rounded to sub rounded zirconia dispersed within the mullite matrix of the sample ZA is noticed.     

Crystal plasticity modeling of deformation and creep in polycrystalline Ti-6242

This paper develops an experimentally validated computational model based on crystal plasticity for the analysis of two-phase α/β Ti-6242 polycrystalline alloys. A rate-dependent elastic-crystal plasticity model is incorporated in this model to accommodate anisotropy in material behavior and tension-compression asymmetry inherent to this alloy. A combination of microtesting, orientation imaging microscopy, computational simulations, and minimization process, involving genetic algorithms, is implemented in this study for careful characterization and calibration of the material parameters. Size effects are considered in this analysis through a simple scaling process. A homogenized equivalent model of the primary α with transformed β colonies is developed for incorporation in the Ti-6242 FE model. The polycrystalline Ti-6242 computational model incorporates accurate phase volume fractions, as well as statistically equivalent orientation distributions to those observed in the orientation imaging microscopy scans. The effects of orientation, misorientations, and microtexture distributions are investigated through simulations by this computational model. The model is used to simulate constant strain rate and creep tests in compression and tension, and the results are compared with experiments. The effects of microstructure and creep-induced load-shedding on the localization of microstructural stresses and strains are studied for potential crack initiation criteria.     

Mössbauer Study of the Influence of Fe-Si-N Liquid in the Synthesis of β-Si3N4 from Silica

Mössbauer spectra of the products obtained by carbothermal reduction and distribution of silica in the presence of iron in the temperatures range 1200^o to 1540^o were studied. The preponderance of β- Si₃N₄ over the α form at a higher reaction temperature were assumed to be related to the formation of an Fe-Si-N liquid. The liquid did not alter its composition with the variation of reduction-temprature, Iron had no effect on the reaction mechanism below 1300^oC.     

Studies on jute–asphalt composites

The tensile properties of jute make it a suitable raw material for asphalt overlay (A/O) fabric. In this study, the thermal stability of jute under conditions of asphalt overlaying process was investigated and the compatibility of jute with asphalt was assessed through experimentation on jute–asphalt composites under mechanical and hygral loads. Fourier transform infra red (FTIR) spectroscopic study revealed probable chemical bonding between jute and asphalt. The test for ascertaining the capability of asphalt encasement for protecting jute against biodegradation under enzymatic attack was found positive. A 6‐month hygral treatment, of the jute–asphalt composite, showed significant increase in modulus of the material. The results indicate that although the strength of jute deteriorates by about 10% under asphalt overlaying condition, the overall tensile behavior of jute fabric–asphalt composite material is considerably superior to that of the pure jute fabric, even under biological and extended hygral loading conditions. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci 2008     

A study on dynamic friction of different spun yarns

This article presents the results from a study of yarn-to-yarn (YY) and yarn-to-metal (YM) frictions conducted on ring, rotor, air-jet, and open-end friction (OE friction) spun yarns at different relative speeds and input tensions. The results indicate that the behavior of frictions for YY is different than that of YM. In case of YY friction, OE friction yarn shows maximum friction followed by rotor, air-jet, and ring spun yarns; however, a reverse order is noticed for YM friction. The relative speed and input tension have significant influence on the frictional behavior of spun yarns. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep

From October 1988 to January 1992, nine isolates of Pseudomonas aeruginosa carrying transferable plasmids encoding imipenem-hydrolyzing beta-lactamase (pI = c. 9.5) were recovered from nine different patients in a neurosurgical ward of a hospital in Japan. The beta-lactamase activities of the sonicated extracts from the transconjugants were inhibited by EDTA and this was partially reversible by the addition of zinc cation. The substrate specificity and pI of the beta-lactamase were similar to those of the metallo beta-lactamases from P. aeruginosa and Serratia marcescens TN9106. All strains were resistant to imipenem, carbenicillin and antipseudomonal cephems including ceftazidime, cefsulodin, cefpirome, while four and five strains were susceptible to piperacillin and aztreonam, respectively. Both low level imipenem resistance and high level cephem resistance were co-transferred with the production of metallo beta-lactamase, while resistance to piperacillin, aztreonam, and high level imipenem-resistance were not selected. Production of chromosomal cephalosporinase in piperacillin resistant strains was derepressed, and production of outer membrane protein of D2 was diminished in highly imipenem resistant strains. Six strains were isolated in 1991, and the amounts of antipseudomonal agents, especially imipenem, used in the neurosurgical ward increased markedly in this year. Only three of the nine isolates had the same serotype, pyocin type and phage type. Our results suggest that the repeated isolation of imipenem and cephem-resistant P. aeruginosa producing metallo beta-lactamase was related to the high usage of antipseudomonal beta-lactam antibiotics such as imipenem, and was exacerbated by the dissemination of a plasmid.     

Enumeration of minimal cutsets from matrix representation of directed/undirected networks

This paper describes an algorithm for finding the minimal cutsets between a specified source and terminal nodes of directed/undirected networks. Adjacent nodes of a source node/merged node are determined by the collection of node numbers of columns corresponding to non-zero elements of the first row of the adjacency matrix to form the reduced adjacency matrix (RAM) corresponding to merged nodes. Connectivity of RAM has been checked to obtain the minimal cutsets.     

Premature separation of centromere and aneuploidy: an indicator of high risk in unaffected individuals from familial breast cancer families?

OBJECTIVES: Injury is the leading cause of death in the male working population of Brazil. An important fraction of these deaths are work related. Very few cohort studies of steel workers, and none from developing countries, have reported on mortality from injuries. This paper analyses mortality from work and non-work related injuries among Brazilian steel workers. METHODS: Deaths during employment from 1 January 1977 to 30 November 1992 were analysed in a cohort of 21,816 male steel workers. Mortality rates specific for age and calendar year among the workers were compared with those of the male population of the state where the plant is located. Work related injuries were analysed by comparing the mortality rates for different subgroups of the cohort. RESULTS: The number of deaths (391) was less than half that expected based on death rates of the general population. Over 60% (242) of deaths were due to injuries. Mortality from most causes was substantially below that in the general population, but that from unintentional injury, was 50% above that of the general population. Standardised mortality ratios (SMRs) were highest for the youngest and the oldest employees and for labourers and clerical workers. Mortality from motor vehicle injury was twice that expected from population rates (SMR = 209, 95% confidence interval (95% CI) 176-244). There was a 67% fall in the age adjusted mortality from occupational injuries in the study period. CONCLUSION: The healthy worker effect in this cohort was greater than that commonly found in studies of occupational groups in developed countries, probably because of a greater socioeconomic gap between employed and unemployed populations in Brazil, and unequal distribution of health care resources. Mortality was especially high for motor vehicle injuries. The fall in mortality from occupational injuries during the study period was probably due to improvement in safety standards, increased automation, and better medical care. There is a need to investigate risk factors for unintentional injuries among steel workers, especially those due to motor vehicle injuries. Prevention of occupational and nonoccupational injuries should be a main priority in Brazil.