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91.
Narisawa N Furukawa S Kawarai T Ohishi K Kanda S Kimijima K Negishi S Ogihara H Yamasaki M 《International journal of food microbiology》2008,124(1):103-107
We investigated the effects of skimmed milk and its protein fractions (casein, whey, globulin, and albumin) on the injury and inactivation of Escherichia coli K-12 by high hydrostatic pressure (HHP) treatment. The protective effect of skimmed milk on HHP-mediated inactivation and injury of E. coli increased with increases in the skimmed milk concentration. However, protein fractions derived from skimmed milk did not exhibit this protective effect. Microscopy analysis by DAPI/PI staining indicated that some cells were localized in the solid portion of skimmed milk, and some of these cells were alive. The coagulated fraction derived from the autoclaved whey fraction also showed a significant protective effect. We speculate that the solid portion in skimmed milk could provide the protective effect to bacterial cells. 相似文献
92.
Jun Suzurikawa Masayuki Nakao Hirokazu Takahashi 《IEEJ Transactions on Electrical and Electronic Engineering》2011,6(4):392-393
Here, we describe a novel method for surface passivation of the thin‐film light addressable potentiometric sensor (LAPS). To form a uniform passivation layer, perhydropolysilazane (PHPS) was utilized as a spin‐coatable precursor of silica. After transformation of PHPS into silica by baking, we introduced an O2 plasma treatment aiming for enhancement of the water resistance of the PHPS‐derived silica (PDS) film by completing the PHPS‐to‐silica conversion. To confirm the effect of the O2 plasma treatment, the PDS film was deposited on a thin‐film LAPS electrode and tested by immersion in a cell culturing medium. The immersion test demonstrated that the plasma‐treated PDS film could keep the electrode stable longer than the untreated could. With the treated PSD film of 600 nm in thickness, a lifetime of the thin‐film LAPS was estimated at over 2 weeks, which is sufficient for cell culturing experiments. © 2011 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. 相似文献
93.
94.
Dr. Takuya Kobayakawa Kento Ebihara Yuzuna Honda Dr. Masayuki Fujino Dr. Wataru Nomura Prof. Naoki Yamamoto Dr. Tsutomu Murakami Prof. Hirokazu Tamamura 《Chembiochem : a European journal of chemical biology》2019,20(16):2101-2108
C34, a 34-mer fragment peptide, is contained in the HIV-1 envelope protein gp41. A dimeric derivative of C34 linked through a disulfide bridge at its C terminus was synthesized and found to display potent anti-HIV activity, comparable with that of a previously reported PEGylated dimer of C34REG. The reduction in the size of the linker moiety for dimerization was thus successful, and this result might shed some light on the mechanism of the suppression of six-helix bundle formation by these C34 dimeric derivatives. Addition of a Gly-Cys(CH2CONH2)-Gly-Gly motif at the N-terminal position of a C34 monomeric derivative significantly increased the anti-HIV-1 activity. This moiety functions as a new pharmacophore, and this might provide a useful insight into the design of potent HIV-1 fusion inhibitors. 相似文献
95.
Hirokazu Kojima Tomoki Matsuda Kazuki Kano Taku Tsujimura 《International Journal of Hydrogen Energy》2021,46(14):9433-9442
Energy storage using liquid organic hydrogen carrier (LOHC) is a long-term method to store renewable energy with high hydrogen energy density. This study investigated a simple and low-cost system to produce methylcyclohexane (MCH) from toluene and hydrogen using fluctuating electric power, and developed its control method. In the current system, hydrogen generated by an alkaline water electrolyzer was directly supplied to hydrogenation reactors, where hydrogen purification equipment such as PSA and TSA is not installed to decrease costs. Hydrogen buffer tanks and compressors are not equipped. In order to enable MCH production using fluctuating electricity, a feed-forward toluene supply control method was developed and introduced to the system. The electrolyzer was operated under triangular waves and power generation patterns of photovoltaic cells and produced hydrogen with fluctuating flow rates up to 7.5 Nm3/h. Consequently, relatively high purity of MCH (more than 90% of MCH mole fraction) was successfully produced. Therefore, the simplified system has enough potential to produce MCH using fluctuating renewable electricity. 相似文献
96.
Kyoko Hori Masahiro Fukuta Hirokazu Shimooka Shigemi Kohiki Toetsu Shishido Masaoki Oku Masanori Mitome Yoshio Bando 《Journal of Alloys and Compounds》2005,390(1-2):261-264
β-Ga2O3 nanocolumns straightened and crossed perpendicularly each other were deposited on MgO (1 0 0) substrate by vapor phase transport method. Growth of the nanocolumns was examined at steps of 1000, 1050, and 1200 °C in elevation of source-boat temperature. We have drawn out the substrate from deposition-tube at each source-boat temperatures of 1000, 1050, and 1200 °C. Scanning electron microscopy of the sample with source-boat temperature of 1200 °C demonstrated that the straightened and elongated nanocolumns are crossing perpendicularly each other. Typical lengths of the nanocolumns were in the range of several hundreds nanometers below 1050 °C, and those of 1200 °C were in the range of ten to fifteen hundreds nanometers. Diameters of the nanocolumns stayed in the range of few hundreds nanometers, notwithstanding variation of the source temperature. X-ray diffraction and transmission electron microscopy with energy dispersive X-ray spectroscopy revealed that the nanocolumns are monoclinic β-Ga2O3 crystal, and the (4 0 0) plane of β-Ga2O3 nanocolumns is parallel to the (1 0 0) plane of MgO substrate. 相似文献
97.
Mitsuhiro Hibino Hirokazu Kawaoka Haoshen Zhou Itaru Honma 《Electrochimica acta》2004,49(28):5209-5216
Hydrated sodium manganese oxide was synthesized by reducing permanganate ion using ethanol by a sol–gel method. By including acetylene black in the synthetic reaction, we obtained composite materials in which sodium manganese oxide hydrate particles were small and mixed well with the acetylene black. We evaluated those composites as a lithium battery cathode and found that they showed 170 mA h g−1 under 5 mA g−1 and 117 mA h g−1 under 5 A g−1 on the basis of composite weight. This rapid discharge performance was probably caused by the favorable contact condition of the composite constituents. 相似文献
98.
Masaki Kaji Michael E. Stevenson Richard C. Bradt 《Journal of the American Ceramic Society》2002,85(2):415-422
The Knoop microhardness anisotropy profile was determined for the basal plane of a Czochralski grown alumina single crystal for indentation test loads from 100 through 1000 g. Microhardness maxima occur at low indentation test loads for the long axis of the Knoop indenter parallel to the 〈2[Onemacr][Onemacr]0〉. Minima exist for the long axis parallel to the 〈10[Onemacr]0〉. This low indentation test load profile is attributed to slip on the primary slip system, the (0001)〈[Onemacr][Onemacr]20〉, as previously noted by Brookes and co-workers. The degree of the microhardness anisotropy decreases for higher indentation test loads. This results from the activation of multiple slip systems to accommodate the greater amounts of plastic flow required by the larger indentation sizes. The microhardness profile becomes more uniform with increasing indentation test load until the Knoop microhardness approaches a test-load-independent, orientation-independent microhardness of 1167 ± 34 kg/mm2 . The indentation size effect (ISE) was further investigated through lubricated indentation hardness measurements. Lubrication of the test specimen surface significantly reduces the ISE. Results indicate that friction between the test specimen surface and the indenter facets is a major portion of the ISE. 相似文献
99.
Lian Gao Qiang Li Weiling Luan Hirokazu Kawaoka Tohru Sekino Koichi Niihara 《Journal of the American Ceramic Society》2002,85(4):1016-1018
This communication reports on the preparation and electric properties of dense nanocrystalline ZnO ceramics. By spark plasma sintering, nanocrystalline (∼100 nm) ZnO ceramics with a high density of 98.5% were obtained at a very low temperature of 550°C. Electric property measurement revealed a novel conduction nonlinearity in the sample sintered at 500°C. This phenomenon is due to the nanometerization of ZnO crystal and the grain boundary layer with an amorphous interfacial layer. 相似文献
100.
Hirokazu Chazono Tomoya Hagiwara 《International Journal of Applied Ceramic Technology》2005,2(1):45-50
Structure–property relationship in BaTiO3 (BT)-based dielectrics for multi-layer ceramic capacitors with nickel internal electrode was investigated using samples having various HoO3/2 concentrations by measuring temperature characteristics of capacitance, voltage–current characteristics, lifetime at highly accelerated life test, high-resolution analytical electron microscope, and frequency response at elevated temperature and ultra-low frequency. It was concluded that the addition of Ho affected the shell and grain boundary (GB) characteristics. Incorporation of Ho into BT perovskite lattice and the change in GB characteristics along with the doped concentration of HoO3/2 were discussed to better understand the role of doped Ho2 O3 . 相似文献