Erbium-doped fiber amplifier for video distribution networks

The possibility of an application of Er-doped fiber amplifiers to AM-FDM (frequency division multiplexing) or FM-FDM video distribution networks is discussed. The measured noise and modulation distortion properties of ER-doped fiber amplifiers are good enough to meet even the severe quality standards set for trunk lines. A carrier-to-noise ratio (CNR) of 57 dB for an AM-FDM transmission was measured. A second-order harmonic distortion (HD2) of less than -56 dB was measured by the monotone method (modulation depth m=50%), and a cross modulation distortion (XM) of less than -63 dB was measured by the two-tone method (m=25%×channel). On the basis of these values, composite second-order distortion (CSO) and XM in a 40-channel transmission were estimated as less than -57 dB and -73 dB, respectively. Significant reduction of noise and modulation distortion is made possible by optimizing the length of Er-doped fiber amplifiers and using input- and output-port isolators     

Modified thermoelectric figure of merit estimated from enhanced mobility of [100] oriented beta-FeSi<Subscript>2</Subscript> thin film

The modification of thermoelectric figure of merit was estimated from enhanced mobility of [100] oriented beta-FeSi₂ film. beta-FeSi₂ on Si(001) substrate was prepared by molecular beam epitaxy method using an Fe source. The crystallographic orientation of beta-FeSi₂ film on Si(001) substrate was characterized by using X-ray diffraction. Using scanning electron microscopy, surface morphology and film thickness of samples were observed and estimated, respectively. The mobility of beta-FeS₂ film on Si(001) substrate were also characterized by Hall measurement at room temperature. A part of the enhancement of figure of merit was evaluated as the functions of mobility and crystallographic orientation of samples.     

Oxygen Diffusion in Single- and Poly-Crystalline Zinc Oxides

¹⁸O diffusion coefficients were measured in zinc oxide ceramics using a secondary ion mass spectrometer. The results are interpreted as indicating extrinsic behavior. The values of the lattice diffusion coefficients with higher valence dopants compared with zinc ions are greater than lower valence dopant such as lithium ions. Using the data at deeper depth, the grain boundary diffusivity of oxide ions was also evaluated. Although the lattice diffusion coefficients varied by two orders of magnitude, the products of grain boundary width and grain boundary diffusion coefficient were less sensitive to the type of dopants.     

Reconstruction of lake-level and climate changes in Lake Qarun,Egypt, during the last 7000 years

Sediment cores from Lake Qarun provide a record of mid-late Holocene climatic changes in Northern and Eastern Africa as well as environmental changes due to the activities of ancient Egyptians. We used sedimentological, mineralogical, and geochemical analyses of the cores to investigate long-term variations in lake level due to changing hydrologic inputs. An age model based on three paired ¹⁴C and paleomagnetic measurements suggests that the base of the sediment cores is as old as ∼ 5000 B.C.E. Geochemical analyses indicated that lake sediments were derived from Nile floods with an admixture of Saharan sand. Laminated endogenic carbonate-rich clayey silt lithofacies with benthic diatoms are indicative of relatively low lake levels, saline waters and dry conditions; massive lithofacies with planktonic diatom species are indicative of relatively high lake levels, fresh waters and humid conditions. Faintly laminated clayey silt lithofacies suggest intermediate conditions. Variations in lithology as well as diatom composition suggest that the lake level has varied from relatively high levels in its early history to lower levels in later years although there have been numerous cycles in water level over the past 7000 years. A combination of climate changes in the source area of the Nile River as a result of monsoon dynamics; climatic changes in the setting area of the Lake Qarun; and human activities through the dynasties in Egypt produced these variations in lake level.     

Bibliometric Distance between Methodology and Application in Statistics

This paper analyses communications between statistical methodology and applied statistics in terms of the similarity and dissimilarity in their authorship and citation patterns, and further the communication distance between them in terms of mutual citation and the time lag therein. Hypotheses are presented on their difference and distance and are verified for data from the Journal of the Royal Statistical Society, the oldest statistical society in the world. The data analysis reveals that they are indeed different and distant each other to a certain extent but less distinctly than initially conjectured in the hypotheses.     

Liposome‐Based in Vitro Evolution of Aminoacyl‐tRNA Synthetase for Enhanced Pyrrolysine Derivative Incorporation

Methanosarcina species pyrrolysyl‐tRNA synthetase (PylRS) attaches Pyl to its cognate amber suppressor tRNA. The introduction of two mutations (Y384F and Y306A) into PylRS was previously shown to generate a mutant, designated LysZ‐RS, that was able to attach N‐benzyloxycarbonyl‐L ‐lysine (LysZ) to its cognate tRNA. Despite the potential of LysZ derivatives, further LysZ‐RS engineering has not been performed; consequently, we aimed to generate LysZ‐RS mutants with improved LysZ incorporation activity through in vitro directed evolution. Using a liposome‐based in vitro compartmentalization (IVC) approach, we screened a randomly mutagenized gene library of LysZ‐RS and obtained a mutant that showed increased LysZ incorporation activity both in vitro and in vivo. The ease and high flexibility of liposome‐based IVC should enable the evolution of not only LysZ‐RS that can attach various LysZ derivatives but also of other enzymes involved in protein translation.     

Estimating the burden of acute gastroenteritis and foodborne illness caused by Campylobacter, Salmonella, and Vibrio parahaemolyticus by using population-based telephone survey data, Miyagi Prefecture, Japan, 2005 to 2006

Most cases of acute gastroenteritis and foodborne disease are not ascertained by public health surveillance because the ill person does not always seek medical care and submit a stool sample for testing, and the laboratory does not always test for or identify the causative organism. We estimated the total burden of acute gastroenteritis in Miyagi Prefecture, Japan, using data from two 2-week cross-sectional, population-based telephone surveys conducted in 2006 and 2007. To estimate the number of acute gastroenteritis illnesses caused by Campylobacter, Salmonella, and Vibrio parahaemolyticus in Miyagi Prefecture, we determined the number of cases for each pathogen from active laboratory-based surveillance during 2005 to 2006 and adjusted for seeking of medical care and submission of stool specimens by using data from the population-based telephone surveys. Monte Carlo simulation was used to incorporate uncertainty. The prevalence of acute gastroenteritis in the preceding 4 weeks was 3.3% (70 of 2,126) and 3.5% (74 of 2,121) in the winter and summer months, yielding an estimated 44,200 episodes of acute gastroenteritis each year in this region. Among people with acute gastroenteritis, the physician consultation rate was 32.0%, and 10.9% of persons who sought care submitted a stool sample. The estimated numbers of Campylobacter-, Salmonella-, and V. parahaemolyticus -associated episodes of acute gastroenteritis were 1,512, 209, and 100 per 100,000 population per year, respectively, in this region. These estimates are significantly higher than the number of reported cases in surveillance in this region. Cases ascertained from active surveillance were also underrepresented in the present passive surveillance, suggesting that complementary surveillance systems, such as laboratory-based active surveillance in sentinel sites, are needed to monitor food safety in Japan.