A short-term longitudinal study of impulsivity and antisocial behavior.

Analyzes the relationships between impulsivity and antisocial behavior in a noninstitutionalized sample, taking into account the multidimensional nature of impulsivity and the diversity of types of antisocial behavior. Data were obtained in 1989 and 1990 from 1,226 adolescents aged 12–18 yrs as part of a longitudinal study of risk factors for drug abuse and delinquency. The patterns of stability or change of the various dimensions of antisocial behavior (rule breaking, vandalism, theft, aggression, and drug taking) in relation to impulsivity were investigated. The results support that self-report measures of impulsivity are closely correlated with antisocial behavior among adolescents. The longitudinally-oriented analysis of this work also shows that impulsivity is associated with a future increase in antisocial behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

全20CrMnTi表面激光重熔的组织与性能研究

本文对激光重熔20CrMnTi材料表明改性层显微组织分布特征、表面硬度分布规律以及残余应力状态作了研究,结果表明,表面改性层由熔融层、相变硬化层及过渡层组成,且材料表面显微硬度得到大幅度提高,表面硬度达到HV841,约提高4倍。硬化层深度约1mm。残余应力测试得出最大残余应力出现在熔凝带中心,表现为压应力。随着离中心距离的增大,残余应力逐步降低,到熔化带边缘,表现为低幅值压应力;而熔池的外边缘应力在热影响区则转变为拉应力状态。     

An improved prediction of series resistance in spiral inductormodeling with eddy-current effect

Based on an earlier study by Kuhn and Ibrahim (see IEEE J. Trans. Microwave Theory Tech., vol. 49, no. 1, p. 31-38, 2001) on current crowding, an improved expression incorporating the skin effect for the prediction of series resistance in spiral inductor modeling has been derived. A modified model for the spiral inductor, which accounts for the eddy-current effect, is thus proposed. Relatively good agreements between the measured data and the results generated from the model are obtained     

Reperfusion injury delays healing of intestinal anastomosis in a rat

This SAEM position paper clarifies the role of emergency medicine in health care delivery. It builds upon the working definition of emergency medicine developed by the American College of Emergency Physicians in 1994 by describing the health care role of emergency physicians (EPs). EPs are first-contact providers who care for all patients regardless of age, gender, time of presentation, or ability to pay. They remain the only continuously accessible specialty for patients seeking help and solace in the health care system. They are an essential link in the health care continuum between primary care physicians, specialists, the out-of-hospital system, the patient, inpatient services, and communication services. The EP's role is in organizing and monitoring the emergency care delivery system. Part of this role is to better align the health care provider training and ability with the specific medical needs of a patient. The emergency health care system remains the essential medical safety net for all individuals needing care in this country.     

Prostate-specific antigen and its complexes with alpha 1-antichymotrypsin in the plasma of patients with prostatic disease

OBJECTIVE: To improve the specificity and sensitivity of the prostate-specific-antigen (PSA) assay for the distinction between prostate cancer and benign prostate hyperplasia (BPH). METHODS: Two sensitive immunoassays, one that measures free PSA and PSA complexed to alpha 1-antichymotrypsin (alpha 1-ACT) with the same efficiency (PSAag assay) and another that specifically measures the complex between PSA and alpha 1-ACT, have been designed to measure the PSA forms in the plasma of 84 patients with prostate disease and in the seminal plasma from 60 healthy individuals. RESULTS: The proportion of plasma PSA in complex with alpha 1-ACT was significantly higher in the 34 patients with prostate cancer (89 +/- 12%, mean +/- SD; median, 91%) than in the 50 patients with BPH (71 +/- 12%; 73%) and did not correlate with the total amount of PSA. Normal seminal plasma (n = 60) had 2.1 +/- 0.6 mg/ml PSA, 175 +/- 62 microns/ml alpha 1-ACT and 9.6 +/- 3.4 micrograms/ml PSA: alpha 1-ACT complex. CONCLUSION: These results confirm that PSA: alpha 1-ACT may be a good marker for a differential diagnosis of carcinoma of the prostate and BPH.     

Kinetics of modification of the mitochondrial succinate-ubiquinone reductase by 5,5''-dithiobis-(2-nitro-benzoic acid)

In the present study, we examined the effect of the thromboxane/prostaglandin endoperoxide analogue U46619 on proliferation and hypertrophy in cultured rat vascular smooth muscle cells and the roles of protein kinase C and transforming growth factor-beta (TGF-beta) in the mediation of the hypertrophic response to U46619. Since an increase in basic fibroblast growth factor (bFGF) was previously shown to mediate the hypertrophic response to U46619, we also assessed the relationship between bFGF and TGF-beta in the expression of U46619 actions. U46619 increased [35S]methionine incorporation into protein and protein content of vascular smooth muscle cells but had no effect on cell number. A role for TGF-beta was supported by the following observations: (1) exogenous human TGF-beta 1 increased protein synthesis; (2) antibody to TGF-beta blocked both TGF-beta- and U46619-induced increases in protein content; (3) U46619 increased active and total TGF-beta bioactivities; and (4) the actions of U46619 on protein content and TGF-beta bioactivity were blocked by the thromboxane/prostaglandin endoperoxide receptor antagonist SQ 29,548. Previous observations had demonstrated a role for bFGF in the expression of U46619 actions on protein synthesis. Results of the present study suggest that TGF-beta and bFGF interact in mediating the protein synthetic response to U46619. First, the concentration of exogenous TGF-beta (10 pmol/L) alone required to produce a protein synthetic response equivalent to that induced by U46619 was much higher than the concentration of endogenous active TGF-beta that accumulated in the media in response to U46619 (0.7 pmol/L). Second, bFGF (20 ng/mL) increased total TGF-beta bioactivity and stimulated protein synthesis. The hyper-trophic response to bFGF was blocked by anti-TGF-beta. The ability of U46619 and bFGF to increase protein synthesis and protein content in vascular smooth muscle cells was associated with TGF-beta-induced suppression of proliferation, as evidenced by the ability of antibody to TGF-beta to enhance U46619- and bFGF-induced increases in [3H]thymidine incorporation into DNA. Results of the present study also supported a role for protein kinase C in the expression of U46619 and bFGF actions. U46619 increased protein kinase C activity in the particulate fraction of vascular smooth muscle cells. Moreover, the protein kinase C inhibitors GF109203X and staurosporine blocked U46619- and bFGF-induced increases in protein synthesis as well as active and total TGF-beta bioactivities. By contrast, the protein kinase C inhibitors did not prevent the increases in protein synthesis induced by exogenous TGF-beta. The results demonstrate that thromboxane/prostaglandin endoperoxide signals increased TGF-beta bioactivity via protein kinase C. Increases in both bFGF and TGF-beta are required for an optimal hypertrophic response to U46619. The hypertrophic response to TGF-beta occurs through a protein kinase C-independent pathway.     

Fast convergent dyadic Green's function in a rectangular waveguide

Alternative formulas for the dyadic Green's function in a rectangular waveguide are presented. These new functions are deduced by modifying part of Rahmat-Samii's derivation procedures by employing the Poisson summation technique. The Green's function obtained owns fast convergence property and is proved to be more suitable for numerical applications.