TagSNP selection, which aims to select a small subset of informative single nucleotide polymorphisms (SNPs) to represent the
whole large SNP set, has played an important role in current genomic research. Not only can this cut down the cost of genotyping
by filtering a large number of redundant SNPs, but also it can accelerate the study of genome-wide disease association. In
this paper, we propose a new hybrid method called CMDStagger that combines the ideas of the clustering and the graph algorithm,
to find the minimum set of tagSNPs. The proposed algorithm uses the information of the linkage disequilibrium association
and the haplotype diversity to reduce the information loss in tagSNP selection, and has no limit of block partition. The approach
is tested on eight benchmark datasets from Hapmap and chromosome 5q31. Experimental results show that the algorithm in this
paper can reduce the selection time and obtain less tagSNPs with high prediction accuracy. It indicates that this method has
better performance than previous ones. 相似文献
Control of frictional forces is required in many applications of tribology. While the problem is approached by chemical means traditionally, a recent approach was proposed to control the system mechanically to tune frictional responses. We design feedback control laws for a one-dimensional particle array sliding on a surface subject to friction. The Frenkel-Kontorova model describing the dynamics is a nonlinear interconnected system and the accessible control elements are average quantities only. We prove local stability of equilibrium points of the un-controlled system in the presence of linear and nonlinear particle interactions, respectively. We then formulate a tracking control problem, whose control objective is for the average system to reach a designated targeted velocity using accessible elements. Sufficient stabilization conditions are explicitly derived for the closed-loop error systems using the Lyapunov theory based methods. Simulation results show satisfactory performances. The results can be applied to other physical systems whose dynamics is described by the Frenkel-Kontorova model. 相似文献
Intravenous infusion of mice with viable allogeneic lymphocytes can produce donor-specific enhancement of skin graft survival, but only if the injected lymphocytes can persist in the host's recirculating lymphocyte pool for at least 3 days. We have investigated the relative roles of class I and class II MHC for C57BL/6 mice infused with lymphoid cells from co-isogenic strains mutated at class I MHC (bm1) or class II MHC (bm12), and for A.TH lymphoid cells infused into C3H (class I different, class II identical) or A.TH (class II different, class I identical). Injected cells differing from the host at class I MHC, but not at class II MHC, can be rapidly removed by host natural immune mechanisms (probably NK cells). Persistence is favored if the injected cells also carry host class I MHC, i.e., tolerance is more readily induced by injecting F1 (A x B) into A rather than B into A, consistent with the "missing self" hypothesis of NK recognition, with class I MHC being the relevant self-marker. Injected cells differing from the host at class II MHC but not at class I MHC always persist for at least 3 days, even when class I-different cells are being actively removed. 相似文献
The Journal of Supercomputing - We argue the agent’s low generalization problem for searching target object in challenging visual navigation could be solved by "how" and... 相似文献
The Journal of Supercomputing - In the literature, most previous studies on English implicit inter-sentence relation recognition only focused on semantic interactions, which could not exploit the... 相似文献
International Journal of Computer Vision - Visual tracking of generic objects is one of the fundamental but challenging problems in computer vision. Here, we propose a novel fully convolutional... 相似文献
The heavy reliance on data is one of the major reasons that currently limit the development of deep learning. Data quality directly dominates the effect of deep learning models, and the long-tailed distribution is one of the factors affecting data quality. The long-tailed phenomenon is prevalent due to the prevalence of power law in nature. In this case, the performance of deep learning models is often dominated by the head classes while the learning of the tail classes is severely underdeveloped. In order to learn adequately for all classes, many researchers have studied and preliminarily addressed the long-tailed problem. In this survey, we focus on the problems caused by long-tailed data distribution, sort out the representative long-tailed visual recognition datasets and summarize some mainstream long-tailed studies. Specifically, we summarize these studies into ten categories from the perspective of representation learning, and outline the highlights and limitations of each category. Besides, we have studied four quantitative metrics for evaluating the imbalance, and suggest using the Gini coefficient to evaluate the long-tailedness of a dataset. Based on the Gini coefficient, we quantitatively study 20 widely-used and large-scale visual datasets proposed in the last decade, and find that the long-tailed phenomenon is widespread and has not been fully studied. Finally, we provide several future directions for the development of long-tailed learning to provide more ideas for readers.
Applied Intelligence - In recent years, person re-identification (re-ID) has become a widespread research topic that focuses on retrieving target pedestrians from a set of images, typically taken... 相似文献