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11.
J. L. Bocos E. Novillo M. M. Petite A. Iza-Mendia I. Gutierrez 《Metallurgical and Materials Transactions A》2003,34(3):827-839
The present work concentrates on the application of orientation imaging microscopy (OIM) based on the electron backscattered
diffraction (EBSD) technique to the investigation of the microstructural evolution of an extra-low carbon (ELC) steel and
a Ti-Nb-bearing interstitial-free (IF) steel, during continuous annealing. Aspects like the nucleation, the evolution of the
recrystallized volume fraction and grain size of grains with different orientations, the interface area limiting recrystallized
{111} regions, and the apparent growth rates have been considered. Different criteria have been applied in order to identify
crystallites produced during annealing. During the first stages of annealing, a network of grain boundaries with misorientations
higher than 10 deg is produced, mainly inside the deformed γ-fiber grains. The crystallites formed within this network, free from cells or subgrains at their interiors, can be considered
as potential nuclei. However, among all, only some of them become effective due to an important selection. The {111} recrystallized
grains have a significant size and number advantage as compared with other texture components, and a hard impingement between
clusters of {111} grains is produced during grain growth. The effect of grain growth behind the recrystallization front seems
to be negligible as compared with the grain coarsening produced by the migration of this front, driven by the cold-work stored
energy. 相似文献
12.
We study the behavior of disk assemblies with a variable disorder distribution. The packing is first consolidated and then continuously tilted very slowly. The amount of displaced disks for each tilted angle is recorded. Large displacements of the disks can occur due to some local or global mechanical instabilities. The definition of neighboring disks is based on radical (extension of Voronoï) tessellation rules to decompose, in a unique and perfectly defined manner, the two-dimensional space for polydisperse disks. In this way, by comparing the characteristics of stability for one disk to the neighboring ones for local ordered cluster, we can predict the global amount of displaced disks. Some tilting cycles have been performed to check the correlation between the instability of the packing structure (collective displacements) with micro and macro order parameters. 相似文献
13.
Participating media with an inhomogeneous index of refraction make light follow curved paths. Simulating this in a global
illumination environment has usually been neglected due to the complexity of the calculations involved, sacrificing accurate
physical simulations for efficient visual results.
This paper aims to simulate non-linear media in a more reasonable time than previous works without losing physical correctness.
Accuracy is achieved by solving the Eikonal equation of geometrical optics, which describes the path followed by a light beam
that traverses a non-linear medium. This equation is used in the context of a photon mapping extension. 相似文献
14.
F.J. Rodriguez L.A. García de la Rosa A. Alatorre J. Ibaez L. Godinez S. Gutierrez P. Herrasti 《Progress in Organic Coatings》2007,60(4):297-302
This paper reports the capacity of polypyrrole to reduce toxic hexavalent chromium (Cr(VI)). The influence of using different electrolytes during the polymer's synthesis has been studied. To improve the reduction of Cr(VI), the parameters considered were the polypyrrole morphology and the amount of conducting polymer. Polypyrrole obtained by cyclic voltammetry at a low sweep rate using KBr as supporting electrolyte showed better performance for Cr(VI) reduction compared to coatings obtained by constant potential or cyclic voltammetry at high sweep rates. 相似文献
15.
SF Brenière W Morochi MF Bosseno J Ordo?ez T Gutierrez F Vargas N Yaksic F Noireau 《Canadian Metallurgical Quarterly》1998,71(3):269-283
Triatoma sordida is the second species of Triatominae considered of epidemiological significance in Bolivia. Associated with Triatoma infestans in various regions, it is as yet the only triatomine species established in human dwellings in localities of Velasco province, Department of Santa Cruz. This domestication is considered as primary. Flagellate parasites were detected in 16.2% of domiciliary T. sordida and the kDNA-PCR confirmed the presence of Trypanosoma cruzi. Frequencies of T. cruzi clonets 20 and 39, common clonets in Bolivian domestic cycle (T. infestans), were established by their direct detection in feces using PCR and hybridization. These clonets present low frequencies in T. sordida and synanthropic mammals. Forty-six stocks were isolated and analysed by multilocus enzyme electrophoresis (MLEE). The MLEE showed a higher clonal diversity than in T. infestans domestic cycle and the genotypes were clustered in the two principal lineages of T. cruzi. Within each lineage, a broad variability was observed. Mixture of genotypes was mostly observed in mammals. The large diversity of T. cruzi in this cycle should be related to its sylvatic origin. Moreover, the current limited sample of stocks suggests a lineage association with specific hosts. 相似文献
16.
The influence of several sinter-HIP variables on the densification behaviour of silicon nitride-based ceramics has been investigated. The processing conditions were studied for Si3N4 powder mixtures containing controlled amounts of Y2O3+Al2O3 or Y2O3+MgO. The specimens were subjected to sinter-HIP cycles under argon or nitrogen atmospheres at various temperatures and pressures. The final density of the powder compacts exhibited a strong dependence not only on the applied pressure, the composition and the processing temperature, but also on the pressurization rate and the initial pressurization time. The microstructural changes induced by the application of high pressure were followed by transmission electron microscopy. On examination by TEM, large concentrations of dislocations, generated inside some-Si3N4 grains, were observed. Characterization of these dislocations showed thatb=0001 is their most frequently found Burgers vector. Also, two relaxation mechanisms, tending to release the stored energy of deformation in the-Si3N4 grains, namely grain penetration (a form of strain-induced boundary migration) and grain fragmentation (the formation of subgrains due to rearrangement of dislocations into low energy configurations), have been identified. The intergranular phases formed were characterized by energy dispersive X-ray spectroscopic analysis, X-ray diffraction and electron diffraction. The influence of different sinter-HIP cycles on the transformation of silicon nitride without additives was also investigated by X-ray diffractometry. 相似文献
17.
Julia Peas-Martínez María N. Barrachina Ernesto Jos Cuenca-Zamora Gins Luengo-Gil Susana Beln Bravo Eva Caparrs-Prez Raúl Teruel-Montoya Jos Eliseo-Blanco Vicente Vicente ngel García Irene Martínez-Martínez Francisca Ferrer-Marín 《International journal of molecular sciences》2021,22(4)
Exosomes are extracellular vesicles that contain nucleic acids, lipids and metabolites, and play a critical role in health and disease as mediators of intercellular communication. The majority of extracellular vesicles in the blood are platelet-derived. Compared to adults, neonatal platelets are hyporeactive and show impaired granule release, associated with defects in Soluble N-ethylmaleimide-sensitive fusion Attachment protein REceptor (SNARE) proteins. Since these proteins participate in biogenesis of exosomes, we investigated the potential differences between newborn and adult plasma-derived exosomes. Plasma-derived exosomes were isolated by ultracentrifugation of umbilical cord blood from full-term neonates or peripheral blood from adults. Exosome characterization included size determination by transmission electron microscopy and quantitative proteomic analysis. Plasma-derived exosomes from neonates were significantly smaller and contained 65% less protein than those from adults. Remarkably, 131 proteins were found to be differentially expressed, 83 overexpressed and 48 underexpressed in neonatal (vs. adult) exosomes. Whereas the upregulated proteins in plasma exosomes from neonates are associated with platelet activation, coagulation and granule secretion, most of the underexpressed proteins are immunoglobulins. This is the first study showing that exosome size and content change with age. Our findings may contribute to elucidating the potential “developmental hemostatic mismatch risk” associated with transfusions containing plasma exosomes from adults. 相似文献
18.
Carmen de Jesús-Gil Lídia Sans-de San Nicols Ester Ruiz-Romeu Marta Ferran Laura Soria-Martínez Irene García-Jimnez Anca Chiriac Josep Manel Casanova-Seuma Josep Manel Fernndez-Armenteros Sherry Owens Antonio Celada Michael D. Howell Ramn María Pujol Luis Francisco Santamaria-Babí 《International journal of molecular sciences》2021,22(4)
Candida albicans (CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA− cutaneous lymphocyte antigen (CLA)+/− T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, n = 52), and also healthy individuals (n = 17). A complete proteomic profile was also evaluated in plaque psoriasis patients (cohort 2, n = 114) regarding their anti-CA IgA levels. Increased anti-CA IgA and IgG levels are present in the plasma from plaque but not guttate psoriasis compared to healthy controls. CA cellular response is confined to CLA+ T cells and is primarily Th17. The levels of anti-CA IgA are directly associated with CLA+ Th17 response in plaque psoriasis. Proteomic analysis revealed distinct profiles in psoriasis patients with high anti-CA IgA. C-C motif chemokine ligand 18, chitinase-3-like protein 1 and azurocidin were significantly elevated in the plasma from plaque psoriasis patients with high anti-CA levels and severe disease. Our results indicate a mechanism by which Candida albicans exposure can trigger a clinically relevant IL-17 response in psoriasis. Assessing anti-CA IgA levels may be useful in order to evaluate chronic psoriasis patients. 相似文献
19.
Mireia Casanovas Irene Reyes-Resina Alejandro Lillo Jaume Lillo Raul Lpez-Arnau Jorge Camarasa Elena Escubedo Gemma Navarro Rafael Franco 《International journal of molecular sciences》2021,22(5)
Methamphetamine is, worldwide, one of the most consumed drugs of abuse. One important side effect is neurodegeneration leading to a decrease in life expectancy. The aim of this paper was to check whether the drug affects one of the receptors involved in neurodegeneration/neuroprotection events, namely the adenosine A2A receptor (A2AR). First, we noticed that methamphetamine does not affect A2A functionality if the receptor is expressed in a heterologous system. However, A2AR becomes sensitive to the drug upon complexes formation with the cannabinoid CB1 receptor (CB1R) and the sigma 1 receptor (σ1R). Signaling via both adenosine A2AR and cannabinoid CB1R was affected by methamphetamine in cells co-expressing the two receptors. In striatal primary cultures, the A2AR–CB1R heteromer complex was detected and methamphetamine not only altered its expression but completely blocked the A2AR- and the CB1R-mediated activation of the mitogen activated protein kinase (MAPK) pathway. In conclusion, methamphetamine, with the participation of σ1R, alters the expression and function of two interacting receptors, A2AR, which is a therapeutic target for neuroprotection, and CB1R, which is the most abundant G protein-coupled receptor (GPCR) in the brain. 相似文献
20.