Analysis of solid renal dysplasia by flow cytometry: malignant potential?

The iron-chelating agent desferrioxamine now finds extensive use in the treatment and diagnosis of aluminum-related diseases in renal patients. We review the chemistry and pharmacokinetics of desferrioxamine in chelation therapy for patients on hemodialysis.     

School psychologists and the AIDS epidemic.

Provides an overview of what is known about acquired immune deficiency syndrome (AIDS), AIDS transmissibility, and the modes of transmission. Current and projected incidence rates are reported along with a focus on pediatric AIDS and AIDS in adolescents. The impact of the AIDS epidemic on the nation's school systems and the importance of AIDS education in altering the course of the epidemic are described. The opportunity and responsibility for school psychologists to assume a position of leadership in this crisis and possible psychoeducational interventions and research topics are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

On the wisdom of assertive job-seeking behavior.

Employer ratings of 16 frequently advocated assertive job-seeking behaviors were summarized in terms of whether or not each would enhance or diminish the applicant's chances for being offered employment. These ratings were further subjected to an Applicant Sex?×?Industry Size MANOVA. Data were derived from 272 employers listed as business or industrial organizations in the 1981 College Placement Annual. Some behaviors were clearly adaptive; others appeared to be self-defeating. The applicant's sex proved irrelevant to hiring decisions; however, company size influenced the employment potential of 5 assertive behaviors. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The interaction of strain of Holstein-Friesian cows and pasture-based feed systems on milk yield, body weight, and body condition score

Interactions between genotype and environment are becoming increasingly important as cattle genotypes are being managed in a diverse range of environments worldwide. The objective of this study was to investigate if there is an interaction of strain of Holstein-Friesian cows (HF) by grass-based feed system that affects milk production, body weight, and body condition score. Three strains of HF were compared on 3 pasture-based feed systems over 3 consecutive years. The 3 strains of HF were: high production North American, high durability North American, and New Zealand. The 3 grass-based feeding systems (FS) were: a high grass allowance system (MPFS), a high concentrate system (HCFS), and a high stocking rate system (HSFS). There was a separate farmlet for each FS and a total of 99, 117, and 117 animals were used in yr 1, 2, and 3 respectively, divided equally between strains of HF and FS. The high production cows produced the highest yield of milk, the New Zealand the lowest, and the high durability animals were intermediate. Milk fat and protein content were higher for the New Zealand strain than for the high production and high durability strains. The New Zealand strain had the lowest body weight and the highest condition score, whereas the high durability strain had the highest body weight, and the high production strain had the lowest condition score. There was a strain x FS interaction for yield of milk, fat, and protein. The milk production response to increased concentrate supplementation (MPFS vs. HCFS) was greater with both the high production and high durability strains (1.10 kg of milk/kg of concentrate for high production; 1.00 kg of milk/kg of concentrate for high durability) than the New Zealand strain (0.55 kg of milk/kg of concentrate). The results indicate that the optimum strain of HF will vary with feed system.     

Incremental effects of modeling and performance feedback in teaching decision-making counseling.

In a replicated study involving 54 randomly assigned counselor trainees, 3 cumulative methods of teaching decision-making counseling were compared (a traditional method, a method incorporating a filmed instructional model, and a method featuring several microcounseling components). In both the original study and in the replication the latter method was found to be significantly more effective than either of the former methods in promoting student acquisition of decision-making counseling skills. Incorporation of a filmed instructional model did not significantly improve the traditional method. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Particle size and chemical composition effects on elemental analysis with the nano aerosol mass spectrometer

In the Nano Aerosol Mass Spectrometer (NAMS), particles are irradiated with a high energy laser pulse to produce a plasma that quantitatively disintegrates each particle into positively charged atomic ions. Previous work with this method used electrodynamic focusing and trapping of particles 30 nm dia. and below. In the current work, an aerodynamic focusing inlet was used to study particles between 40 and 150 nm dia. The distribution of atomic ion charge states was found to be particle size dependent, shifting toward lower charges with increasing size. This shift also affected the calibration by which elemental composition was determined from atomic ion signal intensities. Size independent calibration could be achieved by restricting the analysis to particles that gave more than 90% of the total signal intensity as multiply charged ions. This approach worked best for particles smaller than about 100 nm dia. since most spectra met this criterion. For the nanoparticles studied, the elemental mole fractions of Group I and II metals, halogens, and low atomic mass nonmetals could be determined within 10% or less of the expected value when the mole fraction was at the 1% level or greater. Some transition and heavy metals could not be quantified, while others could. Quantification appeared to be dependent on the ability of the element to be vaporized. Elements with high melting and boiling points gave particle mass spectra similar to those obtained by laser desorption ionization—mostly singly charged ions with relative intensities strongly biased toward atoms with low ionization energies.

Copyright © 2017 American Association for Aerosol Research     

Radon in Private Water Supplies: The Unknown Risk

Radon gas, which is the main contributor to human radiation exposure, is easily dissolved in, and dissipated from, water. Problems with radon occur because, in addition to being ingested, it (a) becomes attached to particles which lodge in the lungs and (b) emits alpha radiation. Concentration has been found to increase inversely with the size of a water supply. Although of little problem in mains'water, private water supplies in the UK have been found to contain more than ten times the recommended US levels. Despite this, very little monitoring is carried out for radon in private supplies. Local authorities, situated in areas where the geological conditions are such that high levels of radon would be expected, should carry out a suitable sampling and monitoring programme of their private water supplies.     

A biological and economic comparison of 2 pasture-based production systems on a wetland drumlin soil in the northern region of Ireland

The objective of this study was to compare the biological and economic efficiencies of 2 likely future pasture-based systems of milk production differing in overall stocking rate and concentrate supplementation level on a wetland drumlin soil in the Border Midlands Western region of Ireland. Physical performance data were obtained from a 3-yr systems comparison at Ballyhaise College, Co. Cavan, comparing 2 production systems: a high grass (HG) system (578 kg of concentrate/cow at 2.45 livestock units per hectare) and a high intensity (HI) system (1,365 kg of concentrate/cow at 2.92 livestock units/ha). Animal production data were analyzed using a mixed model, with feed system, year, and parity included as fixed effects in the final model. Feed system had a significant effect on all yield variables with higher yields in the HI system. Production system had no significant influence on reproductive performance. The Moorepark Dairy Systems Model, a stochastic budgetary simulation model, was used to simulate a model farm integrating biological data from each feed system to identify the economic effect of each system at 3 future milk prices of 22, 27, and 33 euro cents per liter (€c/L). Two economic scenarios were investigated within the model: scenario 1 (S1) assumed fixed cow numbers (n=55 cows) and scenario 2 (S2) assumed fixed land area (n=40 ha). At a milk price of 27 or 33 €c/L, profit per cow, per kilogram of milk solids, and per hectare were similar for HG and HI in S1 and higher for HI in S2. At a milk price of 22 €c/L, all systems were unprofitable, with increased losses realized in the HI system (both S1 and S2) compared with the HG system. Pasture-based systems of milk production in the northern region of Ireland are capable of highly efficient and profitable milk production. Moreover, the efficacy of increased supplementation to remove the constraints of pasture seasonality will depend on the cost of supplementation and the price paid for additional milk produced.