Protective Effect of Water-Soluble C60 Fullerene Nanoparticles on the Ischemia-Reperfusion Injury of the Muscle Soleus in Rats

The biomechanical parameters of muscle soleus contraction in rats and their blood biochemical indicators after the intramuscular administration of water-soluble C₆₀ fullerene at doses of 0.5, 1, and 2 mg/kg 1 h before the onset of muscle ischemia were investigated. In particular, changes in the contraction force of the ischemic muscle soleus, the integrated power of the muscle, the time to achieve the maximum force response, the dynamics of fatigue processes, and the parameters of the transition from dentate to smooth tetanus, levels of creatinine, creatine kinase, lactate and lactate dehydrogenase, and parameters of prooxidant–antioxidant balance (thiobarbituric acid reactive substances, hydrogen peroxide, and reduced glutathione and catalase) were analyzed. The positive therapeutic changes in the studied biomechanical and biochemical markers were revealed, which indicate the possibility of using water-soluble C₆₀ fullerenes as effective prophylactic nanoagents to reduce the severity of pathological conditions of the muscular system caused by ischemic damage to skeletal muscles.     

基于穴位点体温差别的药效监测系统设计

设计了一种通过检测生物活性点与皮肤完整区域之间温度差来监测药物疗效并优化心理疾病治疗的系统。该系统通过实时监控服药计量,以及时调整药量,从而提高治疗的有效性。系统采用两电极 Foll方法结合中该地形解剖参考点找到生物活性点,通过 DS18B20测量温度,利用 ATmega 32单片机对温度进行处理并实时显示温度差,进而通过温度差反应药效。本文数据证实了温差指标 BAP C7、Gi4与评估心理疾病严重程度的神经尺度之间的相关性。实验结果表明,温度差指标能够作为衡量药效的标准,通过监测温度差可以有效实现心理疾病药效的监测。     

Monitoring the Technical Condition of Dams of Hydroelectric Power Plants with an Automated Monitoring and Earthquake Registration System

An approach is described that has been developed for auxiliary monitoring of technical condition of hydropower plant dams. It is based on analysis of changes in dynamic characteristics of dams obtained by an automated monitoring and earthquake registration system that records microseismic vibrations of structures. The configuration of the system as well as the results of seismometric monitoring of the dam of Krasnoyarsk hydroelectric power plant are described. To study behavior of the dam under normal and extreme loads it was proposed to develop a model of the dam with the use of the finite element method.     

Characteristics of copper-clad aluminum rods prepared by horizontal continuous casting

An innovative horizontal continuous casting method was developed and successfully used to prepare copper-clad aluminum (CCA) rods with a diameter of 85 mm and a sheath thickness of 16 mm. The solidification structure and element distribution near the interface of the CCA ingots were investigated by means of a scanning electron microscope, an energy dispersive spectrometer, and an electron probe X-ray microanalyzer. The results showed that the proposed process can lead to a good metallurgical bond between Cu and Al. The interface between Cu and Al was a multilayered structure with a thickness of 200 μm, consisting of Cu₉Al₄, CuAl₂, α-Al/CuAl₂ eutectic, and α-Al + α-Al/CuAl₂ eutectic layers from the Cu side to the Al side. The mean tensile-shear strength of the CCA sample was 45 MPa, which fulfills the requirements for the further extrusion process. The bonding and diffusion mechanisms are also discussed in this paper.     

Econometric Modeling of the Influence of Relevant Indicators of Gender Policy on the Efficiency of a Banking System

The efficiency of a banking system in the context of gender policy is analyzed. The construction of a generalizing indicator of the efficiency of a banking system is carried out using relative normalization and Harrington’s desirability function. The impact of indicators of gender policy on the efficiency of a banking system is determined by means of correlation-regression and factor analysis tools.     

Synthesis,Structure, Properties,and Applications of Bimetallic Nanoparticles of Noble Metals

Bimetallic nanoparticles of noble metals are of high interest in imaging, biomedical devices, including nanomedicine, and heterogeneous catalysis. Synthesis, properties, characterization, biological properties, and practical applicability of nanoparticles on the basis of platinum group metals and the coin metals Ag and Au are discussed, also in comparison with the corresponding monometallic nanoparticles. In addition to the parameters that are required to characterize monometallic nanoparticles (mainly size, size distribution, shape, crystallographic nature, surface functionalization, charge), further information is required for a full characterization of bimetallic nanoparticles. This concerns the overall elemental composition of a bimetallic nanoparticle population (ratio of the two metals) and the internal distribution of the elements in individual nanoparticles (e.g., the presence of homogeneous alloys, core–shell systems, and possible intermediate stages). It is also important to ensure that all particles are identical in terms of elemental composition, that is, that the homogeneity of the particle population is given. Macroscopic properties like light absorption, antibacterial effects, and catalytic activity depend on these properties. The currently available methods for a full characterization of bimetallic nanoparticles are discussed, and future developments in this field are outlined.