基于B/S架构的组件式PACS系统设计

传统的PACS系统(医学影像存档与传输系统)几乎全都是采用C/S架构,该设计模式对软件发布后系统的部署、升级、维护都造成了极大的困难,而对于PACS这一类客户需求灵活多变的特殊软件系统,矛盾显得更为突出.针对该问题提出了一套完整的基于B/S架构的PACS系统解决方案,然后简要地分析了系统的各个功能模块,在此基础之上结合国内PACS的发展现状,又介绍了一种组件式PACS系统的设计方法,将这两者结合运用将给PACS系统的开发带来极大的方便.     

T400工艺板在飞剪电控系统改造中的应用

本文在起停式飞剪的电控系统改造中,采用基于T400工艺模块的分级分布式计算机控制系统,建立了控制系统的数学模型,并针对该控制系统进行了MATLAB仿真。仿真结果表明,该控制系统设计合理,调节系统的动、静态特性较好。     

一种轻量级RFID安全协议

在分析了几种现有的典型RFID安全协议的特点和缺陷的基础上,提出了一种轻量级的RFID安全协议,该协议将一次性密码本与询问一应答机制相结合,实现了安全高效的读取访问控制,最后建立该协议的理想化模型,利用BAN逻辑对该协议进行了形式化分析,在理论上证明其安全性.     

Pharmacophore and docking-based combined in-silico study of KDR inhibitors

The growth and metastasis of solid tumors is dependent on angiogenesis. The vascular endothelial growth factor (VEGF) and its cell surface receptor in human KDR (kinase domain containing receptor or VEGFR-2) have particular interest because of their importance in angiogenesis. The development of novel inhibitors of VEGFR-2 would be helpful to check the growth of tumors. Quantitative structure activity relationship (QSAR) analyses used to understand the structural factors affecting inhibitory potency of thiazole-substituted pyrazolone derivatives. Several pharmacophore-based models indicated the importance of steric, hydrophobic and hydrogen bond acceptor groups to inhibitory activity. The comparative molecular field analyses (CoMFA) and comparative molecular similarity indices analyses (CoMSIA) based 3D-QSAR models were derived using pharmacophore-based alignment. Both CoMFA (q² = 0.70, r² = 0.97 and ) and CoMSIA (q² = 0.54, r² = 0.82 and ) gave reasonable results. The molecular docking (receptor-guided technique) with a recently reported receptor structure (PDB = 1YWN) were performed. The docked alignment was subsequently used for 3D-QSAR (CoMFA; q² = 0.56, r² = 0.97, , CoMSIA; q² = 0.58 r² = 0.91, ). The overall both studies were indicated, steric, electrostatic and hydrogen bond acceptor effects contribute to the inhibitory activity. CoMFA and CoMSIA models suggested that a positive bulk with hydrophobic effect is desirable around position 4 and 5 and hydrogen bond acceptor groups around pyrazolones ring will be helpful.     

DEVS-Based modeling of VoIP spam callers’ behavior for SPIT level calculation

At the present time the VoIP (Voice over Internet Protocol) service is generally accepted as an alternative for people seeking cheaper means to make a phone call. Users of VoIP service may fall anywhere along a spectrum between types at two extremes: one of which is an ordinary caller who doesn’t use the telephone for commercial purposes, while the other is a person who generates spam calls for commercial purposes. The focus of this paper concerns modeling of spam callers’ behavior to calculate the SPIT (Spam over Internet Telephony) level for management of the quality of service. From the perspective of a VoIP service provider’s view, spam callers are also a type of customer and sometimes they are valuable for increasing revenue. However, if a service provider does not manage spam calls, it can harm their business, because ordinary users might not receive phone calls using the phone numbers of the VoIP service. Thus, there is a trade-off between revenues and usability in managing spam calls in the VoIP service. This work presents a model of spam caller’s behavior using the DEVS (Discrete Event System Specification) formalism. The DEVS formalism is applicable as a model of behavior, by defining the state and state transition of the target of the model. In our model, we use six main parameters to define the states and state transitions. Each state is represented by a number which indicates the SPIT level of a caller. If the value is 1.0 then the caller is more similar to a spam caller. Based on the model definition, we constructed a SPIT level Calculation UI (User Interface) that is used to manage spam calls to improve VoIP service quality.     

高速可配置Rijndael算法的设计与实现

针对网络通信的安全要求,给出了在集成电路设计中实现Rijndael算法的高吞吐率解决方案。对算法实现进行了优化,具有支持密钥长度和数据长度的可变选择与组合配置,加密和解密工作通道完全独立,全双工安全高速通信等特点。已通过了FPGA的验证与电路实现。通过对比分析综合仿真结果,该实现相对于目前已知的实现方案在性能和速度上具有很大的优势。     

基于Web的学科教学服务平台的应用研究

以网络教育为手段,以学校培养人才的目标、学科建设的方向和学生实际情况为依据,探索和研究网络教学服务平台的结构模型和实现方法。分析了当前网络教学平台存在的不足,在此基础上以学校的应用定位、学科发展的方向和学生实际情况为依据,提出了一个基于Web的学科教学服务平台系统结构。根据该结构设计了一个基于n层结构的．NET实现模型。利用该模型实现了一个基于．NET的《计算机辅助教学》教学服务平台。该平台的建立有效地弥补了我校《计算机辅助教学》网络教学的不足。     

Proteomic analysis of sera of asymptomatic,early‐stage patients with Wilson's disease

Wilson's disease (WD) is characterized by excessive accumulation of intracellular copper in liver and extrahepatic tissues, leading to significant oxidative stress and tissue damage. To date, several diagnostic biomarkers for WD such as serum ceruloplasmin, serum or urine copper levels and copper content in liver have been identified. However, these biomarkers may not be convincing for the diagnosis in some WD patients. To identify additional novel diagnostic biomarkers, we compared the serum protein profiles of asymptomatic childhood WD patients (n=20), without neurologic manifestation or liver cirrhosis, with normal controls (n=13). Fourteen spots, five up‐regulated and nine down‐regulated (>2‐fold), were differentially expressed in WD patients in comparison to normal control on 2‐DE. Among them, three spots were down‐regulated in both male and female WD. MS/MS analysis revealed that the three spots were complement component C3, complement factor B and alpha‐2 macroglobulin. By comparative proteome analysis, complement component C3, complement factor B and alpha‐2 macroglobulin, which are related to oxidative stress and inflammation, turned out to be good candidates for novel diagnostic biomarkers for early stages of WD.     

Complex Attributed Network Embedding for medical complication prediction

Knowledge and Information Systems - To assure the development of effective treatment plans, it is crucial for understanding the complication relationships among diseases. In practice, traditional...     

Friendly spectrum jamming against MIMO eavesdropping

Wireless Networks - Friendly spectrum jamming is a flexible scheme to establish secure communications among heterogeneous wireless devices without the need of encryption. Previous works have...