Nuclear proteins from liver and kidney bind a 37 bp sequence in the 5' upstream region of the mGAT1 gene

The mouse GABA transporter (mGAT1) gene has been shown to be exclusively expressed in brain by Northern and Western blot analyses. The interactions between the 5' flanking region of the mGAT1 gene and nuclear proteins from different mouse tissues were studied by means of gel-shift assay. Our results show that nuclear protein factors from non-nervous tissues can specifically recognize a 37 bp sequence that is conserved in the 5' flanking region between the human and mouse GAT1 genes. Similar nuclear protein factors were also found to exist in rat, rabbit and pig.     

The small-cell variant of mycosis fungoides. A clinicopathological and quantitative electron microscopic study on 14 patients

Small-cell variants of Sézary syndrome and mycosis fungoides (MF) have been described. However, in these studies the nuclear area of the small-cell variant of MF (SC-MF) as compared to histological classical MF (CL-MF) was not characterized objectively by quantitative electron microscopy. In a 14-year follow-up period, of a total of 76 patch/plaque stage MF patients seen in the Department of Dermatology of the University Hospital Utrecht, 14 (18%) had an infiltrate composed of atypical lymphocytes characterized by a distinctly smaller cell diameter and smaller, hyperchromatic, deeply indented nuclei as compared to the usual cell type of MF. The aim of the investigation was to confirm this observation objectively using quantitative electron microscopy (morphometry) and to define SC-MF as compared to CL-MF. The study was performed on the 14 patients with SC-MF, and 10 patients with clinical and histological CL-MF and 4 patients with chronic eczema. Electron micrographs of sections obtained from each biopsy were analysed by computer to produce the following data: a nuclear contour index (NCI), the mean nuclear area (MNA), the mean nuclear area of the cells above the 75th percentile (P75NA) and the percentage of cells larger than 30 microm2. The values of MNA differed significantly between patients with SC-MF and those with CL-MF (17.6 vs 23.2 microm2; P = 0.02), as did the values of P75NA (20.7 vs 27.9 microm2; P = 0.01). The NCI of the SC-MF and CL-MF patients were similar. These results are consistent with our observations that SC-MF does indeed exist.     

Hierarchical Fuzzy Systems Integrated with Particle Swarm Optimization for Daily Reference Evapotranspiration Prediction: a Novel Approach

Water Resources Management - Reference evapotranspiration (ET0) is a crucial element for deriving irrigation scheduling of major crops. Thus, precise projection of ET0 is essential for better...     

RFID-based interactive multimedia system for the children

In this paper, we present an interactive edutainment system for the children that leverages multimedia and RFID technologies in a seamless manner. The proposed system allows children to learn about new objects/entities by tapping on physical objects through a specially designed RFID-Bluetooth based Tangible User Interface (TUI) tool. The output of the system is delivered as a set of appropriate multimedia representations related to the objects being tapped. The TUI uses RFID technology for object identification and Bluetooth communication to transmit data to the computer where the system??s software is running. We incorporated our system in three games that allow children of different ages to benefit from the system??s functionalities and encourage them to interact with it.     

Determining trust in media-rich websites using semantic similarity

Significant growth of multimedia content on the World Wide Web (or simply ??Web??) has made it an essential part of peoples lives. The web provides enormous amount of information, however, it is very important for the users to be able to gauge the trustworthiness of web information. Users normally access content from the first few links provided to them by search engines such as Google or Yahoo!. This is assuming that these search engines provide factual information, which may be popular due to criteria such as page rank but may not always be trustworthy from the factual aspects. This paper presents a mechanism to determine trust of websites based on the semantic similarity of their multimedia content with already established and trusted websites. The proposed method allows for dynamic computation of the trust level of websites of different domains and hence overcomes the dependency on traditional user feedback methods for determining trust. In fact, our method attempts to emulate the evolving process of trust that takes place in a user??s mind. The experimental results have been provided to demonstrate the utility and practicality of the proposed method.     

A replacement of traditional insulation refractory brick by a waste-derived lightweight refractory castable

Lightweight insulation refractories are essential for high-temperature performance to reduce energy consumption. This study investigates a new insulation material, that is, solid waste rice husk ash (RHA) derived lightweight refractory castable, replacing traditional insulation refractory brick. The RHA is generated after the burning of rice husk as biomass fuel. The RHA is used as an aggregate and alkali-extracted silica sol from RHA as a binder to fabricate the insulation castable. The nanosilica containing (~30 wt%) sol is employed to synthesize the refractory castable by varying the sol amount (2.5-12.5 wt% silica from sol). The castable specimens are cast by a vibro-caster and fired at 900-1200°C in a muffle furnace. The physic-mechanical and thermal conductivity (κ) of the castable is investigated. At 1100°C with 10 wt% dry sol retaining sample shows an excellent apparent porosity (~65%), low bulk density (~ 0.8 g/cm³), and κ (0.136 W/m k) with sustainable compressive strength (6 MPa). The acquired results are a good match with the literature (other wastes-derived insulation materials) and industrial (silica insulation brick) obtained data. These promising outcomes may inspire the refractory industries for using RHA as an aggregate and RHA extracted sol as a binder for making insulation castable.     

QoS-aware service composition for distributed video surveillance

Quality of Service (QoS) is essential for the ubiquitous access of media services in real-time distributed video surveillance applications. To have ubiquitous access of desired media with emergency officials’ handheld devices, appropriate media transcoding services are required. Currently, it is challenging to select and compose these services for each of the devices to satisfy the desired QoS demand. To compose these media services so that video stream is available for target pervasive and smart devices, a composition algorithm is required. Thus, this paper presents a QoS-aware service composition algorithm to select the best composition for the target ubiquitous client so that it can optimally provide QoS to heterogeneous users. We have implemented a video surveillance prototype to demonstrate the performance of the proposed QoS-aware composition algorithm. Results from this prototype reveal that the approach is suitable for real-time video surveillance.     

A personal meeting scheduling agent

When setting up a meeting, meeting participants need to reach a mutual agreement to hold the meeting subject to their personal constraints and preferences. It is a time-consuming process, and a variety of calendaring applications are in use assisting users to schedule meetings. Software applications failed to overcome the constraints of the traditional-scheduling process and works as a supporting tool for managing meeting information. One of the main constraints in automated scheduling is the unavailability of a standard structured communication protocol. In addition, automated scheduling requires other issues to be considered such as automated decision-making paradigm, negotiation strategy selection mechanism, etc. This paper proposes a personal meeting scheduling agent (PMSA) and a personal meeting scheduling protocol (PMSP). PMSP is embedded in the PMSA for handling bilateral and multilateral negotiations. PMSA is designed using model-based, goal-based methodology. Additionally, PMSP is designed following a structured negotiation protocol influenced by simultaneous response protocol. To evaluate all meeting invitations and to make decisions subject to users’ preferences, participants’ profiles, and the schedule availability, this paper utilizes the naïve Bayes model of maximum likelihood Estimation. The PMSP goal is to automatically make decisions and select the appropriate negotiation strategies to avoid or resolve possible meeting conflicts. To demonstrate the feasibility of the proposed PMSP, a simulation environment with experimental results is presented.