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151.
PURPOSE: We studied serum ELAM-1 levels in colon cancer patients. METHODS AND RESULTS: Serum ELAM-1 levels were significantly higher in 52 patients with colon cancer (mean +/- standard deviation, 69.3 +/- 28.6 U/ml) compared with 32 healthy volunteers (36.5 +/- 11.9 U/ml; P < 0.001). The mean serum ELAM-1 level in patients with metastatic tumors was significantly greater than that of patients with nonmetastatic tumors. Sensitivity and specificity of serum ELAM-1 elevation in detecting metastasis was 75 and 87.5 percent, respectively. Those of carcinoembryonic antigen and carbohydrate antigen 19-9 elevations were 71.4 and 62.5 percent and 35.7 and 91.7 percent, respectively. Twenty-five (89.3 percent) of 28 metastatic tumors showed either serum ELAM-1 or carcinoembryonic antigen elevation. There were weak but significant correlations found between serum ELAM-1 and carcinoembryonic antigen or carbohydrate antigen 19-9 levels. Moreover, serum ELAM-1 increased before detecting the recurrence by imaging in five of seven recurrent colon cancer patients. CONCLUSION: These findings suggest that serum ELAM-1 could be a useful tumor marker for colon cancer, especially in synchronous and metaclonous metastasis.  相似文献   
152.
Although appraisal theories have received strong empirical support, there are methodological concerns about the research, including biased recall, heuristic responding, ethical issues, and weak and unrealistic induction of emotions in laboratories. To provide a more ecologically valid test of appraisal theories, the authors used ecological momentary assessment, in which the emotions and appraisals of Singaporean police officers were measured online over the course of an ordinary workday. The research focused on happiness. Support was obtained for predictions, demonstrating the generalizability of appraisal theories to a nonlaboratory setting and circumventing the shortcomings of previously used methodologies. Also, evidence was obtained that happiness was reported primarily in association with a specific combination of 3 relevant appraisals: high pleasantness, high perceived control, and low moral violation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
153.
154.
The Gator Tech Smart House: a programmable pervasive space   总被引:9,自引:0,他引:9  
Research groups in both academia and industry have developed prototype systems to demonstrate the benefits of pervasive computing in various application domains. Unfortunately, many first-generation pervasive computing systems lack the ability to evolve as new technologies emerge or as an application domain matures. To address this limitation, the University of Florida's Mobile and Pervasive Computing Laboratory is developing programmable pervasive spaces in which a smart space exists as both a runtime environment and a software library. Service discovery and gateway protocols automatically integrate system components using generic middleware that maintains a service definition for each sensor and actuator in the space. The Gator Tech Smart House in Gainesville, Florida, is the culmination of more than five years of research in pervasive and mobile computing. The project's goal is to create assistive environments such as homes that can sense themselves and their residents and enact mappings between the physical world and remote monitoring and intervention services.  相似文献   
155.
Glass of nominal composition Sr0.6La0.4Fe11.6Co0.4O19 + 12SrB2O4 was prepared by rapidly quenching an oxide melt and was then heat-treated at temperatures from 550 to 900°C to give glass-ceramics containing fine lanthanum-and cobalt-doped strontium hexaferrite particles and microcrystalline SrB2O4. The materials were characterized by x-ray diffraction, scanning electron microscopy, electron probe x-ray microanalysis, and magnetic measurements. The coercivity of the glass-ceramic samples was shown to increase up to 427 kA/m with increasing heat-treatment temperature. The saturation magnetization of the samples increases up to 25.0 A m2/kg as the heat-treatment temperature is raised to 750°C, and decreases slightly at higher temperatures. Dissolving the nonmagnetic matrix of the glass-ceramic prepared at 900°C, we obtained submicron powder of composition Sr0.88La0.12Fe10.74Co0.47Oy, as determined by x-ray microanalysis.  相似文献   
156.
Packaging multiple active and passive elements in a hybrid optical platform   总被引:1,自引:0,他引:1  
The commercial market for telecom components has had an increasing demand for laser transmitter packages with higher functionality and smaller form factor. These higher levels of integration require an optical bench platform that can incorporate multiple active and passive elements and withstand stringent reliability requirements. Furthermore, the laser package must be compatible with high-volume manufacturing. We have developed an optical platform for building hybrid (multiple active elements) optoelectronic devices in a stable, hermetically sealed package. Two novel approaches to optical packaging have been developed: a localized laser soldering process and a flexure-based lens mount with large dynamic range. We present the optical bench and component design and the results of engineering reliability testing of the assembled package.  相似文献   
157.
Indirect measures have been used for the assessment of food preferences. These measures are indirect in the sense that the researcher does not ask a participant directly for his food preference, but derives his preference from a behavior. Typically, the affective priming paradigm and the Implicit Association Test have been used. The relevant processes in these paradigms are relatively automatic. One of the advantages of these paradigms is that responses are less likely to be influenced by socially desirable response tendencies and do not rely on the participant’s introspection. This paper provides an overview of research about relatively automatic associations with food in general and specifically for anorexia nervosa patients, dieters, and obese people. Multiple studies suggest that these paradigms can uncover food likes and dislikes. In most studies, no differences in food preferences were found between obese and lean people, or between restrained and unrestrained eaters. Possibly there simply are no group differences in automatic food associations. Alternatively, the employed indirect measures are not sensitive enough to detect truly existent differences. Interestingly, it was found that anorexia nervosa patients displayed a reduced sensitivity to the palatability of foods. Another interesting finding is that the presence of an immediate food related context influenced the automatic food associations. For now, the use of indirect measures in explaining differences between obese and lean people, and restrained and unrestrained eaters, does not seem a very viable approach. It might be for a clinical disorder such as anorexia nervosa.  相似文献   
158.
Lens major intrinsic protein (MIP) is the founding member of the MIP family of membrane channel proteins. Its isolation from ovine lens fibre cell membranes and its two-dimensional crystallization are described. Membranes were solubilized with N-octyl-beta-D-glucoside and proteins fractionated by sucrose gradient centrifugation containing decyl-beta-D-maltoside. MIP was purified by cation exchange chromatography, and homogeneity was assessed by mass analysis in the scanning transmission electron microscope. Purified MIP reconstituted into a lipid bilayer at a low lipid-to-protein ratio formed highly ordered tetragonal two-dimensional crystals. The square unit cell had a side length of 6.4 nm, and exhibited in negative stain four stain-excluding elongated domains surrounding a central stain-filled depression. Projection maps of freeze-dried crystals exhibited a resolution of 9 A, and revealed a monomer structure of MIP consisting of distinct densities. Despite significant differences in the packing of tetramers in the crystals, the projection map of the MIP monomer was similar to that of aquaporin-1 (AQP1), the first member of the MIP family which had its structure resolved to 6 A. Our protocols for the purification and reconstitution of MIP establish the feasibility for future work to visualize structure elements which determine the diverse functional properties of the MIP family members.  相似文献   
159.
为了了解ENIG化学变化对浸金耐蚀性的形响,探讨了浸金电镀溶液的pH值和化学性质与结果所得到的浸金层的耐蚀性之间的关系。  相似文献   
160.
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