Twenty-seven painful knee replacements were evaluated arthroscopically. The diagnostic and therapeutic value of these arthroscopic procedures was studied retrospectively. In 5 of the 27 cases, the arthroscopy revealed no diagnosis for the pain. Some form of arthroscopic treatment was performed in 20 cases; in 6 of these 20 cases, however, the treatment did not reduce the pain. Based on these findings, we conclude that the indications for arthroscopic evaluation and treatment of painful knee prostheses are limited. 相似文献
Volatile anaesthetics have historically been considered to act in a nonspecific manner on the central nervous system. More recent studies, however, have revealed that the receptors for inhibitory neurotransmitters such as gamma-aminobutyric acid (GABA) and glycine are sensitive to clinically relevant concentrations of inhaled anaesthetics. The function of GABA(A) and glycine receptors is enhanced by a number of anaesthetics and alcohols, whereas activity of the related GABA rho1 receptor is reduced. We have used this difference in pharmacology to investigate the molecular basis for modulation of these receptors by anaesthetics and alcohols. By using chimaeric receptor constructs, we have identified a region of 45 amino-acid residues that is both necessary and sufficient for the enhancement of receptor function. Within this region, two specific amino-acid residues in transmembrane domains 2 and 3 are critical for allosteric modulation of both GABA(A) and glycine receptors by alcohols and two volatile anaesthetics. These observations support the idea that anaesthetics exert a specific effect on these ion-channel proteins, and allow for the future testing of specific hypotheses of the action of anaesthetics. 相似文献
This paper is concerned with the flow behavior of isotropic solutions of the rod-like polymer, poly(p-phenyleneterephthalamide) (PPT), in 100 percent sulfuric acid. Studies include entry flow visualization in a slit die and solution fracture, and die swell in capillaries and a slit die. It was observed that solutions of PPT exhibit nearly negligible die swell, a slip-stick type of fracture that disappears at high shear rates, and radial entry flow patterns similar to Newtonian fluids. Fracture was associated with the plateau in the shear stress vs shear rate curve. Because values of the wall shear stress (τw.) obtained from capillary measurements were in good agreement with those obtained from a cone-and-plate rheometer and values of the loss modulus (G″) obtained from small-strain dynamic oscillatory measurements, it is believed that the rheological properties lead to the flow instability. These results are in agreement with the predictions of a recent theory by Doi and Edwards for concentrated solutions of rod-like molecules. Data are also presented for a flexible chain polyamide, nylon 6,6, in 100 percent H2SO4 for the purpose of comparing the flow characteristics of rigid and flexible chain polymers. 相似文献
The constituents of the neutral aromatic polar subfractions of two coal-derived oils, a shale-derived oil and a petroleum oil were analysed and compared. Chemical ionization mass spectra, using methanol and ammonia as reagent gases, were used to characterize the oxygen-and nitrogen-containing constituents, respectively. The compositions of the petroleum substitutes were found to differ from those of petroleum in containing primary polycyclic aromatic amines, azaarenes, polycyclic hydroxyaromatics and, in one case, aromatic ketones. 相似文献
Electrochemical oxidation of Mn2+ in sulphuric acid to form MnO2 was studied using stationary and rotating platinum/platinum ring-disc electrodes. It appears that nucleation of MnO2 is governed by an equilibrium involving a Mn(III) intermediate. Growth of MnO2 involves the reduction of MnO2 surfaces by Mn2+ ions in the solution to form MnOOH intermediates. The subsequent electrochemical oxidation of MnOOH releases a hydrogen ion and results in the formation of MnO2. The rate constant of MnOOH oxidation to MnO2 was estimated to be 40 s–1. With a sufficient supply of Mn2+ ions, a layer of MnOOH is built up and the in-solid diffusion of hydrogen ions becomes the ratedetermining-step. With a low Mn2+ concentration, diffusion of Mn2+ ions from bulk electrolyte to the MnO2/electrolyte interface is a factor controlling the growth of MnO2. The activation energy and the pre-exponential term of the diffusion coefficient of Mn2+ in 0.5m sulphuric acid were determined to be 44.8 kJ mol–1 and 100 cm2 s–1, respectively. 相似文献
A new type of mesoporous silica has been prepared which showed 780 m2/g of BET surface area and 0.6 ml/g of primary mesopores narrowly distributed around 4.2 nm. More importantly however, is that it showed short-range zeolite crystallinity as demonstrated by FTIR and XRD analysis, and hydrophobicity as demonstrated by water and n-hexane adsorption.
This material was synthesized via a dual-template, three-step hydrothermal–flocculation–steaming synthesis procedure developed by us recently. Briefly, MFI nanoprecursors (NPs) were first prepared by a low-temperature hydrothermal step using TPAOH as template for zeolite structure, and then flocculated using a surfactant that served as the template for the mesopores. The collected NPs are mesoporous silica exhibiting short-range MFI domains when directly calcined. However, the steaming step promoted the crystallization of the NPs and created uniform mesopores. It was found that almost every detail in these procedures affected the properties of the final product. The most important variables, however, were identified as the duration the flocculants were kept in contact with the liquid phase, and the humidity under which the steaming was conducted. By properly adjusting the procedures, the said mesoporous silica, as well as nanocrystals having high external surface area, could be produced at will. 相似文献
The high-cleaning Lyocell fibers are used to spin the Ne 32 yarns for an open-end rotor spinning frame. The optimal processing parameters were obtained in demonstrating output speed, stretching roller speed, feed speed and rotor revolution. The quality characteristics, such as yarn count, strength, elongation and Um (%), are far beyond the rating standard of the combed yarn. No yarn breaking for continuous spinning during the experimental confirmation. The result presents lower yarn breaking rate and maintains stabilized output status of spinning conditions. The back propagation neural network was employed for learning, forecast and verification of the processing parameters. 相似文献