Predicting remaining useful life (RUL) is crucial for system maintenance. Condition monitoring makes not only degradation data available for RUL estimation but also categorized health status data for health state identification. However, RUL prediction has been treated as an independent process in most cases even though potential relevance exists with health status detection process. In this paper, we propose a convolution neural network based multi-task learning method to reflect the relatedness of RUL estimation with health status detection process. The proposed method applied to the C-MAPSS dataset for aero-engine unit prognostics supported superior performances to existing baseline models.
Synergistic effects of organically modified montmorillonite (OMMT) in combination with different metal oxides (Bi2O3, Sb2O3, and MoO3) on the fire safety enhancement of the intumescent flame-retarded epoxy resins (EPs) were systematically evaluated. The results from X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses show that the OMMT and metal oxides acquire a uniform distribution in the EP matrix, and OMMT platelets exhibit a fully exfoliated state. The flammability and thermogravimetry (TG) tests show that the intumescent flame retardant (IFR)-OMMT-metal oxide ternary system can endow EPs with the higher synergistic efficiencies on the enhancement of flame retardancy, smoke suppression properties, and charring ability compared to those of IFR or IFR-OMMT system, and the synergistic efficiency is the following order: IFR/OMMT/Sb2O3 > IFR/OMMT/MoO3 > IFR/OMMT/Bi2O3. In particular, the sample, filled with 1.5 wt% OMMT, 1.5 wt% Sb2O3, and 27 wt% IFR, passes the UL94 V-0 rating and acquires the highest limiting oxygen index value of 28.5% among the samples. The IFR-OMMT-metal oxide ternary system exerts a better synergistic effect on the generation of crosslinking and aromatic structures that supply the excellent charring effect and barrier effect for the EPs, and the synergistic efficiency of IFR-OMMT-metal oxide ternary system is varied with the types of metal oxides. 相似文献
Candida albicans (CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA− cutaneous lymphocyte antigen (CLA)+/− T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, n = 52), and also healthy individuals (n = 17). A complete proteomic profile was also evaluated in plaque psoriasis patients (cohort 2, n = 114) regarding their anti-CA IgA levels. Increased anti-CA IgA and IgG levels are present in the plasma from plaque but not guttate psoriasis compared to healthy controls. CA cellular response is confined to CLA+ T cells and is primarily Th17. The levels of anti-CA IgA are directly associated with CLA+ Th17 response in plaque psoriasis. Proteomic analysis revealed distinct profiles in psoriasis patients with high anti-CA IgA. C-C motif chemokine ligand 18, chitinase-3-like protein 1 and azurocidin were significantly elevated in the plasma from plaque psoriasis patients with high anti-CA levels and severe disease. Our results indicate a mechanism by which Candida albicans exposure can trigger a clinically relevant IL-17 response in psoriasis. Assessing anti-CA IgA levels may be useful in order to evaluate chronic psoriasis patients. 相似文献