乌江水电开发环境保护工作的探索与实践

乌江是目前我国按规划实施开发较为充分的典型河流之一.乌江水电开发环境保护工作见证了我国经济建设由注重经济效益向协调环境效益和社会效益实现可持续发展的转变,见证了我国水电开发环境保护工作逐步认识、探索实践与发展完善的过程.本文回顾了乌江水电开发环境保护工作的历程,介绍了乌江水电开发环境保护典型措施及工作经验,提出了当前水...     

新余钢铁厂三期板坯连铸机系统分析

本系统分析建立在理论设计和实际应用的基础上总结的,其系统构成有很强的针对性,设计思想在其他行业中也可用到。本文比较详细的叙述了连铸系统的工艺流程;并且由于系统本身的扩展性较强,系统的适应性也比较强。     

图书电子商务网站的设计与实现

阐述基于ASP.NET技术构建一个实现网上购物的图书电子商务网站,并详细分析了系统的功能需求,及主要功能模块的设计与实现方法。该系统将Web技术和数据库技术很好地融合在一起,使数据库成为Web的重要组成部分,实现了数据库技术和网络技术的有机结合。     

Simultaneous stabilization for a collection of nonlinear control systems in canonical form

A controller design method is provided to simultaneously stabilize a collection of nonlinear control systems in canonical form. It is shown that, under a mild assumption, any collection of nonlinear systems in canonical form can be simultaneously stabilized by one continuous state feedback controller. A constructive universal formula is presented explicitly. An illustrative example is given to demonstrate the validity of the method. Copyright © 2009 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society     

Magnitude bounds of generalized frequency response functions for nonlinear Volterra systems described by NARX model

In order to reveal the relationship between system time domain model parameters and system frequency response functions, new magnitude bounds of frequency response functions for nonlinear Volterra systems described by NARX model are established. The magnitude bound of the nth-order generalized frequency response function (GFRF) can be expressed as a simple n-degree polynomial function of the magnitude of the first order GFRF, whose coefficients are functions of the model parameters and frequency variables. Thus the system output spectrum can also be bounded by a polynomial function of the magnitude of the first order GFRF. These results demonstrate explicitly the analytical relationship between model parameters and system frequency response functions, and provide a significant insight into the magnitude based analysis and synthesis of nonlinear systems in the frequency domain.     

Promote Intratumoral Drug Release and Penetration to Counteract Docetaxel-Induced Metastasis by Photosensitizer-Modified Red Blood Cell Membrane-Coated Nanoparticle

The red blood cell membrane (RBCm) provides tight protection, lowers the immunogenicity, and prolongs the circulation time of drugs in vivo when acting as the coating of drug delivery systems. However, the cellular uptake and release of drugs are hindered by RBCm. Docetaxel (DTX) is the first-line medicine for treating triple-negative breast cancer (TNBC), but it induces tumor metastasis. To solve these dilemmas, in this study, the photosensitizer 1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide (DiR)-modified RBCm (DM) is prepared, which is coated onto a hybrid micelle consisting of the prodrugs of DTX and the anti-metastasis agent calcitriol (CTL), obtaining a nanoparticle, named HDC-DM. In a 4T1 tumor-bearing mouse model, after injecting HDC-DM, the intratumoral DTX and CTL concentrations are increased by 1.7 and 2.5 times compared with the free drug groups. After irradiating tumors with near-infrared laser, DiR elicits the photothermal effect, triggering the rupture of RBCm and drug release, promoting drug penetration in tumors, and inducing immunogenic cell death. The tumor growth inhibition rate is 77%, and the formation of lung metastases is reduced by 82%, with good biocompatibility. It is suggested that the combination of phototherapy, chemotherapy, and anti-metastatic therapy using HDC-DM is expected to be a powerful strategy for treating TNBC.     

Flexible Transparent Bifunctional Capacitive Sensors with Superior Areal Capacitance and Sensing Capability based on PEDOT:PSS/MXene/Ag Grid Hybrid Electrodes

Flexible transparent supercapacitors (FTSs) have aroused considerable attention. Nonetheless, balancing energy storage capability and transparency remains challenging. Herein, a new type of FTSs with both excellent energy storage and superior transparency is developed based on PEDOT:PSS/MXene/Ag grid ternary hybrid electrodes. The hybrid electrodes can synergistically utilize the high optoelectronic properties of Ag grids, the excellent capacitive performance of MXenes, and the superior chemical stability of PEDOT:PSS, thus, simultaneously demonstrating excellent optoelectronic properties (T: ≈89%, R_s: ≈39 Ω sq⁻¹), high areal specific capacitance, superior mechanical softness, and excellent anti-oxidation capability. Due to the excellent comprehensive performances of the hybrid electrodes, the resulting FTSs exhibit both high optical transparency (≈71% and ≈60%) and large areal specific capacitance (≈3.7 and ≈12 mF cm⁻²) besides superior energy storage capacity (P: 200.93, E: 0.24 µWh cm⁻²). Notably, the FTSs show not only excellent energy storage but also exceptional sensing capability, viable for human activity recognition. This is the first time to achieve FTSs that combine high transparency, excellent energy storage and good sensing all-in-one, which make them stand out from conventional flexible supercapacitors and promising for next-generation smart flexible energy storage devices.     

Pseudo-T2 mapping for normalization of T2-weighted prostate MRI

Magnetic Resonance Materials in Physics, Biology and Medicine - Signal intensity normalization is necessary to reduce heterogeneity in T2-weighted (T2W) magnetic resonance imaging (MRI) for...     

POI recommendation based on a multiple bipartite graph network model

The Journal of Supercomputing - In location-based social network platforms, the point-of-interest(POI) recommendation is an essential function to serve users. The existing POI recommendation...     

Identification of local cyclic stress‐strain curves at material inhomogeneities on the basis of digital image correlation

Low‐cycle fatigue (LCF) tests on butt‐welded joints revealed that material inhomogeneities become decisive for the fatigue behavior at elastic‐plastic strain amplitudes and the geometrical notch is no longer the failure location – as observed in high‐cycle fatigue (HCF) regime. Digital image correlation techniques enable the measurement of local strains at the surface of the welded region. A new method is proposed that is able to calculate related local stresses and identifies local cyclic material properties in structures of inhomogeneous material and geometry. This method combines strain measurements and Finite Element simulations. It is a fast iteration procedure that is able to perform the identification within less than ten iterative steps at several hundred local points. Transient material behavior is easy to capture and an application at high temperatures is anticipated due to the method is based on materials mechanics.