A statistical analysis of the received signal from blood duringlaminar flow

In order to determine the limiting velocity resolution that can be achieved using ultrasound, and to provide a model which can be generalized for the analysis of disturbed flow, a theoretical and experimental evaluation of the statistics of the received signal from laminar flow following the transmission of a train of short pulses is presented. The authors derive the autocorrelation function and determine the length of the correlated signal for various flow rates, comparing experimental measurements to theoretical predictions. High resolution experimental RF M-mode images are used to verify the theoretical model. Using a fluid with a density, viscosity, volume concentration, particle size, and speed of sound which is similar to that of blood, the authors show that the signal remains correlated for a long interval under many conditions of clinical interest. Including a comparison with experimental data, the effect of the lateral transit time through the sample volume and the axial velocity spread within the sample volume on the correlation of the received signal is evaluated. When a significant range of velocity components is present within the sample volume, this range is the limiting factor in the length of the correlated signal interval. Therefore, the use of a wideband signal, which reduces the sample volume size, produces a returned signal that may be correlated for a larger number of pulses, or for a longer time     

Enhancement Effects in the Percutaneous Absorption of Alprazolam Through Human Skin in vitro

The enhancement effects of some chemicals on the percutaneous absorption of alprazolam through human skin was investigated in vitro. Linoleic acid, oleic acid, Comperlan F® (linoleic acid diethanolamide), Comperlan KD® (coconut fatty acid diethanolamide) and Ethomeen C12® (bis-(2-hydroxyethyl)cocamine) were evaluated for their enhancing effect either as neat solvents or combined with propylene glycol. The effects of skin pretreatment with the enhancers on the percutaneous absorption of alprazolam from a drug suspension in an aqueous gel were also investigated: skin pretreatment with some enhancers has shown potentially interesting aspects. The determination of alprazolam partitioning into untreated and pretreated horny layer supported the idea that, with oleic and linoleic acid, a contribution to the modification of the diffusional resistance of the skin was given by an increase of the drug solubility in the stratum coraeum.     

Mechanisms of deformation and fracture of multilayer coatings during thermal cycling

Damage to multilayer coatings under thermal cyclic loading is investigated. The mechanisms of crack formation are established and studied as a function of the composition of the coatings, the base metal, and the form of cycle. On the basis of these results, we suggest a composition of multilayer coating with high heat resistance.Science and Production Department, Polzunov Central Design and Technological Institute, St. Petersburg. Translated from Fiziko-Khimicheskaya Mekhanika Materialov, Vol. 29, No. 6, pp. 48–55, November–December, 1993.     

A process algebraic approach to the specification and analysis ofresource-bound real-time systems

Recently, significant progress has been made in the development of timed process algebras for the specification and analysis of real-time systems. This paper describes a timed process algebra called ACSR, which supports synchronous timed actions and asynchronous instantaneous events. Timed actions are used to represent the usage of resources and to model the passage of time. Events are used to capture synchronization between processes. To be able to specify real systems accurately, ACSR supports a notion of priority that can be used to arbitrate among timed actions competing for the use of resources and among events that are ready for synchronization. The paper also includes a brief overview of other timed process algebras and discusses similarities and differences between them and ACSR     

A partitioning technique for the finite element solution ofelectromagnetic scattering from electrically large dielectric cylinders

A finite element partitioning scheme has been developed to reduce the computational costs of modeling electrically large geometries. In the partitioning scheme, the cylinder is divided into many sections. The finite element method is applied to each section independent of the other sections, and then the solutions in each section are coupled through the use of the tangential field continuity conditions between adjacent sections. Since the coupling matrix is significantly smaller than the original finite element matrix, it is expected that both the CPU time and memory costs can be significantly reduced. The partitioning scheme is coupled to the bymoment method to account for the boundary truncation. Numerical results are presented to demonstrate the efficiency and accuracy of the method     

Experiments on hot electron noise in semiconductor materials forhigh-speed devices

Experimental results on noise temperature and spectral density of current fluctuations (electron diffusion) at high electric fields in silicon, gallium arsenide, and indium phosphide are presented. The dominant noise sources are discussed in their relation to electron scattering mechanisms. Physical backgrounds of high speed-low noise performance (noise-speed tradeoff) are considered. Suppression in short samples of the fluctuations having long correlation time constant and (or) high threshold energy is discussed     

Call control and traffic transport for connection-oriented highspeed wireless personal communications over metropolitan area networks

A distributed circuit-switched approach for supporting the deployment of high speed wireless personal communication services in urban areas through the interconnection of base stations via metropolitan area networks (MANs) is proposed. Broadband MANs minimize traffic congestion by dynamic sharing of link capacity and by serving as distributed switches for partitioning call control functions. While the DQDB protocol readily supports distributed packet-switching over the IEEE 802.6 MAN, isochronous traffic such as voice and video is best supported by circuit-switched connections. The authors present an enhanced bi-state pre-arbitrated (PA) transport mechanism, and associated call control and handoff management techniques, which enable distributed circuit-switching over the MAN. These capabilities are not currently addressed in the 802.6 standards. The bi-state PA transport mechanism facilitates statistical multiplexing of variable rate isochronous traffic sources. The network capacity is constrained by the call setup delay performance, and is analyzed by simulations. Alternative signaling architectures, involving different placements of call control network elements, are evaluated. The effects of erasure nodes, and close bus versus open bus architectures, are considered. The overlap inter-MAN call setup procedure is proposed to reduce delays. Different call handoff procedures are formulated according to the type of handoff and the resulting change in call connectivity. Most handoffs are intra-MAN, requiring simple procedures with short delays