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排序方式: 共有163条查询结果,搜索用时 0 毫秒
31.
Tovilovic G Zogovic N Harhaji-Trajkovic L Misirkic-Marjanovic M Janjetovic K Vucicevic L Kostic-Rajacic S Schrattenholz A Isakovic A Soskic V Trajkovic V 《ChemMedChem》2012,7(3):495-508
The protective ability of novel arylpiperazine-based dopaminergic ligands against nitric oxide (NO)-mediated neurotoxicity is investigated. The most potent neuroprotective arylpiperazine identified during the study was N-{4-[2-(4-phenyl-piperazin-1-yl)ethyl]-phenyl}picolinamide, which protected SH-SY5Y human neuron-like cells from the proapoptotic effect of NO donor sodium nitroprusside (SNP) by decreasing oxidative stress, mitochondrial membrane depolarization, caspase activation and subsequent phosphatydilserine externalization/DNA fragmentation. The protective effect was associated with the inhibition of proapoptotic (JNK, ERK, AMPK) and activation of antiapoptotic (Akt) signaling pathways, in the absence of interference with intracellular NO accumulation. The neuroprotective action of arylpiperazines was shown to be independent of dopamine receptor binding, as it was not affected by the high-affinity D?/D? receptor blocker butaclamol. These results reported support the further study of arylpiperazines as potential neuroprotective agents. 相似文献
32.
Xiaohua Hu Gordana A. Cingara David S. Wilkinson Mukesh Jain PeidongWu Raja K. Mishra 《计算机、材料和连续体(英文)》2009,14(2):99-124
This work aims to understand the texture distribution in the localized necking band formed during uni-axial tension of AA5754 using an edge-constrained, plane strain post-necking FE model. The model domain is a long cross section of the band. Initial grain structure is mapped into the mesh from EBSD data using a modified Voroni-cell interpolation and considering pre-straining prior to localized necking. The material points in grains are assumed to exhibit isotropic elastoplastic behavior but have a relative strength in terms of Taylor factors which are updated by a Taylor-Bishop-Hill model. The predicted textures and gradients within the localized necking band correlate well with experimental measurements where large rigid body rotation and lattice spin are experienced due to geometric constraints and excessive deformation in the band. 相似文献
33.
This paper presents a novel two-stage class of decimation filters with superior spurious signal rejection performance around the so-called folding bands, i.e., frequency intervals whose signals get folded down to baseband due to decimation. The key idea to enhance signal rejection in the frequency domain lies on an effective way to place the zeros of a classical comb filter in the aforementioned folding bands. On the other hand, the paper provides a mathematical framework for designing two-stage multiplierless and nonrecursive structures of the proposed filters.Examples are provided to highlight the key steps in the design of the proposed filters. Moreover, the frequency behavior of the proposed filters in both baseband and stopband is compared with classical and generalized comb filters, and a droop compensator is proposed to counteract the passband distortion of the proposed filters. 相似文献
34.
Biosorption of nickel ions from aqueous solutions by natural and modified peanut husks: equilibrium and kinetics 下载免费PDF全文
Katerina Atkovska Burevska Hamdije Memedi Kiril Lisichkov Stefan Kuvendziev Mirko Marinkovski Gordana Ruseska Anita Grozdanov 《Water and Environment Journal》2018,32(2):276-284
The toxicity and non‐biodegradation of heavy metals, as well as their tendency to accumulate in the soils, water resources and the living organisms, makes them the significant environmental pollutants. Therefore, the reduction and elimination of heavy metal ions from aqueous systems is very important from the ecological, nutritional and environmental reasons. The aim of this study is to investigate whether the natural peanut husks, an agricultural waste, and their chemically modified form are capable to remove Ni(II) ions from aqueous solutions using batch method and to compare their efficiency. The effects of the mass of the natural peanut husks and the initial pH of the solution were studied to find the optimal conditions for maximal removal of Ni(II) ions. MATLAB/Curve Fitting Toolbox was implemented to determine the adequate adsorption isotherm as well as to optimise the equilibrium state of the investigated systems. 相似文献
35.
Bulk oxy(nitride) (Ga(1-x)Zn(x))(N(1-x)O(x)) is a promising photocatalyst for water splitting under visible illumination. To realize its solar harvesting potential, it is desirable to minimize its band gap through synthetic control of the value of x. Furthermore, improved photochemical quantum yields may be achievable with nanocrystalline forms of this material. We report the synthesis, structural, and optical characterization of nanocrystals of (Ga(1-x)Zn(x))(N(1-x)O(x)) with the values of x tunable from 0.30 to 0.87. Band gaps decreased from 2.7 to 2.2 eV over this composition range, which corresponded to a 260% increase in the fraction of solar photons that could be absorbed by the material. We achieved nanoscale morphology and compositional control by employing mixtures of ZnGa(2)O(4) and ZnO nanocrystals as synthetic precursors that could be converted to (Ga(1-x)Zn(x))(N(1-x)O(x)) under NH(3). The high quality of the resulting nanocrystals is encouraging for achieving photochemical water-splitting rates that are competitive with internal carrier recombination pathways. 相似文献
36.
Biljana Milutinović Gordana Stefanović Slobodan Milutinović Žarko Ćojbašić 《Clean Technologies and Environmental Policy》2016,18(6):1863-1875
The social aspect is very important in sustainability assessment of waste treatment technique, as well as making decision on their application and planning. In recent years, it is becoming evident that a waste treatment technique, which ignores social aspects, is doomed to failure. The most commonly used social indicators are: number of jobs created, level of social acceptance, public knowledge, public health etc. The most of them are qualitative and measuring the sustainability and quantifying the social dimension of sustainability are difficult tasks. This paper presents the application of fuzzy logic for evaluating the social indicator—level of social acceptance. The fuzzy set theory and fuzzy logic were used to develop a model for the evaluation of level of social acceptance, due to the lack of data, uncertainties, and qualitative character of indicators and also to provide effective way to include knowledge and gained experience on the process. A questionnaire was applied as instrument for data collection. The fuzzy model was verified using the city of Ni? as a case study. The results obtained using the developed fuzzy model, shows that the highest level of social acceptance in the city of Ni? is for recycling (57.47 %) and the lowest level of social acceptance is for incineration (17.74 %). The presented study suggests an innovative methodology for evaluation of level of social acceptance of certain waste treatment based on fuzzy logic approach and can be used for ranking of waste management scenarios in the sustainability assessment. 相似文献
37.
This article presents a review of glyph-based techniques for engineering visualization as well as practical application for the multivariate visualization process. Two glyph techniques, Chernoff faces and star glyphs, uncommonly used in engineering practice, are described, applied to the selected data set, run through the chosen optimization methods and user evaluated. As an example of how these techniques function, a set of data for the optimization of a heat exchanger with a microchannel coil is adopted for visualization. The results acquired by the chosen visualization techniques are related to the results of optimization carried out by the response surface method and compared with the results of user evaluation. Based on the data set from engineering research and practice, the advantages and disadvantages of these techniques for engineering visualization are identified and discussed. 相似文献
38.
Bituh T Marovic G Franic Z Sencar J Bronzovic M 《Journal of hazardous materials》2009,162(2-3):1199-1203
The contents of natural radionuclides (radium, uranium and potassium) were measured in the area of a phosphate fertilizer factory in central Croatia, as a part of extended and still ongoing monitoring program of radioactive contamination of human environment in Croatia that is performed by the Radiation Protection Unit of the Institute for Medical Research and Occupational Health in Zagreb. Activity concentrations in all analysed media (waste water, trickling water from piezometers, phosphogypsum deposit and final products) considerably fluctuated, especially in phosphogypsum and waste water. Mean (226)Ra activity concentration in waste phosphogypsum was measured to be 483+/-190 Bqkg(-1). Based on that value, it was estimated that 4 million m(3) of phosphogypsum that have been deposited up to now contain about 4.3 x 10(12) Bq, i.e. about 200 g of (226)Ra. However, effective dose for an adult that would be incurred by consumption of water from nearby wells was estimated to be 5.3+/-1.3 microSv. The results show that (226)Ra activities cause effective doses, which are below the recommended maximum as the estimated annual (226)Ra effective dose does not exceed 0.1 mSv as recommended by the World Health Organization. 相似文献
39.
Maurizio Avella Gordana Bogoeva-Gaceva Aleksandra Bužarovska Maria Emanuela Errico Gennaro Gentile Anita Grozdanov 《应用聚合物科学杂志》2008,108(6):3542-3551
Biodegradable thermoplastic-based composites reinforced with kenaf fibers were prepared and characterized. Poly(lactic acid) (PLA) was selected as polymeric matrix. To improve PLA/fibers adhesion, low amount of a proper reactive coupling agent, obtained by grafting maleic anhydride onto PLA, was added during matrix/fibers melt mixing. Compared with uncompatibilized composites, this compatibilization strategy induces a strong interfacial adhesion and a pronounced improvement of the mechanical properties. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 相似文献
40.
Gordana Ćirić-Marjanović Ivanka Holclajtner-Antunović Slavko Mentus Danica Bajuk-Bogdanović Dragana Ješić Dragan Manojlović Snežana Trifunović Jaroslav Stejskal 《Synthetic Metals》2010,160(13-14):1463-1473
Polyaniline (PANI) micro/nanostructures were synthesized by the external-template-free oxidative polymerization of aniline in aqueous solution of 12-tungstophosphoric acid (WPA), using ammonium peroxydisulfate (APS) as an oxidant and starting the oxidation of aniline from slightly acidic media (pH 5.4–5.9). The effect of the initial weight ratio of WPA to aniline on molecular structure, morphology, and physicochemical properties of polyaniline 12-tungstophosphate (PANI-WPA) was investigated by FTIR, Raman and inductively coupled plasma optical emission (ICP-OES) spectroscopies, elemental analysis, X-ray powder diffraction (XRPD), scanning and transmission electron microscopies (SEM and TEM), thermogravimetric analysis (TGA), differential thermal analysis (DTA), and conductivity measurements. The morphological change of polymerization products during a single polymerization process, from non-conducting submicro-/microspherical oligoaniline intermediates to semiconducting PANI-WPA consisted of self-assembled nanotubes and/or nanorods co-existing with submicro-/microspheres, has been revealed by SEM and TEM. The average diameter of nanorods in PANI-WPA samples decreased with increasing the initial WPA/aniline weight ratio. The incorporation of 12-tungstophosphate counter-ions into PANI matrix has been proved by FTIR, Raman and ICP-OES spectroscopies, TGA and DTA analysis. Electrical conductivity of PANI-WPA increased in the range (2.5–5.3) × 10?3 S cm?1 with the increase of the initial WPA/aniline weight ratio. The presence of branched structures and phenazine units besides the ordinary paramagnetic and diamagnetic emeraldine salt structural features in PANI-WPA was proved by FTIR and Raman spectroscopies. 相似文献