Status of iodine deficiency in selected blocks of Kangra District, Himachal Pradesh

Using polymerase chain reaction single strand conformational polymorphism (PCR-SSCP) and EB staining technique, paraffin-embeded sections of 20 hydatidiform mole and 4 choriocarcinoma were detected in the exons 5 and 8 of p53 gene. The results showed that mutations of p53 gene were 0/9 in the normal chorionic villi, 6/20 (30%) in hydatidiform mole and 3/4 in choriocarcinoma. This study suggests that mutations of p53 gene may be an important event in human gestational trophoblastic neoplastigenesis and its progression.     

Activation of platelets exposed to shear stress in the presence of smoke extracts of low-nicotine and zero-nicotine cigarettes: the protective effect of nicotine.

Mainstream and sidestream smoke extracts of both high-tar and low-tar cigarettes have been shown to increase platelet activation directly and to sensitize them to further activation by exposure to mechanical stimuli such as shear stress. However, nicotine has an inhibitory effect on platelet activation, opposite to that of whole cigarette smoke extracts. To distinguish between the nicotine-dependent and non-nicotine-dependent effects of smoke, platelets were exposed to mainstream and sidestream smoke extracts of low-nicotine and zero-nicotine cigarettes in vitro under flow conditions comparable with the normal circulation, and their activation state was measured using a modified prothrombinase-based assay. Both low-nicotine and zero-nicotine extracts caused increased platelet activation upon exposure to shear stress, and they caused significantly greater activation than extracts from ordinary high-tar, high-nicotine cigarettes. That nicotine was crucial was confirmed by adding 50 nM nicotine (comparable with the nicotine level in smokers' plasma) to zero-nicotine smoke extracts and demonstrating a reduction in the shear-dependent rate of platelet activation of more than 75%.     

Dispersion-tailored few-mode fibers: a versatile platform for in-fiber photonic devices

In-fiber devices enable a vast array of critical photonic functions ranging from signal conditioning (amplification, dispersion control) to network management (add/drop multiplexers, optical monitoring). These devices have become mainstays of fiber-optic communication systems because they provide the advantages of low loss, polarization insensitivity, high reliability, and compatibility with the transmission line. The majority of fiber devices reported to date are obtained by doping, designing, or writing gratings in the core of a single-mode fiber (SMF). Thus, these devices use the fiber only as a platform for propagating light-the device effect itself is due to some extraneously introduced material or structure (dopants for amplification, gratings for phase matching, etc.) There exists another, relatively less explored degree of freedom afforded by fibers-the ability to copropagate more than one mode. Each mode may have a uniquely defined modal dispersion and propagation characteristic. In this paper, we will describe the variety of fiber devices enabled by few-mode fibers-fibers that typically support two to four modes with suitably tailored dispersive properties. We will show that the unique dispersive properties of various modes, in conjunction with the ability to couple between them with gratings, leads to devices that offer novel solutions for dispersion compensation, spectral shaping, and polarization control, to name a few.     

An implementation of distributed shared memory

Shared memory is a simple yet powerful paradigm for structuring systems. Recently, there has been an interest in extending this paradigm to non-shared memory architectures as well. For example, the virtual address spaces for all objects in a distributed object-based system could be viewed as constituting a global distributed shared memory. We propose a set of primitives for managing distributed shared memory. We present an implementation of these primitives in the context of an object-based operating system as well as on top of Unix.     

An Efficient Parallel Algorithm for the Layered Planar Monotone Circuit Value Problem

A planar monotone circuit (PMC) is a Boolean circuit that can be embedded in the plane and that contains only AND and OR gates. A layered PMC is a PMC in which all input nodes are in the external face, and the gates can be assigned to layers in such a way that every wire goes between gates in successive layers. Goldschlager, Cook and Dymond, and others have developed NC ² algorithms to evaluate a layered PMC when the output node is in the same face as the input nodes. These algorithms require a large number of processors (Ω(n ⁶ ), where n is the size of the input circuit). In this paper we give an efficient parallel algorithm that evaluates a layered PMC of size n in time using only a linear number of processors on an EREW PRAM. Our parallel algorithm is the best possible to within a polylog factor, and is a substantial improvement over the earlier algorithms for the problem. Received April 18, 1994; revised April 7, 1995.     

Electrolytic recovery of zinc from zinc ash using a catalytic anode

The process of galvanisation of steel generates zinc ash as the waste product, thus creating pollution problems. The recovery of zinc metal from zinc ash, with a zinc content of about 76% by leaching and electrowinning has been studied. The presence of chloride has been identified as the major problem area. A catalytic anode based on iridium dioxide (IrO₂) was used as the anode material to overcome this problem. Catalyst loading was kept at an economically acceptable level. The catalyst's stability, energy consumption and efficiency of zinc recovery are discussed. The service life of the IrO₂ active coating has been established by an accelerated polarisation test. The zinc deposit recovered from the zinc ash has been examined by X‐ray diffraction (XRD) and scanning electron microscopy (SEM). Copyright © 2004 Society of Chemical Industry     

A 3.3-V CMOS adaptive analog video line driver with low distortion performance

An analog line driver for video applications is presented. Utilizing a class-AB error amplifier structure, the design achieved 1.2-V peak-to-peak output swing with better than 42-dB linearity for frequencies up to 5 MHz. An adaptive tuning scheme for output impedance matching using peak detection is used to provide uniform performance across line impedance variations. The circuit is designed in AMI 0.5-/spl mu/m CMOS technology and has a tuning range of 70-180 /spl Omega/ with a power consumption of about 26.4 mW at 75-/spl Omega/ load.     

Development of indigenous technology for production of titanium sponge by the Kroll process

Titanium has emerged as a major structural metal for a wide range of industrial applications due to its attractive engineering properties. India has a large and rich reserve base for this metal in the beach sands of the eastern and southern regions with well established production facilities for their separation into individual minerals. Research and Development activities for establishing the metal production technology have been underway in the country for over two decades. The Defence Metallurgical Research Laboratory, Hyderabad, has already demonstrated the metal production technology by the conventional Kroll process on 2000 kg/batch scale and is now all set for demonstrating the same by the more advanced, energy efficient combined process route on 4000 kg/batch scale. The paper reviews the R & D efforts undertaken so far in the field of metal extraction with emphasis on the current status of this developmental activity at DMRL.     

Hydration and strength characteristics of synthetic Al-, Mg- and Fe alites

Alites containing different amounts of Al, Mg or Fe were hydrated up to 30 days and their kinetics of hydration and compressive strengths were determined. At the same degree of hydration Fe-alites showed greatest strength. There was evidence that the nature of C?S?H formed in different alites is not the same.