Covalent Isoresonance

Two molecular species are defined to be isoresonant if each have like numbers of the same (type of) bonds and there is an isomorphism between superpositions of pairs of Kekulé structures giving equivalent interaction patterns (as appear in Hamiltonian matrices). Thus a close physico-chemical correspondence follows, as predicted by a variety of semiempirical quantum-chemical models, and thence presumably for corresponding molecules. Notably simple structural criteria sufficient for isoresonance are found.     

Briquetting the carbon phase from the sludge ponds at the Anzhersk deposit

The briquetting of coal slurries from the Anzhersk deposit in the Kuznets Basin is investigated. Petroleum binder and sodium lignosulfonate are employed. The solid carbon phase from the sludge ponds (ash content up to 35%) has adequate briquetting properties when petroleum binder is added. The use of sulfite waste liquor at pressures of 80–100 MPa yields mechanically strong briquets that require additional water protection.     

Introduction of biochemical wastewater purification at OOO Mechel-Koks (stage I)

Systems for mechanical and biological wastewater purification have been introduced at OOOMechel-Koks. This represents the first stage of a two-stage project to introduce biochemical purification. Results obtained in the adjustment and debugging of the systems are presented.     

High Speed Particle Beam Generation: A Dynamic Focusing Mechanism for Selecting Ultrafine Particles

RSMS-II is a unique characterization technique for analyzing the chemical content of individual airborne ultrafine particles in real time. Although based on earlier versions, the newest implementation offers crucial enhancements including a smart data acquisition system and a completely redesigned particle inlet. The particle inlet is based on a dynamic focusing mechanism that selectively transmits a narrow particle size range in the form of a high speed particle beam. The mean particle size that is optimally transmitted is dynamically altered by changing the nozzle source pressure, thus particles over a wide size range may be selected. Inherent in the design of dynamic focusing mechanisms is the ability to size-select particles based on their aerodynamic characteristics, thus obviating the need for additional sizing components. The principle, design, and calibration of a variable pressure inlet is presented in the current work. Characteristics are estimated employing a theoretical approach based on the Stokes number definition and supported with numerical simulations using CFD tools. Results from a preliminary effort in calibrating the inlet using monodisperse aerosol are presented. Results indicate that the size resolving capability of the inlet may be enhanced at the expense of lowered transmission rates. Finally, the capability of RSMS-II as a characterization technique is demonstrated by analyzing ultrafine atmospheric particles from a moderately polluted episode.     

Easyhaler® Multiple Dose Powder Inhaler—Practical and Effective Alternative to the Pressurized MDI

Due to the depletion of ozone layer linked to CFf propellants used in metered-dose inhalers (MDIs), alternative drug delivery systems for inhalation therapy of bronchial asthma is required. Dry powder inhalers have become a remarkable alternative to the MDIs. The research of powder delivery systems has strongly been focused on developing portable, preloaded multiple-dose powder inhalers, from which patients can reliably inhale several drug doses. Recently, a novel multiple-dose powder inhaler (Easyhaler®) has been developed. Easyhaler® is a suitable drug delivery system for various drugs already available or still under development. Optimum patient compliance is achieved by a design similar to the dose delivery system of the conventional MDI. In addition, the construction of the device allows high dose reproducibility and good in vitro and in vivo deposition of inhaled drug particles. Consequently, equal therapeutic efficacy, safety and tolerability with an MDI is documented in clinical trials. Thus the pharmaceutical, biopharmaceutical, and clinical features as well as the similar mode of use would facilitate a smooth transition from the freon based MDIs to the Easyhaler® multiple-dose powder inhaler.