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81.
Using electric actuation and detection of oscillations in microcantilevers for pressure measurements
Gayatri Keskar Bevan Elliott Jay Gaillard Malcolm J. Skove Apparao M. Rao 《Sensors and actuators. A, Physical》2008,147(1):203-209
Response characteristics of a microcantilever, such as resonant frequency, amplitude, phase and quality factor, can be used for absolute pressure measurements in the range of 10−4 to 103 Torr. To this end, it would be very convenient to have the resonance of the microcantilever actuated and detected electrostatically. Herein, we report the nonlinear dynamics of microcantilevers under varying pressure and different gases using the harmonic detection of resonance (HDR) technique [J. Gaillard, M.J. Skove, R. Ciocan, A.M. Rao, Electrical detection of oscillations in 340 microcantilevers and nanocantilevers, Rev. Sci. Instrum. 77 (2006) 073907]. The HDR technique exploits nonlinearities in the cantilever-counter electrode system to allow electrostatic actuation and detection of the responses of the microcantilever to the pressure and gas composition. In particular, the 2nd and 3rd harmonics of the measured charge on the cantilever are investigated. The microcantilever demonstrates a quality factor of 10,000 at 10−3 Torr, and a usable response in the range from 10−3 to 103 Torr. The use of different harmonics can enable us to adjust the range of pressures over which the sensor has an efficacious response, enhancing its sensitivity to a particular environment. The experimental results are in reasonable agreement with theoretical calculations, despite the nonlinearities involved. 相似文献
82.
Ian Streeter Gregory G. Lidong Richard G. Compton 《Sensors and actuators. B, Chemical》2008,133(2):462-466
Cyclic voltammetry is recorded of the oxidation of ferrocyanide on a glassy carbon electrode modified with multiple layers of single-walled carbon nanotubes. The current response is interpreted in terms of semi-infinite planar diffusion towards the macro-electrode surface and in terms of oxidation of the electroactive species trapped in pockets in between the nanotubes. A thin layer model is used to illustrate the effects of diffusion within a porous layer. It is found that a semi-infinite planar diffusion model alone is not appropriate for interpreting the kinetics of the electron transfer at this electrode surface. In particular, caution should be exercised in respect of comparing voltammetric peak-to-peak potential separations between naked electrodes and nanotube-modified electrodes for the inference of electrocatalysis via electron transfer via the nanotubes. 相似文献
83.
Topology optimization of structures with integral compliant mechanisms for mid-frequency response 总被引:1,自引:1,他引:0
The purpose of this paper is to present a method for developing new truss-like sandwich structures that exhibit desirable
mid-frequency vibratory characteristics. Specifically, a genetic algorithm optimization routine is used to determine candidate
small scale structural topologies, i.e. unit cells, that may be used in the design of larger scale periodic sandwich structures.
This multi-scale procedure is demonstrated starting with several unit cell topology optimization examples. From these examples
a specific optimal unit cell is selected for further investigation and integration into a periodic sandwich beam. Computational
results indicate that the proposed optimization approach is effective when used to design new structures for reduced mid-frequency
vibratory response. 相似文献
84.
Jenkins RE Meng X Elliott VL Kitteringham NR Pirmohamed M Park BK 《Proteomics. Clinical applications》2009,3(6):720-729
Flucloxacillin is a synthetic penicillin used in the treatment of Staphylococcal infections. Adverse reactions to the drug are believed to arise through covalent modification of proteins, with tissue damage occurring secondary to an immune reaction. Serum proteins have been shown by adduct-specific antibodies to be modified by flucloxacillin, but the nature and sites of modification have not been characterised. Here, in vitro studies on HSA have shown by MS that the modification of protein lysine residues occurs in a dose-, time- and site-dependent manner. Affinity, cation exchange and reversed phase chromatography prior to MS revealed in vivo modification of HSA with flucloxacillin in tolerant patients, with up to nine modified lysine residues being detected in each patient, and with modification of Lys190 and Lys212 being detected in 8/8 patients. It was also revealed for the first time that plasma proteins could be modified with the 5-hydroxymethyl metabolite of flucloxacillin, and that essentially the same Lys residues were targeted by both the parent drug and its metabolite. This study provides a detailed characterisation of sites of chemical modification of an endogenous target and reveals candidate peptides for T-cell and antibody assays of flucloxacillin hypersensitivity. 相似文献
85.
Gregory N. Gol''tsman Ivan G. Goghidze Pavel B. Kouminov Boris S. Karasik Alexei D. Semenov Evgeni M. Gershenzon 《Journal of Superconductivity》1994,7(4):751-755
The transient voltage response in both epitaxial and granular YBaCuO thin films to 80 ps pulses of YAGNd laser radiation of wavelength 0.63 and 1.54 m was studied. In the normal and resistive states both types of films demonstrate two components: a nonequilibrium picosecond component and a bolometric nanosecond one. The normalized amplitudes are almost the same for all films. In the superconducting state we observed a kinetic inductive response and two-component shape after integration. The normalized amplitude of the response in granular films is up to five orders of magnitude larger than in epitaxial films. We interpret the nonequilibrium response in terms of a suppression of the order parameter by the excess of quasiparticles followed by the change of resistance in the normal and resistive states or kinetic inductance in the superconducting state. The sharp rise of inductive response in granular films is explained both by a diminishing of the cross section for current percolation through the disordered network of Josephson weak links and by a decrease of condensate density in neighboring regions. 相似文献
86.
Gregory NG 《Meat science》1994,36(1-2):45-56
This paper reviews some of the recent developments in scientific research into preslaughter handling, transport, stunning and slaughter. Particular emphasis has been placed on work published within the past 2 years, and on the welfare and meat quality aspects of the subject. 相似文献
87.
The role of the vertebral arteries in delaying loss of sensibility following neck sticking in slaughter calves was investigated. Vertebral artery blood flow was measured using probes before, during and after electrical stunning and slaughter. Systemic blood pressure, electrocorticogram, visually evoked responses and the occurrence of carotid occlusions were also recorded. When carotid occlusion occurred, the time to onset of brain failure was delayed based on the development of an isoelectric state. In addition, when carotid occlusion occurred the mean arterial blood pressure was sustained for longer following slaughter, and concurrently vertebral artery blood flow could be maintained at about 30% of its initial level for up to 3 min. In some animals vertebral artery flow increased substantially following sticking. When chest sticking was used no occlusion of vessels occurred, mean arterial blood pressure fell promptly (within 8 s) and the onset of an isoelectric state did not extend beyond one minute. In addition, visually evoked responses were not present after 5 s following chest sticking. 相似文献
88.
Yong Ryun Kim Oskar J. Sandberg Stefan Zeiske Gregory Burwell Drew B. Riley Paul Meredith Ardalan Armin 《Advanced functional materials》2023,33(16):2300147
Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has been one of the most established hole transport layers (HTL) in organic solar cells (OSCs) for several decades. However, the presence of PSS− ions is known to deteriorate device performance via a number of mechanisms including diffusion to the HTL-active layer interface and unwanted local chemical reactions. In this study, it is shown that PSS− ions can also result in local p-doping in the high efficiency donor:non-fullerene acceptor blends – resulting in photocurrent loss. To address these issues, a facile and effective approach is reported to improve the OSC performance through a two-component hole transport layer (HTL) consisting of a self-assembled monolayer of 2PACz ([2-(9H-Carbazol-9-yl)ethyl]phosphonic acid) and PEDOT:PSS. The power conversion efficiency (PCE) of 17.1% using devices with PEDOT:PSS HTL improved to 17.7% when the PEDOT:PSS/2PACz two-component HTL is used. The improved performance is attributed to the overlaid 2PACz layer preventing the formation of an intermixed p-doped PSS− ion rich region (≈5–10 nm) at the bulk heterojunction-HTL contact interface, resulting in decreased recombination losses and improved stability. Moreover, the 2PACz monolayer is also found to reduce electrical shunts that ultimately yield improved performance in large area devices with PCE enhanced from 12.3% to 13.3% in 1 cm2 cells. 相似文献
89.
Qi Li Guizhen Liu Bofeng Cai Gregory Leamon Lan-Cui Liu Zheng-Ao Chen Xiaochun Li 《Clean Technologies and Environmental Policy》2017,19(8):2041-2056
Carbon dioxide capture, utilization and storage (CCUS) is regarded as an important carbon emissions reduction technology response to climate change. Though some full-chain CCUS pilot projects have operated in China, many barriers exist when stepping up to commercial applications, including significant negative perceptions of the environmental risk of CCUS. Therefore, to tailor constructive training or outreach programs for public acceptance of CCUS in China, a large national survey of public perceptions of CCUS technology was conducted in 2013. The questionnaire contained four themes focusing on people with a tertiary education. Six hundred paper–pencil questionnaires were dispatched to 22 universities/enterprises across 19 provinces and 2 municipalities, with a response rate of 95%. The results show that 91.4% of the participants agreed that the earth was experiencing climate change, and 74.3% were interested in low-carbon technologies, but while 22% had heard of CCUS, although with limited knowledge, only 3.6% had a good understanding of the technology. The results from the second part of the questionnaire show that 80.4% of participants believed that CCUS may help to mitigate the impacts of global warming, but the “Not in My Back Yard” (NIMBY) phenomenon was obvious from the location-based objections to transportation and storage processes. In addition, ten listed CCUS environmental management policies received extensive recognition from the participants, and about half of the participants considered that the related government departments should be responsible for environmental management as a first priority. The survey also indicates that the most trusted sources through which the survey participants obtain CCUS information are academic journals and textbooks, television, radio and newspapers, expert lectures and brochures on CCUS demonstration projects. According to the survey of public awareness of the environmental impact and management of CCUS technology in China, CCUS technology rates well for environmental benefits, but high environmental risk perceptions of CCUS lead to a lower acceptance of this carbon emissions reduction technology. 相似文献
90.
Gemma M. Paech Sarah M. Jay Nicole Lamond Gregory D. Roach Sally A. Ferguson 《Applied ergonomics》2010,41(4):600-606
Shiftwork involving early morning starts and night work can affect both sleep and fatigue. This study aimed to assess the impact of different rostering schedules at an Australian mine site on sleep and subjective sleep quality. Participants worked one of four rosters;
- 4 × 4 (n = 14) 4D4O4N4O
- 7 × 4 (n = 10) 7D4O7N40
- 10 × 5 (n = 17) 5D5N50
- 14 × 7 (n = 12) 7D7N70