An On-Chip Multichannel Waveform Monitor for Diagnosis of Systems-on-a-Chip Integration

An on-chip multichannel waveform monitoring technique enhances built-in test and diagnostic capabilities of systems- on-a-chip (SoC) integration. The proposed multichannel monitor includes multiple probing front-end modules and a single shared waveform acquisition kernel that consists of an incremental variable step delay generator and an incremental reference voltage generator, featuring adaptive sample time generation for the operation of a target circuit and unidirectional waveform acquisition flow for area-efficient control. A 16-channel prototype in 0.18-mum CMOS technology demonstrated on-chip waveform acquisition at 40-ps and 200-muV resolutions. Combined on- and off-chip streamed-bit processing achieves background continuous waveform acquisition at 260 ms per single timing point for repetitive signals, while eliminating the integration of on-die high-capacity memory. A 700 mum times 600 mum area was occupied by a waveform acquisition kernel and an additional 60 mum times 100 mum area for each front-end module. The developed on-chip multichannel waveform monitoring technique is waveform accurate, area efficient, and suitable for diagnosis toward power supply and signal integrity in analog and digital circuits in mixed-signal SoC integration.     

Effects of bile acid feeding on hepatic deoxycholate 7α-hydroxylase activity in the hamster

In order to investigate the effects of bile acid feeding on hepatic microsomal deoxycholate 7α-hydroxylase activity, three different bile acids were administered (0.2% w/w in chow) to hamsters for two weeks. Deoxycholate 7α-hydroxylase activity was increased markedly by feeding of cholic acid (CA) and slightly by deoxycholic acid (DCA) Chenodeoxycholic acid (CDCA) had little effect on the enzyme activity. Feeding each of the bile acids significantly inhibited the activity of cholesterol 7α-hydroxylase in the order CDCA≥ DCA>CA. There was no correlation between deoxycholate 7α-hydroxylase activity and cholesterol 7α-hydroxylase activity. It is concluded that the activity of deoxycholate 7α-hydroxylase is up-regulated by feeding DCA and CA and that the mechanism seems to be different from that of cholesterol 7α-hydroxylase. The increased activity of hepatic deoxycholate 7α-hydroxylase by CA and DCA should be beneficial in minimizing the toxic effects of DCA in the hamster.     

Oxygen-permselectivity in new type polyorganosiloxanes with carboxyl group on the side chain

Summary Oxygen-permselectivity through polyorganosiloxanes with carboxyl group on the side chain is discussed in terms of the differences between the O₂, N₂ diffusion coefficients or their solubility coefficients. The oxygen-selectivity increases from 2 to 5 with the increase in the carboxyl component of the side chain. Especially the selectivity in the diffusion coefficient is found to more contribute to the oxygenpermselectivity in comparison with that of the solubility coefficient. But the permeation coefficient decreases with the permselectivity.This work was partially supported by a Grand-in-Aid from the Ministry of Education, Science and Culture, Japan.     

Context-Based Network and Application Management on Seamless Networking Platform

A context-based adaptive communication system is introduced for use in heterogeneous networks. Context includes the user's presence, location, available network interfaces, network availability, network priority, communication status, terminal features, and installed applications. An experimental system was developed to clarify the feasibility of using context information to flexibly control networks and applications. The system operates on a seamless networking platform we developed for heterogeneous networks. By using contexts, the system can inform the caller and callee of applications they can access, which are available through the network before communication occurs. Changes in contexts can switch an on-going application to another during actual communication. These functions provide unprecedented styles of communication. A business scenario for a seamless networking provider is also presented. Dr. Morikawa has also been in charge of NICT's Mobile Networking Group. Masugi Inoue received his B.E. from Kyoto University in 1992 and his M.E. and D.E. from the University of Tokyo in 1994 and 1997, all in the field of Electrical Engineering. He is currently a senior researcher at the Yokosuka Radio Communications Research Center under the National Institute of Information and Communications Technology (NICT), Japan, and has been engaged in R&D on ultrahigh-speed WLANs and mobile networking. He joined the Communications Research Laboratory (CRL) of the Ministry of Posts and Telecommunications, Japan, in 1997, which was reorganized as NICT in April 2004. He was a visiting researcher at Polytechnic University in Brooklyn, New York in 2000. Khaled Mahmud received his B.Sc. (Eng.) in Electrical and Electronics Engineering from the Bangladesh University of Engineering and Technology in Dhaka in 1991. He received his M.E. and Ph.D. in the same field from Shizuoka University in Japan, in 1997 and 2000, respectively. He was a research fellow at NICT, Japan, from 2000 to 2004. He is currently an Assistant Professor in the Department of Computer Science and Engineering at North South University, Bangladesh. His research interests include modulation-demodulation techniques, software radio, mobile communication systems, wireless Internet, and IP mobility technologies. Homare Murakami received his B.E. and M.E. in Electronic Engineering from Hokkaido University in 1997 and 1999. In 2004, he received the Young Investigators Award from IEICE. He is currently a researcher at NICT's Mobile Networking Group. He is also an industrial PhD student in Aalborg University since 2003. His interest areas are naming scheme, wireless TCP and new transport protocol, IP mobility, fast handover method, and location management. Mikio Hasegawa received his B. Eng, M. Eng., and Dr. Eng. in 1995, 1997, and 2000 from Science University of Tokyo. From 1997 to 2000, he was a Research Fellow of the Japan Society for the Promotion of Science (JSPS). He is currently a senior researcher in Mobile Networking Group, National Institute of Information and Communications Technology, and a technical advisor in ChaosWare Inc. His research interests include applications of chaotic dynamical theory, combinatorial optimization, mobile networks, and ubiquitous computing. Hiroyuki Morikawa received his B.E., M.E., and D.E. in Electrical Engineering from the University of Tokyo in 1987, 1989, and 1992. He is currently an Associate Professor in the Department of Frontier Informatics at the University of Tokyo and is in charge of NICT's Mobile Networking Group. His research interests are in the areas of computer networks, mobile computing/networks, ubiquitous computing, and network services. He serves as Editor of Transactions of the IEICE and has been on the technical program committees of IEEE/ACM conferences and workshops. He sits on numerous telecommunications advisory committees and frequently serves as a consultant to the government.     

The terminal protein of the linear DNA plasmid pGKL2 shares an N-terminal domain of the plasmid-encoded DNA polymerase

The 36K protein attached at the 5′ end of the linear DNA plasmid pGKL2 from the yeast Kluyveromyces lactis was first purified and characterized. The terminal protein was purified from cells (1 kg wet weight) by ammonium sulphate precipitation and two rounds of centrifugation to equilibrium in CsCl gradients. The pGKL2 was present only in the post-microsomal supernatant. Approximately 10 mg of the purified pGKL2 was recovered and digested with DNase I. The terminal protein (final ca. 0·8 mg) was homogeneous by electrophoresis and we determined the N-terminal amino acid sequence up to ten residues, showing that it existed in the cryptic N-terminal domain of pGKL2-ORF2 (DNA polymerase) sequence.     

Observation of iron silicide formation by plan-view transmission electron microscopy

The formation and the phase transitions of iron silicide by solid-phase epitaxy have been investigated by means of plan-view transmission electron microscopy, which enables us to observe a clean interface between Fe and Si. Layers of Fe were deposited on Si (100) at room temperature in an ultrahigh vacuum chamber. The sample was annealed in the electron microscope at a temperature between 673 and 1073 K. After annealing at 673 K, FeSi crystallites were formed with various orientations. When the annealing temperature was increased to 973 K, we found that the crystallites suddenly started to coalesce into grains of several hundreds of nanometers in size and polycrystalline beta-FeSi2 was formed. These phase transitions were also confirmed with electron energy-loss spectroscopy.     

Phase and magnetic properties of iron oxide clusters in 20CaO·20SiO2·7Fe2O3·6FeO glasses

The annealing of 20CaO·20SiO₂·7Fe₂O₃·6FeO glasses at 973K in vacuo produced clusters of iron oxide, the shape of which was nearly spherical and the diameter distributed in the narrow range 25–115Å. The phase of clusters was identified to be Fe³⁺(Fe³⁺ _{poststagger|1.30}Fe²⁺ _{poststagger|0.55}V_0.15)·O₄ in the inverse spinel structure based upon the Mössbauer spectra and x-ray diffraction profiles. The clusters exhibited superparamagnetism and their effective anisotropy energy constant was inversely proportional to the cluster diameter. The magnetization of the glasses measured by a vibrating sample magnetometer was 7.2 × 10^-6 Wbmkg^-1 at 10 kOe at room temperature and smaller than the value calculated assuming that the whole clusters have superparamagnetism. These results suggest the pinning of spins near the cluster surface.     

Encoding of information into neural spike trains in an auditory nerve fiber model with electric stimuli in the presence of a pseudospontaneous activity

This paper presents an information-theoretic analysis of neural spike trains in an auditory nerve fiber (ANF) model stimulated extracellularly with Gaussian or sinusoidal waveforms in the presence of a pseudospontaneous activity of spike firings. In the computer simulation, stimulus current waveforms were applied repeatedly to a stimulating electrode located 1 mm above the 26th node of Ranvier, in an ANF axon model having 50 nodes of Ranvier, each consisting of stochastic sodium and potassium channels. From spike firing times recorded at the 36th node of Ranvier, a post-stimulus time histogram (PSTH) was generated, and raster plots were depicted for 30 stimulus presentations, in order to investigate the temporal precision and reliability of the spike firing times. Also, inter spike intervals were generated and then "total" and "noise" entropies were estimated to obtain the mutual information and the information rate of the spike trains. It was shown in the case of Gaussian electric stimuli that the temporal precision of spike firing times and the reliability of spike firings were found to increase as the standard deviation (SD) of the Gaussian electric stimuli increased. It was also shown in the case of sinusoidal electric stimuli where there was a specific amplitude of sinusoidal waveforms, the information rate being maximized. It was implied that setting the parameters of electric stimuli to the specific values which maximize the information rate might contribute to efficiently encoding information into the spike trains in the presence of a pseudospontaneous activity of spike firings.     

Bias point thermal shift growth in Z-cut LiNbO/sub 3/ Modulators

Growth of a bias point thermal shift induced by dc bias in z-cut LiNbO/sub 3/ optical intensity modulators is quantitatively discussed from the standpoint of its impact on field service. During 20 years of device operation under a worst-case dc bias condition, the thermal shift slope grows almost symmetrically with respect to a bias polarity. An initial small thermal shift of around /spl plusmn/7 mV//spl deg/C (3/spl sigma/ distribution bounds) increases continuously over time with biased operation at 55/spl deg/C and approaches /spl plusmn/70 mV//spl deg/C after 20 years. This increased temperature sensitivity would generate approximately a 2-V bias point shift toward the bias rail when modulator is exposed to temperature variation from 55/spl deg/C to 25/spl deg/C.