Model of Environmental Membrane Field for Transmembrane Proteins

The water environment determines the activity of biological processes. The role of such an environment interpreted in the form of an external field expressed by the 3D Gaussian distribution in the fuzzy oil drop model directs the folding process towards the generation of a centrally located hydrophobic core with the simultaneous exposure of polar residues on the surface. In addition to proteins soluble in the water environment, there is a significant group of membrane proteins that act as receptors or channels, including ion channels in particular. The change of the polar (water) environment into a highly hydrophobic (membrane) environment is quite radical, resulting in a different hydrophobicity distribution within the membrane protein. Modification of the notation of the force field expressing the presence of the hydrophobic environment has been proposed in this work. A modified fuzzy oil drop model with its adaptation to membrane proteins was used to interpret the structure of membrane proteins–mechanosensitive channel. The modified model was also used to describe the so-called negative cases—i.e., for water-soluble proteins with a clear distribution consistent with the fuzzy oil drop model.     

Rubber substrates and their influence on isomerization of conjugated dienes in pheromone dispensers

Release rate and degree of isomerization of pheromones with conjugated double bonds were studied in dispensers prepared from several rubber substrates. The substrates compared were made of rubber, cured with elemental sulfur or accelerators based on organic sulfur compounds or organic peroxides. Isomerization of the double bonds occurs immediately after impregnation of the substrate, and the degree of isomerization increases during field use and/or storage. The propensity of the isomers to isomerize corresponds to their proportion in the equilibrium mixture. AnE,Z isomer is isomerized faster than theE,E isomer, and finally a near-equilibrium mixture of the four isomers is present. Minimal isomerization was found in non-sulfur-cured substrates which are the material of choice.     

Food-motivated behavior in rats with cortico-basomedial amygdala damage.

In 6 experiments, 12 male Wistar rats with cortico-basomedial amygdala damage (CBM) and 20 sham-operated controls were tested in several food-related situations. The CBM Ss showed a longer latency to eat than controls in a novel environment due to more pronounced exploration. In the competition for food, CBM Ss lost 85% of encounters with controls. Immediately after the contest, when allowed to eat singly, CBM Ss displayed a higher persistence of alimentary responses to an emptied cup than did controls, presumably because they experienced more losses in the food competition. Both groups were equally able to overcome obstacles on the way to food, which suggested similar alimentary motivation. The only direct indication of a lowered responsiveness to hunger in CBM Ss was 24-hr fasting-induced hypophagia. Results indicate the involvement of the cortico-basomedial amygdaloid region in the control of relations between alimentary and other motivations. The contribution of eventual changes of food motivation in the postoperative alteration of this balance is discussed. (30 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

What can a country with small nuclear program learn from other European countries?

In this paper the present status of the nuclear programme and radioactive waste management in Slovenia is briefly presented. The quantities of accumulated radioactive wastes are given and the storage capacities and plans and problems concerning the final disposal are described. Because of small nuclear programme and limited resources Slovenia cannot afford expensive research and development projects; therefore, in selecting the optimal long-term solution for its radioactive waste foreign experience and approaches are very important. Intercomparison of solutions in different areas of radioactive waste management in more developed countries can be of great help to such countries when the disposal programme is prepared, as is indicated in this paper.     

Lipidomic Analysis: From Archaea to Mammals

Lipids are among the most important organic compounds found in all living cells, from primitive archaebacteria to flowering plants or mammalian cells. They form part of cell walls and constitute cell storage material. Their biosynthesis and metabolism play key roles in faraway topics such as biofuel production (third‐generation biofuels produced by microorganisms, e.g. algae) and human diseases such as adrenoleukodystrophy, Zellweger syndrome, or Refsum disease. Current lipidomic analysis requires fast and accurate processing of samples and especially their characterization. Because the number of possible lipids and, more specifically, molecular species of lipids is of the order of hundreds to thousands, it is necessary to process huge amounts of data in a short time. There are two basic approaches to lipidomic analysis: shotgun and liquid chromatography–mass spectometry. Both methods have their pros and cons. This review deals with lipidomics not according to the type of ionization or the lipid classes analyzed but according to the types of samples (organisms) under study. Thus, it is divided into lipidomic analysis of archaebacteria, bacteria, yeast, fungi, algae, plants, and animals.     

Influence of the structure of polymer fiber composites on the analysis of the zeta potential

This article addresses the questions about the influence of surface area, roughness, and sample mounting on the zeta potential analysis. A series of knitted yarns and fabrics of cotton and modacryl and their blends represent a real‐life model system to study these effects. The combination of the natural cotton and the man‐made modacryl makes possible to study the effect of the different origin for surface and interfacial charge and the surface area‐weighted contributions to the average zeta potential of a chemically heterogeneous composite material. In our study, two measuring cells of the SurPASS electrokinetic analyzer were used, namely the Cylindrical Cell and the Adjustable Gap Cell. Comparison of the results obtained in two different measuring cells was related to the measured material. We used the Cylindrical Cell for both the zeta potential analysis of yarn and knitted fabrics and compared these results with data obtained for knitted fabrics using the Adjustable Gap Cell. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 46227.     

An algorithm for robust image watermarking based on the DCT and Zernike moments

An image watermarking scheme in the 2D DCT domain is proposed by exploring the advantages of using Zernike moments. Zernike transform has been used in image processing applications such as image recognition, authentication, protection, etc. Here, we propose to use the Zernike moments of the DCT transform to provide an efficient watermarking method. Particularly, the novelty of the proposed approach relies on the method for selection of features that will enable both preserving the image quality and robustness to attacks. Also, a criterion for selection of image blocks suitable for watermarking is given. It is based on the ? ₁-norm of Zernike moments. The efficiency of the proposed watermarking algorithm is proved on several examples considering different types of attacks (compression, noise, filtering, geometrical attacks).     

Biocompatible surface modification of poly(ethylene terephthalate) focused on pathogenic bacteria: Promising prospects in biomedical applications

Poly(ethylene terephthalate)—PET, is one of the most common polyesters, widely used in biomedical applications ranging from catheters to stents, vascular grafts, heart valves, sutures, and scaffolds. PET surface modification is necessary to impart desired properties for biomedical applications, making the polymer biocompatible, noncytotoxic and antibacterial that can preferably resist biofilm formation caused by pathogenic bacteria. A novel approach to anticorrosive wet chemical surface modification of PET by insertion of alkyl and hydroxyl groups was achieved by using Grignard reagents and confirmed by several different characterization methods including Fourier transform infrared spectroscopy (FTIR), water contact angle (WCA) measurement, free surface energy (FSE) measurement, scanning electron microscopy (SEM), and atomic force microscopy (AFM). High antibacterial efficiency against four different types of biofilm active, pathogenic bacterial strains namely: Staphylococcus aureus, Escherichia coli, methicillin‐resistant S. aureus (MRSA), and Pseudomonas aeruginosa was established on the modified PET surface. Biocompatibility higher than 84% of the modified samples has been proved. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134, 44990.