TRIP带钢轧后冷却过程温度场的有限元模拟

应用有限元模拟仿真计算，对相变诱发塑性(TRIP)带钢在连轧机精轧后由850～890℃快冷至700℃，经几秒钟短暂空冷再第2次快速水冷至卷取温度400℃的冷却过程的温度进行了分析计算。分析结果得出，3mmTRIP带钢厚度方向的温差较小，而8mmTRIP带钢厚度方向温差明显增大。因此TRIP带钢在2次快速冷却后和卷取前应有适当的空冷时间以降低TRIP带钢卷取时表面和厚度方向中心处的温度差。     

稳定化处理工艺参数对预应力钢绞线性能的影响

通过对预应力（ＰＣ）钢绞线稳定化处理及随后的破断、应力松驰试验，分析了处理前后强度、塑性、松驰率指标的变化趋势，得出了工艺温度、张应力对性能指标的影响规律，进而提出稳定化处理的最佳工艺参数。     

Procedural Synthesis using Vortex Particle Method for Fluid Simulation

We propose a fast and effective technique to improve sub‐grid visual details of the grid based fluid simulation. Our method procedurally synthesizes the flow fields coming from the incompressible Navier‐Stokes solver and the vorticity fields generated by vortex particle method for sub‐grid turbulence. We are able to efficiently animate smoke which is highly turbulent and swirling with small scale details. Since this technique does not solve the linear system in high‐resolution grids, it can perform fluid simulation more rapidly. We can easily estimate the influence of turbulent and swirling effect to the fluid flow.     

Comments on “Wirtinger-based integral inequality: Application to time-delay systems [Automatica 49 (2013) 2860–2866]”

In a recent paper (Automatica 49 (2013) 2860–2866), the Wirtinger-based inequality has been introduced to derive tractable stability conditions for time-delay or sampled-data systems. We point out that there exist two errors in Theorem 8 for the stability analysis of sampled-data systems, and the correct theorem is presented.     

地埋管地源热泵水系统的若干问题研究

结合调研测试的实际工程,根据实际工程中地埋管地源热泵系统中水系统的形式及特点,归纳了设计、运行管理、设备故障等几个方面的水系统常见的问题。探讨了地埋管地源热泵水系统的设计问题,指出某些工程水系统存在的问题及解决思路;分析水系统故障的原因及表现,通过对水系统运行状态的观察与测试,从机组COP及系统能效比的角度分析水系统故障的影响：对于运行管理方面,提出相应的水系统形式的运行建议,为优化地埋管地源热泵的设计及运行管理提供了相应参考。     

Creation of Nonspherical Microparticles through Osmosis‐Driven Arrested Coalescence of Microfluidic Emulsions

Droplet‐based microfluidics enable the production of emulsions and microparticles with spherical shapes, but the high‐throughput fabrication of nonspherical emulsions and microparticles still remains challenging because interfacial tension plays a dominant role during preparation. Herein, ionic liquids (ILs) containing salts, which possess sufficient osmotic pressure to realize water transport and phase separation, are introduced as inner cores of oil‐in‐oil‐in‐water double emulsions and it is shown that nonspherical emulsions can be constructed by osmosis‐driven arrested coalescence of inner cores. Subsequently, ultraviolet polymerization of the nonspherical emulsions leads to nonspherical microparticles. By tailoring the number, composition, and size of inner cores as well as coalescence time, a variety of nonspherical shapes such as dumbbell, rod, spindle, snowman, tumbler, three‐pointed star, triangle, and scalene triangle are created. Importantly, benefitting from excellent solvency of ILs, this system can serve as a general platform to produce nonspherical microparticles made from different materials. Moreover, by controlling the osmotic pressure, programmed coalescence of inner cores in double emulsions is realizable, which indicates the potential to build microreactors. Thus, a simple and high‐throughput strategy to create nonspherical microparticles with arrested coalescence shapes is developed for the first time and can be further used to construct novel materials and microreactors.     

Studied on a novel human keratinocyte membrane delivery system in vitro

The culture of keratinocytes on flexible membranes has been proposed as a means to simplify, accelerate and improve the efficiency with which proliferating cells are delivered to full thickness or non-healing skin defects. The purpose of this article was to study the ability of chitosan-gelatin manbranes to facilitate the growth of human keratinocytes. The membranes with different chitosan contents were studied. The surface properties of chitosan-gelatin membranes were investigate by SEM, and water contact angle test. The mechanical property of the membranes was tested. Data implied that gelatin could make the membranes more flexible and hydrophilic than chitosan membranes, which may regulate the seeded cells behavior. Loading human keratinocytes on chitosan-gelatin membranes, cells attachment, spread, and growth were investigated by light microscopy, SEM, and MTT test. The results suggested that the adhesion and proliferation of keratinocytes seeded on chitosan-gelatin membranes were same as on tissue culture plate, in which gelatin could modify the interaction between keratinocytes and chitosan membranes. Therefore, chitosan-gelatin membrane is a good candidate for keratinocytes delivery system.     

Coating of TiO2 nanoparticles with PbS thin films and preparation of PbS nanoparticles using a one-pot sonochemical reaction under the multibubble sonoluminescence conditions

Preparations of PbS-coated titanium dioxide (TiO₂) and lead sulfide (PbS) nanoparticles under ultrasonic field at the multibubble sonoluminescence (MBSL) conditions were tested in water solutions. Under the optimal MBSL conditions (20 kHz and 220 W power input), PbS nanoparticles (diameter = 40-50 nm) were prepared by treating lead nitrate and thioacetamide for 20 min in water solutions. The size of PbS nanoparticles was found to be easily increased to about 90 nm in diameter by increasing the reactant concentration twice. A similar sonochemical reaction with TiO₂ nanoparticles (about 20-30 nm in diameter) gave rise to PbS-coated TiO₂ nanoparticles with a core/shell structure. The PbS thin film coating was quite uniform and the average coating depth of PbS on the TiO₂ nanoparticles was about 2-3 nm under the described conditions. It is interesting to note that the coating depth was found to be controlled to 2-10 nm range by increasing the amounts of reactants for Pb and S twice with a sonication time of 30 min.     

Neuronal ApoE Regulates the Cell-to-Cell Transmission of α-Synuclein

The presence of protein inclusions, called Lewy bodies (LBs) and Lewy neurites (LNs), in the brain is the main feature of Parkinson’s disease (PD). Recent evidence that the prion-like propagation of α-synuclein (α-syn), as a major component of LBs and LNs, plays an important role in the progression of PD has gained much attention, although the molecular mechanism remains unclear. In this study, we evaluated whether neuronal ApoE regulates the cell-to-cell transmission of α-syn and explored its molecular mechanism using in vitro and in vivo model systems. We demonstrate that neuronal ApoE deficiency attenuates both α-syn uptake and release by downregulating LRP-1 and LDLR expression and enhancing chaperone-mediated autophagy activity, respectively, thereby contributing to α-syn propagation. In addition, we observed that α-syn propagation was attenuated in ApoE knockout mice injected with pre-formed mouse α-syn fibrils. This study will help our understanding of the molecular mechanisms underlying α-syn propagation.     

氢氧发动机多余物防控设计

由于多余物的危害及航天产品高精尖的发展需要,多余物防控设计已成为产品设计不可或缺的设计准则.通过对氢氧发动机多余物的特点进行分析,发动机明确了介质精度控制要求并进行了过滤器的设计,可有效对多余物进行防控.针对氢氧发动机的低温特点,还进行了发动机"潮气及未置换干净的空气"的防控设计以防"冰堵".