Nevoscopy: three-dimensional computed tomography of nevi and melanomas in situ by transillumination

The thickness of a malignant nevus has been found to be an important prognostic factor for patients with melanoma. We have designed a new method of imaging nevi that permits their thickness to be measured in situ. Using fiber optics directed into the surrounding skin, we transilluminate the nevus. Three images are picked up by a digitizing TV camera: the vertical image (90 degrees ), a glancing image (180 degrees ), and one at 45 degrees , obtained by using two front-silvered mirrors held next to the nevus in a "nevoscope." The digitized images are used in a computed tomography algorithm to calculate approximate vertical cross sections of the nevus. The algorithm is one we recently developed to permit reconstruction from a very few projections. Our method is completely noninvasive. It may be used to check all the nevi on a patient. Without excisions, we could establish a baseline three-dimensional shape for each nevus, follow any changes in time, and obtain an early warning of increase in thickness and possible malignancy.     

Proposal for Compact Optical Filters Using Large Index Step Binary Supergratings

Compact optical filters are proposed using an aperiodic grating of fixed element size [i.e., a binary supergrating (BSG)] with a large refractive index step. These filters allow for almost arbitrary wavelength filtering, yet they are more compact than previous demonstrations of BSG. The filters are designed using a combination of Boolean particle swarm optimization (B-PSO) and a one-dimensional transfer matrix method. To demonstrate the compact device size, several 50-mum-long single-wavelength transmission filters are demonstrated theoretically, each having a different wavelength while using the same structural parameters. A multiwavelength filter is also proposed in an 80-mum-long structure to show the versatility of the large refractive index step BSG. A genetic algorithm is substituted for the B-PSO; however, B-PSO shows better performance here. This work may be applied to produce compact optical filters for intrachip optical networks and compact tunable lasers, while using existing single-step photolithography processes.     

管理RoHS资源的策略

很不幸，我们在生活中经常会碰到这样的场景：在电子产品制造公司里，当人们第一次提出要贯彻从产品中消除有害物质的规定时，却无法说服管理层下决心拿出公司的资源来做这件事。相反，他们倒是听到了“这件事与我无关”的几个不同说法。     

Inside Vertical-Cavity Surface-Emitting Lasers: Extracting the Refractive Index From Spatial-Spectral Mode Images

We present a method to extract the internal effective refractive index of a vertical-cavity surface-emitting laser (VCSEL) from its transverse mode images. High spatial and spectral resolution mode images of an oxide-guided VCSEL were obtained using an etalon filter and an imaging spectrometer. The refractive index and the oxide radius were extracted from the field intensity distribution and the spectral wavelength of the laser modes. The procedure was repeated at two different currents and both gave a refractive index step of 0.046 plusmn 0.006 with a 14.1-mum oxide diameter. With several degrees of freedom for error available in the refractive index extraction, this method may be extended to ion-implanted, photonic crystal, and noncircular devices     

How to forge RSA key certificates

It is shown how certain types of key certificate suggested for preventing masquerade when using the RSA public key cryptosystem can be easily forged. A remedy is given, which is to use an alternative type of certificate, incorporating a one-way function.     

An Efficient Algorithm for Spectral Analysis of Heart Rate Variability

We present a simple efficient algorithm for the derivation of a heart rate signal from the electrocardiogram. We demonstrate that the amplitude spectrum of this heart rate signal more closely matches that of the input signal to an integral pulse frequency modulation (IPFM) model of the heart's pacemaker than do the spectra of other ECG-derived heart rate signals. The applicability of this algorithm in cross-spectral analysis between heart rate and other physiologic signals is also discussed.     

Corrosion of Fe-10Al-Cr alloys by coal char

Corrosion of iron-base alloys at 982°C (1800°F) by coal char is observed and the phase morphologies are discussed. No sulfidation was observed at 50 hr exposure. After 100 hr internal aluminum-rich sulfides were observed along with thick outer scales of iron oxide. The species causing the hightemperature-induced corrosion are probably sulfides and sulfates, present in most coal chars. Possible mechanisms for the corrosion are also discussed.Department of Materials Science and Mineral Engineering.     

Performance of Holstein and Swedish-Red × Jersey/Holstein crossbred dairy cows within low- and medium-concentrate grassland-based systems

This 2 × 2 factorial design experiment was conducted to compare the performance of spring-calving Holstein dairy cows (HOL, n = 34) with Swedish Red × Jersey/Holstein crossbred (SR × J/HOL, n = 34) dairy cows within low and medium concentrate input grassland-based dairy systems. The experiment commenced when cows calved and encompassed 1 full lactation. Cows were offered diets containing grass silage and concentrates [70:30 dry matter (DM) ratio, and 40:60 DM ratio, for low and medium, respectively] until turnout, grazed grass plus either 1.0 or 4.0 kg of concentrate/d during the grazing period (low and medium, respectively), and grass silage and concentrates (85:15 DM ratio, and 70:30 DM ratio, for low and medium, respectively) from rehousing and until drying off. No significant genotype × system interactions were present for any of the feed intake or full-lactation milk production data examined. Full-lactation concentrate DM intakes were 769 and 1,902 kg/cow for the low and medium systems, respectively, whereas HOL cows had a higher total DM intake than SR × J/HOL cows in early lactation, but not in late lactation. Although HOL cows had a higher lactation milk yield than SR × J/HOL cows, the latter produced milk with a higher fat and protein content, and thus fat plus protein yield was unaffected by genotype. Milk produced by the SR × J/HOL cows had a higher degree of saturation of fatty acids than milk produced by the HOL cows, and the somatic cell score of milk produced by the former was also higher. Throughout the lactation, HOL cows were on average 30 kg heavier than SR × J/HOL cows, whereas the SR × J/HOL cows had a higher body condition score than the HOL cows. Holstein cows had a higher incidence of mastitis and ovarian dysfunction that SR × J/HOL cows.