流谱心率系统在电动自行车上的应用

介绍了心率监控系统在电动自行车上的应用,在骑行电动自行车过程中,通过车把传感器进行心率实时监控,当骑行人心率体征发生变化时系统可以及时报警,减少因为骑行人体征变化引起的交通事故,从而引领人们健康生活的理念。     

Carrots and sticks: A comprehensive business model for the successful achievement of energy efficiency resource standards

U.S. utilities face significant financial disincentives under traditional regulation in aggressively pursuing cost-effective energy efficiency. Regulators are considering some combination of mandated goals and alternative utility business model components to align the utility’s business and financial interests with state and federal energy efficiency public policy goals. We analyze the financial impacts of an Energy Efficiency Resource Standard on an Arizona electric utility using a pro-forma utility financial model, including impacts on utility earnings, ROE, customer bills and rates. We demonstrate how a viable business model can be designed to improve the business case while retaining sizable benefits for utility customers.     

可回收式锥形肝静脉支架的动物实验研究

【摘要】 目的 通过动物实验评估可回收式锥形肝静脉支架的可行性、安全性及稳定性,探讨支架回收最佳时间。方法 健康家猪24头,随机分为4组,每组6头。全身麻醉下经右颈内静脉入路接受肝中静脉可回收式锥形支架置入术,术后3、7、11、15 d分别接受支架回收。采用t检验对比各组支架置入后、回收前所测得的支架内血流压力变化差异。采集支架中段相邻血管组织标本作病理学检查,测量计算新生血管内膜厚度,单因素方差分析对比各组间新生内膜厚度差异。结果 24枚支架均成功置入,技术成功率100%;支架回收技术成功率为50%（12/24）。肝中静脉内压力测量显示,3 d组支架置入后与回收前比较,差异无统计学意义（P＞0.05）;7 d组、11 d组、15 d组支架置入后与回收前比较,差异有统计学意义（P＜0.05）。各组间支架中段相邻组织新生内膜平均厚度两两比较,差异均有显著统计学意义（F＝338.29,P＜0.001）。结论 可回收式锥形支架置入家猪肝静脉安全、可行,其最佳安全回收时间为3 d,最长不宜超过7 d。

     

高精度伺服系统基于Pade近似的数字前馈控制器

针对指令超前信息未知的情况,提出一种基于Pade近似原理的数字前馈控制器。以某电机伺服系统为例进行仿真,结果表明了本控制器的有效性。     

Delineation of Subsea Freshwater Extension by Marine Geoelectromagnetic Soundings (SE Mediterranean Sea)

This study presents a novel application of marine geoelectromagnetic technique, in an attempt to delineate freshwater extension of the coastal sub-aquifers beneath the SE Mediterranean Sea, along central Israel. The novel marine Ex-Bz time domain electromagnetic (TDEM) geophysical method was applied, demonstrating high sensitivity to the presence of sub-seafloor electrically resistive structures up to several kilometers offshore (shallow marine environment). The study included 19 marine measurements located offshore between Ashdod in the south to Tel-Aviv in the north, where a previous onshore study detected fresh groundwater below seawater intrusion at the coast line. The offshore measurements were conducted to distances of up to 3 km from the shoreline. It was found that the lower sub-aquifer contains fresh groundwater (resistivity >10 Ω-m) to a distance of 2.8 km offshore along the 30 km strip, and is probably constrained by lateral geo-facial changes.     

Pulmonary delivery of nanoparticles of insoluble, iodinated CT X-ray contrast agents to lung draining lymph nodes in dogs

Lung cancer continues to be a leading cause of death around the world. Staging of this disease is critically dependent upon the involvement or noninvolvement of the lymph nodes which drain the region of lung containing the lesion/tumor. Palpation, unenhanced CT, and lymph node excision (i.e., mediastinectomy) are currently used to ascertain the status of these regional draining lymph nodes. The work reported herein details the first efforts toward the pulmonary instillation of iodinated nanoparticles for contrast-enhanced CT of lung draining lymph nodes. The data reflect the impact of dose, time post instillation, and formulation (surfactant) upon the observed CT enhancement of the tracheobronchial lymph nodes of beagle dogs. In addition, initial safety is discussed with both macroscopic and microscopic observations. The results indicate that pulmonary instillation of small volumes of iodinated nanoparticles could be successfully used to aid staging of lung cancer by CT imaging.     

The P300 as an electrophysiological probe of alcohol expectancy.

Language-based measures indicate that alcohol expectancies influence alcohol consumption. To relate these measures to brain actions that precede verbal output, the P300 component of the Event-related potentials (ERPs) was used to detect violations of individually held alcohol expectancies. As predicted, P300 amplitude elicited by negative alcohol expectancy stimuli was positively correlated with endorsement of positive/arousing alcohol expectancies on the language-based measures, such that the higher an individual's positive/arousing expectancies, the larger was the P300 elicited by negative alcohol expectancy stimuli. These results demonstrated concordance between language-based measures of alcohol expectancies and electrophysiological probes of expectancy. While it remains unknown whether these expectancy processes are integral to decision pathways that influence consumption, these findings suggest that such processing can occur very quickly outside of conscious deliberation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5,5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells

Rapidly growing knowledge about the nature and behaviour of breast cancer has led to many treatment modalities. Consequently, the possibilities of individualizing the treatment of breast cancer increase. The major tool for the determination of an optimal treatment plan is the estimation of the extent of the disease: in other words, staging. As a consequence, together with the expected result of the treatment, the stage of the disease gives information on the prognosis of the patient. Current staging systems insufficiently describe the clinically important features of breast cancer with respect to management and outcome: local and regional extent, invasiveness, aggressiveness, the state of dissemination, and the effectiveness of different treatment modalities. For staging of the local and regional extent, histology plays a prominent role and should be incorporated in future staging systems. Histological workup therefore needs standardisation. Histological parameters as tumour size, grade, nodal status, and vascular invasion are also the most important prognostic factors. Many so-called biological prognostic factors are related to the invasiveness and aggressiveness (metastatic potential) of the tumour, and therefore to the prognosis of the patient. However, these factors do not necessarily predict the effectiveness of certain systemic treatments. Only if the biological foundation of a prognostic factor is completely clarified can treatment be based on this knowledge, and the factor will become a predictor for the treatment effect. Many "biological" prognostic factors do not fulfil this main criterion and are therefore not useful for clinical decision making. A clinically useful staging system covers three primary aims: (1) to guide locoregional treatment, (2) to prognosticate the chance of survival, and (3) to indicate who needs what kind of adjuvant treatment. For the conception of a new staging system the following steps should be taken: standardization of all aspects of histology, identification of regional nodal involvement, and validation of prognostic factors with respect to their predictive value to treatment outcome.