Integrating Flexible Ultralight 3D Ni Micromesh Current Collector with NiCo Bimetallic Hydroxide for Smart Hybrid Supercapacitors

Flexible and lightweight supercapacitors with superior mechanical flexibility and outstanding capacity are regarded as an ideal power source for wearable electronic devices. Meanwhile, incorporating additional novel characters such as transparency and electrochromism can further benefit the development of smart supercapacitors. Nevertheless, the application of the commonly used planar-structural current collectors is seriously restricted by their intrinsic properties such as poor rigidity, large thickness, and limited loading surface area. Flexible and ultralight current collectors with 3D architecture, high conductivity, and easy integration are believed to be the most appropriate alternatives to build high-performance supercapacitors. In this study, a novel and scalable manufacturing technique is developed to produce a flexible and ultralight 3D Ni micromesh (3D NM) current collector for supercapacitor. Flexible smart supercapacitor integrated by 3D NM and high active Ni–Co bimetallic hydroxide (3D NM@NiCo BH) delivers a considerable rate performance (60.6% capacity retention from 1 to 50 mA cm⁻²). Furthermore, the fabricated hybrid supercapacitor device integrated with electrochromic functionality can visually indicate the energy level by a color display. This flexible electrochromic supercapacitor based on ultralight 3D Ni micromesh provides a novel insight into multifunctional energy storage systems for smart wearable electronic devices.     

Synergy of Immunostimulatory Genetherapy with Immune Checkpoint Blockade Motivates Immune Response to Eliminate Cancer

Normalizing the tumor-induced immune deficiency in the immunosuppressive tumor microenvironment (TME) through increasing the efficient infiltration and activation of antitumoral immunity in TME is the core of promising immunotherapy. Herein, a Cyclo(Arg-Gly-Asp-d -Phe-Lys) (RGD) peptides-modified combinatorial immunotherapy system based on the self-assembly of the nanoparticles named RGD-DMA composed of RGD-PEG-PLA, methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) and 1,2-Dioleoyl-3-trimethylammonium-propane (DOTAP) is used to codeliver the immunostimulatory chemokine CCL19-encoding plasmid DNA (CCL19 pDNA) and immune checkpoint ligand PD-L1 inhibitor (BMS-1). The RGD-DMA/pCCL19-BMS-1 system not only exhibited significant inhibition of tumor progression but also induced locally high concentrations of immunostimulatory cytokines at tumor sites without causing an obviously systemic inflammatory response. The immunosuppressive TME is efficaciously reshaped by the coadministration of RGD-DMA/pCCL19 and BMS-1, as indicated by the activated T lymphocytes, increased intratumoral-infiltration of mature dendritic cells (DCs), and the repolarization of macrophages from pro-tumoral M2-phenotype toward tumoricidal M1-phenotype. The upregulated PD-L1 expression at tumor sites caused by the increased IFN-γ levels after immunostimulatory gene therapy further demonstrated the synergistic effects of BMS-1 in counteracting the inhibitory role of PD-L1 expression in antitumor immunity. Therefore, the combination of immunostimulating therapy and immune checkpoint inhibitor that synergistically target multiple immune regulatory pathways demonstrates significant potential as a novel immunotherapy approach.     

数字电路的演化设计方法

电路的演化设计方法是演化硬件研究的一个主要分支,它是开展演化硬件研究的基础,也是演化硬件得以具备自适应和自修复特性的技术前提。首先介绍了数字电路演化设计的理论基础,然后对系统开发所使用的硬件平台进行了描述,最后对电路演化设计的系统流程做了详细描述。为进一步深入到基于演化硬件的数字电路自适应和自修复技术研究打下了基础。     

Electrically Responsive Materials and Devices Directly Driven by the High Voltage of Triboelectric Nanogenerators

Smart materials with electrically responsive characteristics and devices relying on different electrostatic effects can be directly driven by triboelectric nanogenerators (TENGs). The open circuit voltage from a TENG can easily reach thousands of volts with a separation distance of a few millimeters and this high output voltage can be used to effectively drive or control some devices with high internal resistance. This kind of combination is the most straightforward way for achieving a self‐powered smart system. Hence, a detailed survey of electrically responsive materials and devices that can be successfully combined with TENG is summarized, including dielectric elastomers, piezoelectric materials, ferroelectric materials, electrostatic manipulators, electrostatic air cleaners, and field emission and mass spectrometers. Moreover, key factors in determining suitable materials or devices to work with TENG are clarified and an in‐depth discussion of the current challenges related to these combined systems is provided. With the cost‐effectiveness and simple manufacturing process, these TENG‐based composite systems have great application prospects in the field of smart mechanics, human–machine interaction systems, intelligent storage systems, self‐powered microfluidic chips, portable mass spectrometers, and so on.     

Pretilt Angle Effects on Liquid Crystal Response Time

Pretilt angle effect on liquid crystal dynamics is analyzed theoretically. Analytical expressions are derived to describe liquid crystal response time under nonzero pretilt angle conditions. The theoretical analysis is confirmed experimentally using vertically aligned liquid crystal cells. This finding quantitatively correlates pretilt angles with liquid crystal response time. This study improves the understanding of the liquid crystal dynamic process which is helpful for optimizing liquid crystal response time.     

矿用智能安全监控充电架矿灯管理系统分析

矿灯是煤矿工人必备的井下照明工具,矿灯的安全性能及使用管理与煤炭安全生产息息相关。目前安全性能高、体积小、重量轻的新型锂电池矿灯已逐渐普及,但是矿灯的信息化管理还很薄弱。为了适应煤矿现代化建设的需要、改善锂电池矿灯充电性能,实现矿灯的信息化管理,文中详细分析了集充电架管理、矿灯管理和考勤管理于一体的矿灯充电管理系统。     

VRP的数学模型及算法分析

随着我国物流业的飞速发展,车辆运输路线规划对于降低物流成本显得越来越重要。对车辆路线问题（VRP）进行了数学建模,总结了国内外的研究状况,并指出了今后的研究方向。     

大、中型地下车库智能寻车系统

为了提高停车场的服务水平,停车场智能管理系统是必不可少的.它已经在大部分停车场发挥着重要作用,在为人们停车带来方便的同时也具有良好的社会效益和经济效益.在大、中型地下车库中,车主返回停车场时,由于停车场太大或者地形不熟,车主容易找不到车,故提出了智能反向寻车系统.该系统可以帮助车主尽快找到车辆停放的区域,提高车主的满意...     

一种高性能Class D音频放大器PWM控制的设计

文中设计了一种应用于Class D音频放大器中高性能PWM控制。该控制能够在较宽的电源电压范围内,使调制锯齿波的输入电平及音频输入信号经过前置放大后的共模电平跟随电源电压的变化而变化。共模电平经过PWM比较器得到占空比随输入信号变化的控制信号,从而提高系统的输出功率。仿真结果显示,当电源电压在2．4-5V范围变化时．音频信号和调制锯齿波的共模电平偏差在2mV以内,同时锯齿波的幅度也随着电源电压的升高而升高．显示了良好的线性跟随性。     

ANSYS在脉冲CO_2激光对K9玻璃损伤过程模拟中的应用研究

从脉冲CO2激光损伤K9玻璃有限元模型的建立和网格划分、脉冲激光的加载、设置初始条件和边界条件等几个方面,分析了基于ANSYS的脉冲CO2激光损伤K9玻璃模拟过程中的一些关键问题,建立了脉冲CO2激光损伤K9玻璃的有限元模型,对K9玻璃受到脉冲CO2激光辐照时的温度和应力分布进行了数值分析.